SIRT1 modulates the levels of H4K16ac and γ-H2AX and is in complex with TPX2. by Gernot Neumayer (77179)

“…<p>(A) siRNA-mediated loss of SIRT1 in HeLa cells increases H4K16ac levels and decreases ionizing radiation-dependent γ-H2AX levels when compared to controls. …”

REM sleep deprivation induces endothelial dysfunction and hypertension in middle-aged rats: Roles of the eNOS/NO/cGMP pathway and supplementation with L-arginine by Jiaye Jiang (577910)

“…In addition, one group of rats was given continuous access to L-arginine supplementation (2% in distilled water) for the 5 days before and the 5 days of REM sleep deprivation to reverse sleep deprivation-induced pathological changes. …”

The index of ideality of correlation: QSAR studies of hepatitis C virus NS3/4A protease inhibitors using SMILES descriptors by T. Ghiasi (10910038)

“…The models were developed using CORAL software by using two target functions namely target function 1 (TF1) without applying the index of ideality of correlation (IIC) and target function 2 (TF2) that uses IIC. …”

Results for the unimodal spatial-discrimination task. by Fangfang Hong (11707989)

CD4 and CCR5 utilization efficiency of individual virus. by Yiying Zhang (198443)

Experimental procedure and conditions during the recalibration experiment. by Fangfang Hong (11707989)

Cell death rates decrease cell number and affect cell fraction in organisms with <i>ID.</i> by Yuanxiao Gao (6697547)

Can Volunteer Community Health Workers Decrease Child Morbidity and Mortality in Southwestern Uganda? An Impact Evaluation by Jennifer L. Brenner (191976)

“…Community health worker monthly reports revealed a relative decline of 53% in child deaths (<5 years old), during the first 18 months of intervention. …”

Altered transcriptional profiles in mouse hearts with a <i>Prdm16</i> deletion and analysis of functional pathways. by Ji-One Kang (844616)

Beta-catenin signaling in the E14.5 cortex. by Christopher A. Mutch (243132)

“…<p>(<b>A</b>) This series of images represent rostral, middle, and caudal coronal sections (from left to right) of an E14.5 Axin2-d2EGFP forebrain hemisphere, stained with anti-GFP antibody (green) and DAPI (blue). …”

Figure S5_2 from Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma by Joseph J. Caumanns (15010014)

“…(A) Disease-specific survival of patients (n=70) grouped on ARID1A status, (B) PIK3CA status and (C) ARID1A + PIK3CA status. …”

Doxorubicin Impairs the Insulin-Like Growth Factor-1 System and Causes Insulin-Like Growth Factor-1 Resistance in Cardiomyocytes by Patrizia Fabbi (305756)

“…Since cardiomyocyte apoptosis is implicated in anthracycline cardiotoxicity, we investigated the effects of the anthracycline, doxorubicin, on the IGF-1 system in H9c2 cardiomyocytes.</p><p>Methods and Results</p><p>Besides inducing apoptosis, concentrations of doxorubicin comparable to those observed in patients after bolus infusion (0.1-1 µM) caused a progressive decrease in IGF-1R and increase in IGFBP-3 expression. …”

GAS <i>emm</i> types distribution and dynamic profiles. by Sarrah Boukthir (9867410)

BBG depletes cells of PrPsen and mediates decrease in full-length PrPsen on cell surface. by Yoshifumi Iwamaru (237240)

Decrease in the hemolymph sugar level of hyperglycemic silkworms and increase in Akt phosphorylation in the fat body by human insulin. by Yasuhiko Matsumoto (206628)

KOR-agonist (U50'488) and MOR-agonist (DAMGO) decrease symptoms in OVA-allergic mice. by Swantje C. Duncker (154707)

File S1 - Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1 by Chungang Liu (411563)

Two Different Ways of Stress Release in Supercoiled DNA Minicircles under DNA Nick by Ye-Peng Qiao (15383736)

“…Our simulations show that stress release, characterized by the abrupt decrease in linking number, may be induced by two types of DNA motion depending on the nick position. …”

Two Different Ways of Stress Release in Supercoiled DNA Minicircles under DNA Nick by Ye-Peng Qiao (15383736)

“…Our simulations show that stress release, characterized by the abrupt decrease in linking number, may be induced by two types of DNA motion depending on the nick position. …”

Image_5_Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function.jpg by K. M. Hudock (14369595)