Arginine-dependent mRNA destabilization. by Tamar Ben-Zvi (3175077)

“…Putrescine can be produced from ornithine via <i>speC</i> and <i>speF</i> encoding a constitutive and inducible ornithine decarboxylase, respectively or from arginine in two steps via <i>speA</i> and <i>speB</i> encoding arginine decarboxylase agmatine ureohydrolase respectively. …”

Effect of Flu on hepatic ATZ accumulation and hepatic fibrosis in the PiZ mouse model. by Jie Li (15030)

“…The asterisk in panel (D) denotes a statistically significant different decrease in p62 levels, p = 0.0354 and the asterisk in panel (E) denotes a statistically significant increase in LC3II/I ratio, p = 0.0075 in the livers of Flu-treated versus control mice (n = 6 each).…”

Evidence from cell culture retrotransposition assays that MOV10 inhibits insertion of non-LTR retrotransposons. by John L. Goodier (126693)

“…V5-DDX17 (isoform (iso)2, #7), is generated from an abbreviated transcript variant spanning only residues 549 to 729 of the C-terminal region of full-length DDX17 (#6). …”

Image_1_The Effect of Metaphylactic Use of Tildipirosin for the Control of Respiratory Disease in Long-Distance Transported Dairy Calves.pdf by Maria Luiza Celestino (9352070)

“…At 27 days after enrollment, META2 calves had decreased concentrations of haptoglobin, serum amyloid A, and aspartate aminotransferase, compared to CON calves (P < 0.05). …”

Challenge with P. gingivalis W83 Strain Elicits Potent Neutrophil Recruitment and Activation in the Peripheral Blood Compared to the Rbr⁻ Strain by Piotr Mydel (19843)

“…The histograms in the bottom row exhibit a two-fold decrease in CD62L expression for peripheral blood neutrophils collected from (F) W83-challenged mice in comparison to (D) control and (E) the <i>rbr⁻</i> mutant strain–infected animals. …”

SS1 virus preferentially infects cells with increased Ras/ELK signaling. by Weihong Pan (327613)

“…A lower level of inhibition was observed for inhibitor of EGFR, AG1478 (0.5 µM). …”

HIF1α deletion affects <i>in vivo</i> virus growth expansion during acute infection. by Darlah M. López-Rodríguez (8098544)

“…Virus replication was significantly decreased on day 5 (<i>P<0</i>.<i>012</i>) or day 7 <i>(P<0</i>.…”

MMP-9 and MMP-8 levels in protracted ARDS. by Michele Y. F. Kong (346852)

“…B: Decline in MMP-8 levels with ARDS progression. Total MMP-8 decreased with ARDS progression in those who remained intubated for >5 days (n = 25, mean±SEM 1245±343 ng/mg at 48 hrs vs. 537±122 ng/mg at day 6, respectively; *<i>p<0.05</i>).…”

Functional Genetic Variants in <em>DC-SIGNR</em> Are Associated with Mother-to-Child Transmission of HIV-1 by Geneviève Boily-Larouche (152000)

“…The implicated H1 and H3 haplotypes share two single nucleotide polymorphisms (SNPs) in promoter region (p-198A) and intron 2 (int2-180A) that were associated with increased risk of both IU (P = 0.045 and P = 0.003, respectively) and IP (P = 0.025, for int2-180A) HIV-1 infection. …”

<b>Dose-response effects of multiple </b><b><i>Ascaris suum</i></b><b> exposures and their impact on lung protection during larval ascariasis</b> by Chiara Amorim (19560544)

“…The emphasis should be on unraveling potential mechanisms that contribute to the regulation of protection against larval ascariasis. We infected BALB/c mice considering the frequency of exposures: single-exposure - SI; twice-exposures - RE 2x and thrice-exposures - RE 3x, and considering the doses of infection: 25 eggs - RE 25; 250 eggs - RE 250 and 2,500 eggs - RE 2500, followed by infection challenge with 2,500 eggs. …”

Deletion of miR132/212 influences synaptic transmission and plasticity in the neocortex. by Judit Remenyi (178669)

“…Scale bar measures 20 ms and 5 pA. C) Superimposition of corresponding amplitude distributions of mEPSCs recorded in the fl/fl neuron (black) and miR-132/212 KO (grey) neuron. …”

Effect of Ultra-fine Traditional Chinese Medicine Compounds on Regulation of Lipid Metabolism and Reduction in Egg Cholesterol of Laying Hens by Y Song (5161109)

“…The hens in the experimental groups (TCM 1 and TCM 2) were fed with the basal diet supplemented with 1% TCM 1 and 1% TCM 2 respectively over a period of 60 days. …”

Summary of key gene expression changes to ER and Golgi function, vesicular transport, mTOR signalling and autophagy. by Laura E. Cox (251297)

“…Multiple SNAREs and adaptor proteins (VTI1, STX4, AP1B1, AP2A2, AP2S1, AP3D1 and AP4B1), which are required for fusion between vesicles carrying mature proteins and the cell surface, endosomes and lysosomes, are downregulated, predicting impairment in the delivery of proteins throughout the cell (5). …”

File S1 - Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles by Wahyu Surya (458156)

“…The amide I peak centered at 1657 cm⁻¹ (blue) and the Fourier self-deconvolved spectra (red) are shown; (B) CD spectra of integrin TM peptides in DHPC-DMPC bicelles, showing minima at 209 and 222 nm, indicating a high proportion of α-helical form for both peptides; (C) Amide I and amide II regions of integrin TM peptides when bulk water was removed (red) and after D₂O-saturated air exposure (blue). …”

Inhibition of thrombin activity by administration of direct thrombin inhibitor Dabigatran etexilate or recombinant murine APC substantially attenuates leukocyte recruitment and pre... by Julian I. Borissoff (280594)

“…<p>(A) Representative hematoxylin and eosin (H&E)-stained sections of atherosclerotic lesions formed in carotid arteries of TM^Pro/Pro:ApoE^−/− mice, which were assigned to different intervention arms (oral Dabigatran etexilate - 7.5 mg DE/gram chow; i.p. administered bolus doses of recombinant murine APC - 2.5 mg/kg/per every 5 days; or placebo) for a total of 6 weeks after cuff placement around the common carotid arteries (top row). …”

Sizes and lifetimes of clathrin-coated structures forming at the cell surfaces. by Saveez Saffarian (249084)

“…The time series were acquired from Swiss 3T3 stably expressing clathrin LCa-DsRed, or from U373 astrocytes and BSC1 cells stably expressing AP-2 σ2-EGFP. Similar results were obtained from data acquired in two additional Swiss, two additional astrocytes, and two additional BSC1 cells (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000191#pbio.1000191.s004" target="_blank">Figure S4</a>). …”

Data_Sheet_1_Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition.pdf by Mayssa Albouery (8294364)

“…Gut colonization by microbiota of old mice resulted in a significant increase in total monounsaturated fatty acids (MUFA) and a significant decrease in the relative amounts of cholesterol and total polyunsaturated fatty acids (PUFA) in the cortex. …”

Vernalization temperature and maturation point of seed cloves on garlic production and quality by José Magno Queiroz Luz (7528091)

“…The experimental design followed a 3 x 3 factorial scheme: three vernalization temperature ranges (-1 to -3 °C; 1 to 3 °C; and 2 to 4 °C) and three seed clove maturation points (normal, early and late). …”

Acute TTBK1 inhibition reduces tau phosphorylation at disease relevant sites <i>in vivo</i>. by Gregory M. Dillon (8681430)

“…<p>We administered the TTBK1 inhibitor, BIIB-TTBK1i, at 25, 50, and 75mg/kg, five minutes prior to isoflurane-induced hypothermia in 2-month-old, male C57Bl/6 mice (n = 3 mice per dose group). …”

Simulation Code by Calvin Hohn (20458484)

“…Heat treatment at T = 50 °C and 80 °C creates new physical or</p><p dir="ltr">covalent bonds between the caseins, which influence the expansion and stability</p><p dir="ltr">behaviour under gastric conditions. …”