Showing 601 - 620 results of 106,037 for search '(( 2 c decrease ) OR ( 5 ((((step decrease) OR (we decrease))) OR (mean decrease)) ))', query time: 1.76s Refine Results
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    Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress by Béatrice Chambraud (3371201)

    Published 2021
    “…</p> <p><b>Abbreviations:</b> AD: Alzheimer disease; AKT/protein kinase B: AKT serine/threonine kinase; ALP: Autophagy-lysosomal pathway; ATG: autophagy-related; BafA<sub>1</sub>: bafilomycin A<sub>1</sub>; CQ: chloroquine; CTSD: cathepsin D; DIV: days in vitro; DRG: dorsal root ganglion neurons; Dox: doxycycline; DNAJC5: DnaJ heat shock protein family (Hsp40) member C5; EL: empty lentiviral vectors; ENO2/NSE: enolase 2, gamma neuronal; FKBP4/FKBP52: FKBP prolyl isomerase 4; FTLD-Tau: frontotemporal lobar degeneration with Tau pathology; GFP: green fluorescent protein; LAMP1: lysosomal associated membrane protein 1; LDH: lactate dehydrogenase; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MAPT/Tau: microtubule associated protein tau; MTT: tetrazolium salt; NFTs: neurofibrillary tangles; RPE-1: retinal pigment epithelial cells; shRNA: small-hairpin ribonucleic acid; SQSTM1/p62: sequestosome 1; SD: standard deviation; SEM: standard error of the mean; SH-SY5Y: human neuroblastoma cells; Sh1 or Sh2: Lentiviral shRNA vectors inducing FKBP4 decrease; SH-52GFP: MAPT/Tau-inducible SH-SY5Y cell line constitutively expressing FKBP4-GFP; TUBB3/βIII tubulin: tubulin beta 3 class III; UPS: ubiquitin-proteasome system</p>…”
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    Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

    Published 2019
    “…Outcomes from the model included life expectancy, 10-year medical resource use, incremental cost-effectiveness ratios (ICERs) in $/year of life saved (YLS), and 5-year budget impact. We simulated people with HIV (PWH) in care (mean CD4: 259/<i>μ</i>L, SD 198/<i>μ</i>L) and transmitted cases. …”
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    Decreased expression levels of the MYO6 protein in <i>ksv</i> mice. by Yuta Seki (4385833)

    Published 2017
    “…Expression of MYO6 is completely ablated in the hair cells of <i>Myo6</i><sup>-/-</sup> mice (C). Scale bar = 5 μm. D and E. Western blot analysis of homogenates prepared from the inner ears of +/+, +/<i>ksv</i> and <i>ksv/ksv</i> mice at P30 detected with anti-MYO6 (N-ter, D) and MYO6 (C-ter, E) antibodies (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0183477#pone.0183477.s007" target="_blank">S2 Table</a>). …”
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    Thrombin-induced decreased lamellipodia protrusion frequency and actin stress fiber formation. by Jerome W. Breslin (548352)

    Published 2015
    “…<i>B</i>. Thrombin initially decreased the mean protrusion frequency of local lamellipodia. …”
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    Figure 5 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin by Joanna Domagala (21643925)

    Published 2025
    “…<b>I,</b> pH-dependent processing of perforin by human recombinant cathepsins B and L at concentrations ranging from 1 to 100 nmol/L, analyzed by Western blot methods using an anti-perforin antibody (B-D48 clone; <i>n</i> = 2). <b>J,</b> Processing of perforin by human recombinant granzyme B at concentrations of 0.5, 1, and 2.5 μmol/L, assessed at pH 7.4 in two different buffers (<i>n</i> = 2). …”
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