Data_Sheet_1_Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome.CSV by Katharine Nichole Holm (10051655)

“…Significant differences in FXTAS relative to control brain predominantly involved decreased abundance of proteins, with the greatest decreases observed for tenascin-C (TNC), cluster of differentiation 38 (CD38), and phosphoserine aminotransferase 1 (PSAT1); proteins typically increased in other neurodegenerative diseases. …”

Image_1_Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome.tiff by Katharine Nichole Holm (10051655)

“…Significant differences in FXTAS relative to control brain predominantly involved decreased abundance of proteins, with the greatest decreases observed for tenascin-C (TNC), cluster of differentiation 38 (CD38), and phosphoserine aminotransferase 1 (PSAT1); proteins typically increased in other neurodegenerative diseases. …”

Image_1_Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome.tiff by Katharine Nichole Holm (10051655)

“…Significant differences in FXTAS relative to control brain predominantly involved decreased abundance of proteins, with the greatest decreases observed for tenascin-C (TNC), cluster of differentiation 38 (CD38), and phosphoserine aminotransferase 1 (PSAT1); proteins typically increased in other neurodegenerative diseases. …”

Data_Sheet_1_Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome.CSV by Katharine Nichole Holm (10051655)

“…Significant differences in FXTAS relative to control brain predominantly involved decreased abundance of proteins, with the greatest decreases observed for tenascin-C (TNC), cluster of differentiation 38 (CD38), and phosphoserine aminotransferase 1 (PSAT1); proteins typically increased in other neurodegenerative diseases. …”

Platelet P-selectin is necessary for keratocyte recovery after corneal epithelial abrasion. by Fong W. Lam (702986)

Anterior central keratocyte recovery is incomplete after corneal epithelial abrasion. by Fong W. Lam (702986)

Recognition of Double Strand Breaks by a Mutator Protein (MU2) in <em>Drosophila melanogaster</em> by Raghuvar Dronamraju (204100)

“…Domain searches indicated that the protein contains an N-terminal FHA domain and a C-terminal tandem BRCT domain. Peptide pull-down studies showed that the BRCT domain interacts with phosphorylated H2Av, while the FHA domain interacts with the complex of MRE11, RAD50, and NBS. …”

Measurement of plasma ACE in SCD. by Pamela L. Brito (12042075)

Table_2_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice by Caroline Sarah Biskup (163085)

“…We tested ATD Moja-De (TRP−) in two strains of mice: C57BL/6J, and BALB/cJ, which are reported to have impaired 5-HT synthesis and a more anxious phenotype relative to other strains of mice. …”

Effect of Two or Six Doses 800 mg of Albendazole Every Two Months on <i>Loa loa</i> Microfilaraemia: A Double Blind, Randomized, Placebo-Controlled Trial by Joseph Kamgno (81039)

“…The percentages of participants with ≥ 50% decrease in LLM from pre-treatment for ≥ 4 months were 53%, 17% and 11% in the 6-dose, 2-dose and placebo treatment arms, respectively. …”

Fig 5 - by Thiago Bezerra Wanderley e Lima (14232350)

Fig 7 - by Thiago Bezerra Wanderley e Lima (14232350)

Transcript and protein expression levels of APOE (A, C), ABCA1 (B, D), LRP1 (E, G) and LRP6 (F, H) in MS and MS9II cells. by Yanlin Wang (110566)

“…Immunoblots and respective histograms validating increased APOE (C) and decreased ABCA1 (D) levels in MS9II cells. …”

Systematic Investigation of Cellular Response and Pleiotropic Effects in Atorvastatin-Treated Liver Cells by MS-Based Proteomics by Haopeng Xiao (1643719)

“…Many lipid-related protein abundances were increased in HepG2 cells treated by atorvastatin, including HMGCR, FDFT, SQLE, and LDLR, while the abundances of proteins involved in cellular response to stress and apoptosis were decreased. …”

Systematic Investigation of Cellular Response and Pleiotropic Effects in Atorvastatin-Treated Liver Cells by MS-Based Proteomics by Haopeng Xiao (1643719)

“…Many lipid-related protein abundances were increased in HepG2 cells treated by atorvastatin, including HMGCR, FDFT, SQLE, and LDLR, while the abundances of proteins involved in cellular response to stress and apoptosis were decreased. …”

Maduramicin Inhibits Proliferation and Induces Apoptosis in Myoblast Cells by Xin Chen (14149)

“…Using mouse myoblasts (C2C12) and human rhabdomyosarcoma (RD and Rh30) cells as an experimental model for myoblasts, here we found that maduramicin inhibited cell proliferation and induced cell death in a concentration-dependent manner. …”

Importance of Energy Level Matching for Bonding in Th³⁺-Am³⁺ Actinide Metallocene Amidinates, (C₅Me₅)₂[ⁱPrNC(Me)N<... by Justin R. Walensky (1472710)

“…The synthesis of a rare trivalent Th³⁺ complex, (C₅Me₅)₂[ⁱPrNC(Me)NⁱPr]Th, initiated a density functional theory analysis on the electronic and molecular structures of trivalent actinide complexes of this type for An = Th, Pa, U, Np, Pu, and Am. …”

DataSheet_1_Effects of Alcohol and Cocaine in a Mutant Mouse Model of Predisposition to Post-Traumatic Stress Disorder.pdf by Eleni Paizanis (302275)

“…The spontaneous chronic consumption of either alcohol or cocaine under a 3-week free-choice progressive paradigm of alcohol (3/6/10%) or cocaine (0.2/0.4/0.6 mg/ml), was assessed in VGV transgenic mice, having full 5-HT_2C receptor editing and displaying PTSD-like behaviors. …”

Transcript and protein expression levels of IDE (A, C), PLAU (B, D), GSK-3β (E, G) and CDK5 (F, H) in MS and MS9II cells. by Yanlin Wang (110566)

“…Immunoblots and respective histograms validating decreased IDE (C) and unchanged uPA (D) levels in MS9II cells. …”