Enhancing of Women Functional Status with Metabolic Syndrome by Cardioprotective and Anti-Inflammatory Effects of Combined Aerobic and Resistance Training by Ramires Alsamir Tibana (656317)

“…There was an improvement in muscle strength on chest press (<i>p</i> = 0.009), isometric hand-grip strength (<i>p</i> = 0.03) and 30 s chair stand (<i>p</i> = 0.007). There was a decrease in SBP (p = 0.049), MBP (<i>p</i> = 0.041), Z-Score of MetS (<i>p</i> = 0.046), OPG (0.42±0.26 to 0.38±0.19 ng/mL, <i>p</i><0.05) and NOx (13.3±2.3 µmol/L to 9.1±2.3 µmol/L; <i>p</i><0.0005). …”

Table_1_Si-Miao-Yong-An Decoction Protects Against Cardiac Hypertrophy and Dysfunction by Inhibiting Platelet Aggregation and Activation.docx by Congping Su (7397702)

“…Conversely, SMYAD improved cardiac dysfunction with preserved left ventricular ejection fraction (66.5 ± 17.2%; P < 0.001). Shortening fraction was increased by SMYAD, while the left ventricular internal diameter and left ventricular volume were decreased in SMYAD group. …”

Altered retinal morphology and visual function in XBP1 KO mice. by Yimin Zhong (159151)

“…ERG recordings show significantly decreased amplitude of a and b waves in both photopic and scotopic ERG in 4-month-old, but not in 2-month-old XBP1 KO mice.…”

PolyQ expansion affects p53-dependent apoptotic function in cells and in zebrafish. by Hongmei Liu (129385)

“…The ratio of embryos with the representative phenotypes was indicated. Both <i>WT</i> and <i>80Q</i> mRNA injections resulted in obvious <i>otx2</i> signal decreases in <i>p53 WT</i> but not <i>p53 mutant</i> zebrafishes, with more profound <i>otx2</i> signal reduction in <i>80Q</i> mRNA injections. …”

Increased tumor incidence and modification of the tumor spectrum in <i>Rnf8^−/−p53^+/−</i> mice. by Marie-Jo Halaby (278342)

“…(F) The same lymphoma has also invaded liver tissue. Bars: B: 200 µm, C: 100 µm, D–G: 50 µm. (G) Southern blot showing loss of <i>WT</i> p53 allele in <i>Rnf8^−/−p53^+/−</i> tumors (tumor 1: rhabdomyosarcoma; tumors 2 & 3: thymomas, tumor 4 & 5 lymphomas, tumors 6 & 7 thymomas). …”

Feedback patterns of avian longitudinal-experimental immune responses against West Nile Virus. by Ariel L. Rivas (155906)

“…The 3D relationship that included the heterophil (N) %, the ratio of N per lymphocyte (N/L), and the mononuclear cell/N (macrophage plus lymphocyte/N or MC/N) ratio showed three major data inflections: 1) a double 90-degree inflection was observed between pre-inoculation (0 dpi) and one day post-inoculation (1 dpi) data points (green arrow), indicating that the N/L ratio increased within a 24-hour period, and that high N/L observations were D+ (red symbols); 2) at, approximately, 5 dpi, a second data inflection was observed (red arrow), which was associated with high MC/N and low N/L values; and 3) soon after 5 dpi, the third data inflection took place, indicating the beginning of the return to the steady state phase (blue arrow). …”

Retinoic acid signaling responsiveness in the periocular region. by Glenda Evangelina Comai (9652709)

“…<p><b>(A-C)</b> Macroscopic views of endogenous GFP fluorescence of <i>Tg:RARE-CreERT2;R</i>^{<i>26mTmG</i>} embryos. …”

Animation 1 by Vina Putra (20363598)

“…Previous studies showed that this compression results in both a decrease in cell volume as well as a change in the shape of the nucleus (shape shift due to compression)​11​. …”

Data Sheet 1_16S rRNA and metabolomics reveal the key microbes and key metabolites that regulate diarrhea in Holstein male calves.docx by P. P. Cao (20565548)

“…</p>Results<p>Our findings indicated a high prevalence of diarrhea among calves between 1–4 weeks of age on pasture, which led to a marked decrease in growth performance, including average daily gain. …”

The AgB-specific IL-1ra, IL-6, IL-8, FGF, G-CFS, IFN-γ, MIP-1α, IP-10 and MCP-1 levels in patients in the CE3b-group are significantly reduced overtime. by Linda Petrone (339785)

“…In patients in the CE3b-group a significant decrease of IL-1ra (<b>A</b>), IL-6 (<b>B</b>), IL-8 (<b>C</b>), FGF (<b>D</b>), G-CSF (<b>E</b>), IFN-γ (<b>F</b>), IP-10 (<b>G</b>), MCP-1 (<b>H</b>) and MIP-1α (<b>I</b>) at T1 compared to T0 was observed. …”

Trypanosoma cruzi induces changes in gene expression of glucocorticoid and prolactin receptors in CD4⁺CD8⁺ cells and alters their sensitivity to GC-induced ap... by Ailin Lepletier (328461)

“…One million cells/animal were incubated with DEX (10⁻⁹ M) or RPMI (vehicle) during 8 hours under 37°C at 5% CO₂ atmosphere. Thymocytes were then washed and incubated with anti-CD4/APC, anti-CD8/PercP or Annexin-V/FITC, for the cytofluorometric characterization of apoptosis within each thymocyte subset. …”

Supplementary Material for: Genome-Wide Analysis of Dietary Eicosapentaenoic Acid- and Oleic Acid-Induced Modulation of Colon Inflammation in Interleukin-10 Gene-Deficient Mice by Knoch B. (4118734)

“…<i>Results:</i> In this study, dietary EPA reversed the decrease in colon fatty acid β-oxidation gene expression observed in OA-fed <i>Il10</i>^–/– compared to C57 mice. …”

Table_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.docx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

DataSheet_1_Representing true plant genomes: haplotype-resolved hybrid pepper genome with trio-binning.xlsx by Emily E. Delorean (17399242)

“…However, most genome assembly methods that have been used in plants result in a merged single sequence representation that is not a true biologically accurate representation of either haplotype within a diploid individual. …”

WIDS 2020 Poster(Wafaa Alabsi).pdf by Wafaa Alabsi (8704977)

“…</p> <p><b>Results</b></p> <p>The glycosylation of numerous peptides synthesized in our group including PNA5 has been shown to increase enzymatic stability and penetration of the BBB; decrease the clearance rate; thus, increase the half-life (t_1/2), the area under the curve (AUC) and the maximum concentration C_max.…”

Video1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.MP4 by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Image4_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Video3_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.MP4 by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Image1_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”

Image3_Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment.TIF by Kai Wang (21246)

“…We found that chronic mavacamten treatment of R403Q ECTs: (i) shortened relaxation time, (ii) reduced APD₉₀ prolongation, (iii) upregulated ADRB2, ATP2A2, RYR2, and CACNA1C, (iv) decreased B-type natriuretic peptide (BNP) mRNA and protein expression levels, and (v) increased sarcomere length and reduced sarcomere disarray.…”