Preventive administration of IP7e reduces the number of macrophages and T lymphocytes infiltrated in the spinal cord of mice with EAE. by Francesca Montarolo (171473)

“…<p>Representative images of coronal sections of the spinal cord of IP7e (B, E, H) and vehicle (A, D, G) –treated EAE mice. The presence of perivascular inflammatory infiltrates (A, B), macrophages (D, E) and T lymphocytes (G, H) are evaluated using respectively Hematoxylin and Eosin staining and immunohistochemistry (IB4+ and CD3+ cells for macrophages and T lymphocytes, respectively) in the spinal cord of IP7e (n = 5) and vehicle (n = 5) -treated EAE mice. …”

Data_Sheet_1_Climate Warming Increased Spring Leaf-Out Variation Across Temperate Trees in China.pdf by Yaru Zhang (484892)

“…We observed a significant decrease of LOV toward higher latitudes (−0.2 ± 0.1 days⋅°N^–1;P < 0.001) across all species. …”

Data_Sheet_1_Current Perspectives on Achieving Pronounced Enteric Methane Mitigation From Ruminant Production.docx by Emilio M. Ungerfeld (5414681)

“…<p>Limiting global warming to 1.5°C above pre-industrial levels by 2050 requires achieving net zero emissions of greenhouse gases by 2050 and a strong decrease in methane (CH₄) emissions. …”

Changes in NK cell receptor expression after coculture with HIV-1-infected MDDC. by Daniel Scott-Algara (44427)

“…<p>(a) Dual-label flow cytometric analysis of NK cell proliferation (decrease in CFSE fluorescence) and NKR expression gated on CD16/CD56⁺CD3⁻ cells. …”

TUNEL staining and cell proliferation in the OB by Haydn M Prosser (40070)

“…Note, the difference in size of the OB at 5 × magnification. Scale bars: 100 µm (A and B); 20 µm (C); 500 µm (E and F).…”

Foxd1DTA mutants have cortical regions devoid of nephron progenitor caps and ureteric branching defects. by Stephanie Hum (520223)

“…<p>A–B: Six2 immunofluorescence staining showed that mutant kidneys (B) had gaps in Six2 expression in the renal cortex compared to the consistent line of nephron progenitor caps in controls (A). …”

<b>Pancreatic</b><b> </b><b>β cell TRAPδ deficiency reduces insulin </b><b>production but improves insulin sensitivity</b> by Jiyun Guo (19439922)

DataSheet1_Saccharomyces cerevisiae surface display of endolysin LysKB317 for control of bacterial contamination in corn ethanol fermentations.PDF by Shao-Yeh Lu (9355095)

“…Yeast surface-expressed endolysin demonstrated an 83.8% decrease in bacterial cell counts compared to a 9.5% decrease in control yeast. …”

Surviving kidney epithelium responds by collective migration. by Aurélien Palmyre (596228)

“…<p>Various kidney GFP transgenics were examined by time lapse confocal microscopy at different developmental stages. (A) Proximal tubule epithelium (ET33d10 transgenic, 2.5 dpf), after segmental ablation of the proximal tubule, shown in 30 min intervals. …”

Quantitative PCR validation of mitochondrial genes. by Kwang H. Choi (121395)

“…A: <i>MAOB</i> (monoamine oxidase B), B: <i>NDUFV1</i> [NADH dehydrogenase (ubiquinone) flavoprotein 1, 51 kDa], C: <i>SLC25A14</i> (mitochondrial uncoupling protein 5), D: <i>TUBB3</i> (tubulin beta-3 chain).…”

Stimulus dependent induction of LTP in BLA principal neurons. by Chenchen Li (341873)

“…<b>B</b>) Stimulation of the EC elicits long term synaptic plasticity in BLA afferents following TBS (n = 6, blue diamonds) and 5×100 Hz (n = 5, red squares), but not 2×100 Hz (n = 8, green triangles). …”

Effect of Auphen on hRBC glycerol permeability. by Ana Paula Martins (164194)

“…<p>(A) Time dependent inhibition of glycerol permeability by 5 µM Auphen. …”

Physiological relevance. by Johannes Fels (149139)

“…After an increase of [K⁺]_e from 5 to 12 mM cortical F-actin and К_cortex decrease. …”

Cerebral vasomotor reactivity in migraine: effect of patent foramen ovale and aerogenic microembolism by Farid Khasiyev (9273491)

DataSheet_1_Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy.pdf by Brigida Boccanegra (11104155)

“…These mechanisms are of interest for potentially targeting multiple steps of pathogenic cascade in Duchenne muscular dystrophy (DMD).</p>Methods<p>Here, we aimed to provide preclinical evidence for potential benefits of GHSs in DMD, via a multidisciplinary in vivo and ex vivo comparison in mdx mice, of two ad hoc synthesized compounds (EP80317 and JMV2894), with a wide but different profile. 4-week-old mdx mice were treated for 8 weeks with EP80317 or JMV2894 (320 µg/kg/d, s.c.).…”

Survivorship comparing different model assumptions and strategies. by Frederick R. Adler (143274)

“…</b> increase variance by a factor of 5 (High variance) or decrease variance by a factor of 5 (Low variance), <b>b.…”

<b>The Influence of Pre-Exposure to Marine Heatwaves on the Critical Thermal Maxima (CT</b>_{<strong>max</strong>}<b>) of Marine Foundation Species</b> by Nathan King (8559951)

“…Following a four-week MHW simulation, individuals were subjected to a CT_max trial, where temperatures were raised by 2°C day^-1 until physiological end-points were reached. …”

Nerve conduction and excitability variables before, during and after ischemia. by Jeannette Hofmeijer (424416)

“…<p>Variables before induction of ischemia are presented as mean values ± standard deviation. Values during and after ischemia are expressed as a percentage of values before ischemia with negative values indicating a decrease and positive values an increase. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”

Characterization of Heterogeneity and Dynamics of Lysis of Single Bacillus subtilis Cells upon Prophage Induction During Spore Germination, Outgrowth, and Vegetative Growth Using R... by Mei-yan Wu (9921201)

“…Major findings of this work are as follows: (i) After addition of xylose to trigger prophage induction, the intensities of Raman spectral bands associated with nucleic acids of single cells in induced cultures gradually fell to zero, in contrast to the much smaller changes in protein band intensities and no changes in nucleic acid bands in uninduced cultures; (ii) the nucleic acid band intensities from an individual induced cell exhibited a rapid decrease, following a long lag period; (iii) after the addition of nutrient-rich medium with xylose, single spores underwent a long period (228 ± 41.4 min) for germination, outgrowth, and vegetative growth, followed by a short period of cell burst in 1.5 ± 0.8 min at a cell length of 8.2 ± 5.5 μm; (iv) the latent time (<i>T</i>_latent) between the addition of xylose and the start of cell burst was heterogeneous in cell populations; however, the period (Δ<i>T</i>_burst) from the latent time to the completion of cell lysis was quite small; (v) in a poor medium with l-alanine alone, addition of xylose caused prophage induction following spore germination but with longer <i>T</i>_latent and Δ<i>T</i>_burst times and without cell elongation; (vi) spontaneous prophage induction and lysis of individual cells from spores in a minimal nutrient medium were observed without xylose addition, and cell length prior to cell lysis was ∼4.1 μm, but spontaneous prophage induction was not observed in a rich medium; (vii) in a rich medium, addition of xylose at a time well after spore germination and outgrowth significantly shortened the average <i>T</i>_latent time. …”