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point decrease » point increase (Expand Search)
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VRK1 overexpression is seen in human breast cancer and is associated with decreased relapse-free survival.
Published 2018“…Data for cancer subtypes are shown in boxes numbered 1–11: 1: benign breast neoplasm (rank 6459, 1.4 fold-change, NS), 2: breast carcinoma (rank 833, 1.5 fold-change, p = 3.83x10<sup>-5</sup>), 3: breast phyllodes tumor (rank 512, 1.2 fold-change, p = 0.002), 4: ductal breast carcinoma in situ (rank 1969, 1.5 fold-change, p = 0.002), 5: invasive breast carcinoma (rank 1060, 1.6 fold-change, p = 1.28x10<sup>-5</sup>), 6: invasive ductal and invasive lobular breast carcinoma (rank 941, 1.5 fold-change, p = 6.76x10<sup>-22</sup>), 7: invasive ductal breast carcinoma (rank 613, 1.5-fold change, p = 2.71x10<sup>-71</sup>), 8: invasive lobular breast carcinoma (rank 947, 1.3 fold-change, p = 3.64x10<sup>-28</sup>), 9: medullary breast carcinoma (rank 400, 1.8 fold-change, p = 3.25x10<sup>-12</sup>), 10: mucinous breast carcinoma (rank 1932, 1.4 fold-change, p = 7.41x10<sup>-10</sup>) and 11: tubular breast carcinoma (rank 1253, 1.4 fold-change, p = 1.24x10<sup>-17</sup>). …”
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The 5’SS motif decreases mRNA stability and promotes nuclear retention.
Published 2015“…Note that the relative level of <i>c-ftz-Δi-V5-His</i> decreases over the first 60 min until 40–50% of the mRNA remains, after which point the ratio is stable. …”
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MMR mutants show decreased mating-type silencing.
Published 2020“…Cells were five-fold serially diluted and then spotted onto SD-ura-leu + 2% glucose (left) or SD-ura-leu + 2% galactose (right) agar plates. …”
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Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons.
Published 2025“…Scale bars same as panel B. <b>D.</b> Quantification of the overall myelin intensity in PFC of both groups shows a clear loss of myelin in the juvenile demyelination group (<i>t test; n = 6/5 mice per group, ***p < 0.001</i>). …”
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