DAF-16/FOXO is Required for Locomotory Healthspan and Lifespan Benefits of Genetic Glycolysis Disruption. by Brian Onken (86790)

“…<i>daf-16</i> mutants are documented to have lowered locomotory ability vs. WT later in life [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref091" target="_blank">91</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref092" target="_blank">92</a>]; we note that, although comparison of scores across experiments is not possible due to variation in baseline values, the swimming rate of <i>daf-16(mgDf50)</i> control animals was slightly lower than WT controls on the same day of life (in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.g001" target="_blank">Fig 1C</a>; mean of 46.17 head thrashes/30 sec. for <i>daf-16</i> vs. 52.17 head thrashes/30 sec. for WT on day 10). …”

miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling - Fig 6 by Daijiro Hori (3850915)

γ dorsal neurons show decreased calcium responses to odors. by Wang-Pao Lee (6686372)

DualAG decreased TG synthesis in DIO mice. by Vijay R. More (4532392)

<i>Dmd^mdx</i> rats are characterized by muscle weakness and by a decrease in a spontaneous activity. by Thibaut Larcher (331981)

“…<i>Dmd^mdx</i> rats showed fatigue with a decreased force grip across the five pulls, and significant values are obtained for the two last trials that were reduced to ∼70% when compared to Trial 1. …”

A sorghum (<i>Sorghum bicolor</i>) mutant with altered carbon isotope ratio by Govinda Rizal (729644)

“…A mutant (named Mut33) with a pale phenotype and stunted growth was identified from an EMS treated sorghum M₂ population. The stable carbon isotope analysis of the mutants showed a decrease of ¹³C uptake capacity. …”

Nuclear IP3 buffering decreases Ca+2 signals in the nucleus of triple negative breast cancer cells. by Erika Guimarães (3903541)

Loss of primary cilia and decreased nephron number in mice with Tamoxifen-induced <i>Kif3a</i> deficiency. by Lijun Chi (196000)

“…(D, E) The number of primary cilia (green) is markedly decreased in both SIX2-positive cells (nephrogenic precursors) and in ureteric cells <i>Kif3a™</i> kidney (E, asterisk) compared to WT kidney (D). …”

RNAseq analysis and MSD ELISA of proinflammatory cytokines in WT and AD mice. by David J. Braun (7107692)

The predicted daily catches of adult BPH (±SD) if minimum temperature increases with either 0°C, 1°C or 2°C, and daily precipitation either decreases or increases with 10%. by M. P. Ali (533626)

“…<p>The predicted daily catches of adult BPH (±SD) if minimum temperature increases with either 0°C, 1°C or 2°C, and daily precipitation either decreases or increases with 10%.…”

Severity of cirrhosis associates with a decrease of serum Cer levels. by Georgios Grammatikos (587271)

“…No differences in levels of C16 and C18:1Cer are identified, whereas the most significant decrease is observed in serum C24Cer levels (p<0.001 for all comparisons, 2E). …”

<i>Ngl3</i> deletion in mice decreases birth rate and suppresses postnatal growth, survival, and brain development. by Hyejin Lee (636530)

“…Cb, cerebellum; Ctx, cortex; HE, hematoxylin–eosin; Hp, hippocampus; HT, heterozygous; HT-B, heterozygous, C57BL/6; Hyp, hypothalamus; KO, knockout; KO-B, knockout, C57BL/6; KO-H, knockout, hybrid; MAP2, microtubule associated protein 2; NGL-3, Netrin-G ligand-3; ns, not significant; St, striatum; Th, thalamus; WT, wild-type.…”

Chronic administration of SAHA decreases HDAC4 levels and reduces aggregate load – 1^st trial. by Michal Mielcarek (195209)

Involvement of the inhibition of Stat3-mediated transcription in MK591 treatment-induced decrease in c-Myc levels in C4-2B cells. by Sivalokanathan Sarveswaran (723943)

“…<p>C4-2B cells (~3 x 10⁵ cells per plate) were plated in 60 mm diameter plates and allowed to grow for 48 hours. …”

Mutant channel with deletion of the S10 region has decreased surface expression in a stable HEK293 cell line. by Shumin Bian (191969)

“…Surface to total ratios were obtained by integration of the histograms. There is a 40% decrease in surface protein expression for the HSloΔS10 mutant determined by the surface to total HSlo ratio (+/− SEM, p = 0.032 in two sample t-test .n = 5).…”

Examining the Sensitivity of Global CO₂ Emissions to Trade Restrictions over Multiple Years by Mingxi Du (7522889)

“…Our simulations show that trade restrictions would have decreased global emissions by 6.0%, 5.7%, 5.2%, and 4.7% in 2004, 2007, 2011 and 2014; however, restrictions also drove a relative increase in emission intensity for all years. …”

Examining the Sensitivity of Global CO₂ Emissions to Trade Restrictions over Multiple Years by Mingxi Du (7522889)

“…Our simulations show that trade restrictions would have decreased global emissions by 6.0%, 5.7%, 5.2%, and 4.7% in 2004, 2007, 2011 and 2014; however, restrictions also drove a relative increase in emission intensity for all years. …”

Examining the Sensitivity of Global CO₂ Emissions to Trade Restrictions over Multiple Years by Mingxi Du (7522889)

“…Our simulations show that trade restrictions would have decreased global emissions by 6.0%, 5.7%, 5.2%, and 4.7% in 2004, 2007, 2011 and 2014; however, restrictions also drove a relative increase in emission intensity for all years. …”

Decreasing the number of miR-142-3p binding sites leads to increased virus replication in myeloid cells. by Derek W. Trobaugh (6321476)

Downstream signaling pathways of the Htr2b receptor in the mammary gland are altered by serotonin deficiency. by Jimena Laporta (383836)