Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i>^−/− cells. …”

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis by Raj Vuppalanchi (458660)

“…In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis.…”

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…(<b>C</b>) LDs, stained with a neutral lipid dye (LipidTOX), are more abundant in pericardial nephrocytes (dashed outlines) of HFD than STD larvae. …”

Trehalose decreased PAN-induced apoptosis in human podocytes. by Yu-Lin Kang (663806)

“…<p>Podocyte were treated with PAN (30 µg/ml) or/and Trehalose (50 mM) for 48 h. (<b>A</b>) Trehalose induced autophagy in PAN-treated human podocytes. …”

Image2_Trained hypertensive rats exhibit decreased transcellular vesicle trafficking, increased tight junctions’ density, restored blood-brain barrier permeability and normalized a... by Vanessa B. Candido (14670266)

TL decreases cell viability in malignant cells dependent of p53 status. by Ajay Kumar (192967)

Basal ubiquitination of GlyT2 in neurons decreases when the pool of free monomeric ubiquitin is reduced. by Jaime de Juan-Sanz (386083)

Systemic inhibition of TGF-β decreases retinal smad2 phosphorylation <i>in vivo</i>. by Tony E. Walshe (269700)

“…Immunohistochemical localization of pp-smad2 in retinas from (B) control (non infected animals) and (C) Ad-null and Ad-sEng-expressing mice (day 7) revealed pp-smad2 staining in nuclei of the ganglion cell layer (arrows) and the INL (arrowheads). sEng expression led to a decrease in the intensity of pp-smad2 staining. …”

The ATR-CHK1 inhibitor AZD6738 decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…Decreased bone estrogen receptor alpha (ERα) was observed in Sirt1^+/Δ compared to WT female mice and was significantly higher in Sirt1 over-expressing C3HT101/2 murine mesenchymal stem cells. …”

Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study by Sérgio Aparecido Cleto (3143949)

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…RP = Regulatory Particle, CP = Core Particle. (C) The chymotrypsin-like activity of 26S proteasomes in whole cell lysates of stationary phase cells (A₆₀₀>5.0) was monitored by Suc-LLVY-AMC cleavage over time on microplate reader (ex. 360nm and em. 465nm). …”

Wild-type SPOP increases, and the prostate cancer-associated SPOP mutants decrease, mitochondria average length. by Xiaofeng Jin (646436)

Effect of specific inhibitors on CYP-mediated CK (50 μM) metabolism in HLMs. by Jian Xiao (253329)

“…<p>Note: Furafylline, tranylcypromine, sulfaphenazole, quinidine, chlormethiazole, ticlopidine, and ketoconazole were used as the specific inhibitors for CYP1A2, CYP2A6, CYP2C9, CYP2D6, CYP2E1, and CYP2C19, respectively. …”

A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population by Victoria L. Herrera (383897)

“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”

Cytokine dependent decrease in vSMC viability after type I NKT cell activation. by Gijs H. M. van Puijvelde (500345)

HvPIN1a localisation is influenced by BFA and its expression is decreased by cytokinin. by Gwendolyn K. Kirschner (5142644)

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... by Shuhei Ikeda (2380180)

Subjects:

rhIL-4 and rhIL-13 decrease LEC proliferation and downregulate expression of Prox-1. by Ira L. Savetsky (749034)