siRNA mediated knockdown of NBS1 decreased the levels of phosphorylated Akt (pAkt Ser-473) and its downstream targets and IR increased the levels of NBS1 and phosphorylated Akt. by Jian-Qiu Wang (419143)

“…</b> Western blot analysis showed that knockdown of NBS1 decreased the phosphorylated levels of Akt, GSK-3β, and Foxo1/3a). …”

Impaired bone formation in <i>Col1a1-Krm2</i> transgenic mice. by Jochen Schulze (365258)

“…(B) Histomorphometric quantification showing that the number of osteoblasts (ObN/BPm, osteoblast number per bone perimeter) is not significantly decreased in sections from transgenic mice. (C) Fluorescent micrographs showing that overall calcein labeling is reduced in vertebral bodies of 6 weeks old female <i>Col1a1-Krm2</i> transgenic mice (top, scale bars, 1 mm), as is the distance between the labeled surfaces at endosteal bone surfaces of the tibia (bottom, scale bars, 20 µm). …”

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition by Naping Hu (2614399)

“…The expressions of α-SMA, collagen-I and fibronectin were decreased in the UUO kidney and HK-2 cells of the HSYA-treatment group. …”

Fructose-1,6-bisphosphate induces non-activated phenotype in fibroblasts. by Henrique Bregolin Dias (3700603)

Age-Related ¹H NMR Characterization of Cerebrospinal Fluid in Newborn and Young Healthy Piglets by Domenico Ventrella (3156003)

“…The concentrations of adenine, tyrosine, leucine, valine, 3-hydroxyvalerate, 3-methyl-2-oxovalerate were found to decrease between P05 and P50, while the concentrations of glutamine, creatinine, methanol, trimethylamine and myo-inositol were found to increase. …”

Length of whole blood clots from different amounts of blood in the in vitro middle cerebral artery model (diameter 3.1 mm). by Jan Víteček (11434774)

Experimental study groups and the number of animals within each. by Harry A. Quigley (695817)

Primary antibodies used for histological studies and Immunoblot. by Harry A. Quigley (695817)

Additional file 1 of Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopula... by Lin Lin (46073)

Image_1_Characterization of a Novel Functional Trimeric Catechol 1,2-Dioxygenase From a Pseudomonas stutzeri Isolated From the Gulf of Mexico.tif by Julieta Rodríguez-Salazar (8931386)

“…Under optimal conditions the k_cat and K_m values were 16.13 s^–1 and 13.2 μM, respectively. To our knowledge, this is the first report describing the characterization of a marine C12DOs from P. stutzeri isolated from the Gulf of Mexico that is active in a trimeric state. …”

S1 data_Hazen Main and Blister 2017 absolute diatom counts from Contrasting the ecological effects of decreasing ice cover versus accelerated glacial melt on the High Arctic's larg... by Neal Michelutti (688828)

Increase of <i>Shigella</i> infection induced by miR-29b-2-5p is dependent on multiple targets. by Ushasree Sunkavalli (3916721)

“…Schematic representation of the UNC5C 3'UTR constructs used for the miRNA binding site reporter assays and of the two identified regions of miR-29b-2-5p complementarity to the UNC5C 3’UTR. …”

Age-specific effects on tissue markers in nonirradiated mice. by Daniel Mathias (709246)

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

An <i>in vivo</i> assessment of the cholesterol-lowering efficacy of <i>Lactobacillus plantarum</i> ECGC 13110402 in normal to mildly hypercholesterolaemic adults by Adele Costabile (346639)

“…Daily ingestion of the active treatment resulted in a statistically significant reduction in LDL-C in volunteers with baseline TC<5mM during the 0–12 week period (13.9%, P = 0.030), a significant reduction in TC in volunteers with baseline TC≥6mM in the 0–6 week period (37.6%, P = 0.045), a significant decrease in TAG (53.9% P = 0.030) and an increase in HDL-C (14.7%, P = 0.007) in the over 60 years population in the 6–12 week period. …”

Multivariable model for percent axon loss. by Harry A. Quigley (695817)

Axon loss by treatment group. by Harry A. Quigley (695817)