Profile and variability of intraocular pressure after the EX-PRESS device implant by Rodrigo Egidio da Silva (4986470)

“…Concomitantly, there was a considerable decrease in anti-glaucomatous medications, and few associated complications.…”

M002 treatment of malignant rhabdoid kidney tumor xenografts. by Michael L. Megison (469463)

“…In the M002 treated G401 xenografts, there was a significant decrease in tumor growth that began at day 7 following treatment that continued to the end of the study. …”

Cocrystals of Pentoxifylline: In Silico and Experimental Screening by Dmitrijs Stepanovs (1556632)

Cocrystals of Pentoxifylline: In Silico and Experimental Screening by Dmitrijs Stepanovs (1556632)

Cocrystals of Pentoxifylline: In Silico and Experimental Screening by Dmitrijs Stepanovs (1556632)

Over-expression of NF-Y or USF increases <i>Miwi</i>-luciferase activity. by Yu Hou (164094)

“…GC-1 or COS7 cells were transfected with 0.2 µg pGL3-5M4 and 0.2 µg NF-Y expression plasmids (pCX-NFYa, pCX-NFYb, pCX-NFYc) as indicated. b), The mutated CCAAT box construct pGL3-5M4-Cmut (0.2 µg) contransfected with NF-Y expression plasmids (pCX-NFYa, pCX-NFYb, pCX-NFYc) as indicated, does not increase the <i>Miwi</i>-luciferase activity. c), The dominant negative NF-Ya expression plasmid NF-YAM29 (0.1 µg, 0.2 µg, 0.3 µg) was cotransfected with 0.2 µg pGL3-5M4, which inhibits <i>Miwi</i>-luciferase activity. d), Over-expression of USF1/2 upregulates <i>Miwi</i>-luciferase activity. pGL3-5M4 (0.2 µg) was cotransfected with 0.2 µg expression plasmids (pCX-USF1 and/or pCX-USF2) into GC-1 or COS7 cells. e), E2 box mutant pGL3-5M4-E2mut (0.2 µg) was cotransfected with 0.2 µg USF1 and/or USF2 expression plasmids (pCX-USF1 and/or pCX-USF2), indicating no increase in luciferase activity. f), The dominant negative USF expression plasmid A-USF (0.1 µg, 0.2 µg, 0.3 µg) was cotransfected with 0.2 µg pGL3-5M4, which inhibits <i>Miwi</i>-luciferase activity. pGL3-basic was employed as a negative control. pRT-TK served as an inner control for transfection efficiency. …”

Activation of the NF-κB, JAK-STAT and TRAF pathways. by Sven Brandau (70736)

“…Gene expression of unstimulated MSCs was set as 1 (reference value). Values ≥ 2.0 are set as a significant increase of gene expression and values≤0.5 are set as a significant decrease of gene expression after LPS stimulation. 2^−ddCT = 2^{−(dCT Target – dCT Reference) LPS stimulated – (dCT Target – dCT Reference)}^unstimulated. …”

Regional ventilation and respiratory system compliance. by Günther Zick (20626)

“…A small increase in C_RS in the dorsal regions (significant in layers 23 and 24) with the decreased C_RS in the ventral regions (significant in layers 1 to 17 and 27 and 28) at time point 3/5. …”

OMT by Jingmin Ou (19669426)

“…OMT was found to significantly increase the apoptosis rate of endothelial cells (ECs) treated with oxidised low-density lipoprotein (ox-LDL), as measured by caspase-3 activity assay and flow cytometry. qRT-PCR results showed that OMT treatment decreased the expression of miR-199a-5p in ECs.Transfection of miR-199a-5p mimics enhanced the apoptotic effect, whereas miR-199a-5p inhibitors attenuated apoptosis, suggesting that miR-199a-5p has a key regulatory role in EC apoptosis. …”

Supplementary Material for: Effect of Heme Oxygenase-1 Deficiency on Glomerular Proteomics by Detsika M.G. (3195288)

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes by Niina Sandholm (134957)

“…In addition to the decrease in the quality of life, DN accounts for a large proportion of the excess mortality associated with type 1 diabetes (T1D). …”

In the remaining proepicardium, <i>α4 integrin</i> expression and cell proliferation are reduced. by Yohei Saito (180130)

“…<p>(A–H, I and K) <i>In situ</i> hybridizations of sagital paraffin serial sections of E9.5 WT and <i>Mab21l2</i> mutant embryos for the transcripts indicated. …”

External effective doses from soil samples due to artificial radionuclides in the Chernobyl Nuclear Power Plant, Minsk and Gomel (Republic of Belarus). by Yasuyuki Taira (305653)

“…</i></p><p>where <i>C</i> is the activity concentration of detected artificial radionuclides (²⁴¹Am, ¹³⁴Cs, ¹³⁷Cs and ⁶⁰Co; halh-life > 1y) (kBq/m²; calculated from radionuclide concentration in Bq/kg and collected areas of soils (0–5 cm)), <i>D_ext</i> is the dose conversion coefficient as kerma-rate in air at 1 m above ground per unit activity per unit area ((µGy/h)/(kBq/m²) for detected artificial radionuclides with the value of relaxation mass per unit area 10 g/cm² (ICRU 1994)), <i>f</i> is the unit conversion coefficient (0.7 Sv/Gy (UNSCEAR 2000)), <i>s</i> is the decrease in the coefficient by a shielding factor against exposure with gamma rays from a deposit at 1 m above ground (0.7 under the condition of usual land (IAEA-TECDOC-1162)).…”

Worm infestations and development of autoimmunity in children – The ABIS study by Johnny Ludvigsson (167260)

“…We found no differences in incidence of worm infestations at 1, 5 or 8 years of age between children who developed autoimmune disease(s) or healthy controls. …”

<i>Per1</i> mutation enhances masking responses in mice by Nemanja Milićević (7303721)

“…In mice, high illumination levels decrease activity, i.e. negative masking occurs. To investigate the role of core circadian clock genes <i>Per1</i> and <i>Per2</i> in masking, we used a 5-day behavioral masking protocol consisting of 3 h pulses of light given in the night at various illuminances (4–5 lux, 20 lux and 200 lux). …”

Hierarchical agglomerative cluster analysis of expression patterns of <i>Danio rerio</i> embryos tothree whole sediments and sediment extracts and 11 substances. by Kerstin Bluhm (507637)

“…The cells are coloured according to the fold-change of a gene under a certain treatment. Blue segments represent genes with a strong decrease in the abundance of the corresponding transcript, red segments represent genes with a strong increase in the abundance of the corresponding transcript and green segments denote unaffected genes.…”

Experimental and Modeling Study on Ignition Delay Times of Dimethyl Ether/Propane/Oxygen/Argon Mixtures at 20 bar by Erjiang Hu (1286775)

“…Ignition delay times of dimethyl ether (DME)/propane/oxygen/argon mixtures at a pressure of 20 bar were measured in a shock tube at different DME blending ratios (0, 20, 50, 80, and 100%), equivalence ratios (0.5, 1.0 and 2.0), and temperatures (1100–1500 K). …”

Transfer in Rule-Based Category Learning Depends on the Training Task - Fig 4 by Florian Kattner (839540)

“…Individual <i>t</i>-statistics (low power) testing for a significant decrease in performance from the end of training to the initial transfer phase.…”

Experimental and Modeling Study on Ignition Delay Times of Dimethyl Ether/Propane/Oxygen/Argon Mixtures at 20 bar by Erjiang Hu (1286775)

“…Ignition delay times of dimethyl ether (DME)/propane/oxygen/argon mixtures at a pressure of 20 bar were measured in a shock tube at different DME blending ratios (0, 20, 50, 80, and 100%), equivalence ratios (0.5, 1.0 and 2.0), and temperatures (1100–1500 K). …”

Effect of oral tranexamic acid for macular edema associated with retinal vein occlusion or diabetes by Masayuki Takeyama (3683638)