Torsional strength decreased with Db/Db genotype. by Devorah M. Natelson (8807576)

Th1 differentiation and IFN-γ secretion are impaired in <i>ccr2</i>^-/- mice during <i>C</i>. <i>muridarum</i> infection. by Shuaini Yang (20670608)

Subjects:

Solvent Entrapment of BI 763963 by Solid Solution Formation by Samruddhi Patil (11523791)

“…Two binary T-w phase diagrams were constructed showing the outline of the solidus and liquidus, where EtOH and IPA are present in the solid phase of BI 763963 at 0.54 and 1.5 wt %, respectively, at equilibrium. Importantly, the solvent solubility of BI 763963 was found to be dependent on the residual solvent level in the solid phase and in the case of EtOH increased by almost 50% at just 1.1 wt % EtOH entrapment. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Kcnk5b activity induces IP₃R-mediated Ca²⁺ release from the ER. by Xiaowen Jiang (8291814)

Data_Sheet_1_Triadin Decrease Impairs the Expression of E-C Coupling Related Proteins in Muscles of MPTP-Induced Parkinson’s Disease Mice.PDF by Min Hyung Seo (10684422)

“…In this study, the expression levels of the components of RYR channels decreased in the quadriceps femoris muscle of MPTP-induced PD mice and in C2C12 cells treated with 1-methyl-4-phenylpyridinium. …”

Structural Studies of the <i>Methylosinus trichosporium</i> OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel by Jason C. Jones (9191264)

“…The kinetics of reaction of O₂ with the diferrous sMMOH:MMOB complex in solution show that use of the MMOB V41R variant decreases the rate constant for O₂ binding >25000-fold without altering the component affinity. …”

Structural Studies of the <i>Methylosinus trichosporium</i> OB3b Soluble Methane Monooxygenase Hydroxylase and Regulatory Component Complex Reveal a Transient Substrate Tunnel by Jason C. Jones (9191264)

“…The kinetics of reaction of O₂ with the diferrous sMMOH:MMOB complex in solution show that use of the MMOB V41R variant decreases the rate constant for O₂ binding >25000-fold without altering the component affinity. …”

Decrease in striatal DA release in D2-cKO mice without changes in DA reuptake kinetics or in striatal surface DAT levels. by Nicolas Giguère (7310270)

<i>Emx1</i>-cKO mice lack the neocortex. by Sathish Venkataramanappa (10331993)

Decreased fetal weight in CrryshRNA mice. by Manu Banadakoppa (9199271)

“…<p>Fetal and placental weights were measured at 17.5 dpc soon after euthanasia (n = 5–7), A) Average fetal weight was significantly reduced (<i>p</i> = 0.048) in CrryshRNA mice compared to control group B) Average placental weight was not different between the two groups C) Fetal-placental weight ratio was significantly decreased (<i>p</i> = 0.045) in Crry shRNA mice compared to control mice.…”

Whole mount in situ hybridization (WISH) for <i>atp6v1e1</i> ohnologs in zebrafish embryos. by Lore Pottie (10994479)

“…Gene expression levels of <i>atp6v1e1b</i> remained normal. Data are expressed as mean ± SD from 5 biological replicates. 2-way ANOVA with Tukey test for multiple comparison. …”

RcbA and RcbB co-operatively decrease motility independent of CaCl₂ concentration. by Shobnom Mustaree (21728815)

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments by Animesh Gopal (18521180)

Silencing of <i>NbNBR1</i> decreases the accumulation of βC1. by Tingting Zhou (163678)

Effects of nuclear hormone treatments on <i>kcnk5b</i>, <i>rcan2</i>, and control genes in pectoral fin buds and adult fins and sufficiency/necessity experiments for <i>rcan2</i>. by Xiaowen Jiang (8291814)

Total number of CHWs in scenario C when model parameters are increased or decreased by 10%. by Clara Champagne (5634644)

RV-C15 replicates in ciliated epithelial cells, leading to decreased CDHR3 levels. by Talita B. Gagliardi (6791720)