Prediction of late response to DNA damage. by Sohyoung Kim (253617)

“…<p>Simulations were based on the model in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000665#pcbi-1000665-g002" target="_blank">Figure 2-B</a>. One of the kinetic parameter sets derived from OSC1P1 was used for simulation. …”

Video_1_Case report: A Chinese patient with spinocerebellar ataxia finally confirmed as Gerstmann-Sträussler-Scheinker syndrome with P102L mutation.MP4 by Lin Chen (54305)

“…Positron emission tomography–computed tomography (PET–CT) (18F-fluoro-2-deoxy-d-glucose, FDG) images showed mild to moderate decreased glucose metabolism in the left superior parietal lobe and left middle temporal lobe. …”

Effect of an intravitreal injection of 20μg VCP on the photo-oxidative damaged retina. by Nilisha Fernando (4955851)

“…<b>D-F:</b> Retinal expression of <i>Gfap</i>, <i>Ccl2</i> and <i>C3</i> did not significantly change between the VCP and saline groups following photo-oxidative damage (P>0.05). * indicates a statistical significance of P<0.05. …”

Loss of <em>Hairless</em> Confers Susceptibility to UVB-Induced Tumorigenesis via Disruption of NF-kappaB Signaling by Hyunmi Kim (156020)

“…This constitutive activation of NFκB in the <em>Hr</em> mutant epidermis leads to the stimulation a large variety of downstream effectors including the cell cycle regulators cyclin D1 and cyclin E, the anti-apoptosis protein Bcl-2, and the pro-inflammatory protein Cox-2. …”

Energy saving potential analysis applying factory scale energy audit – A case study of food production by Derar, Al Momani

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β-adrenergic stimulation in NF trabeculae (<i>n</i> = 9) vs. failing trabeculae with no hypothyroidism (FNH; <i>n</i> = 9) and failing trabeculae with hypothyroidism (FH; <i>n</i>... by Nancy S. Saad (2615341)

“…<b>(H)</b> NF myocardium showed faster +dF/dt/F_dev and -dF/dt/F_dev throughout the concentration-response protocol compared to both failing groups with significantly faster +dF/dt/F_dev at 0.3 μM and 1 μM and significantly faster -dF/dt/F_dev at 30 nM, 0.1 μM and 1 μM vs. …”

Direct regulation time course dynamics varying the period of . by Luca Cerone (186603)

“…<p>The plots show the response of a gene (red curve) and its average value at stationary regime (red dashed) in the case of direct regulation by a symmetric oscillating transcription factor (black curve) having a period of 3 hrs (A) 1 hr (B) 0.5 hr (C). oscillates with varying amplitude depending on the period of oscillation of . …”

Data_Sheet_1_Total yeast and mold levels in high THC-containing cannabis (Cannabis sativa L.) inflorescences are influenced by genotype, environment, and pre-and post-harvest handl... by Zamir K. Punja (9025130)

“…Under these conditions, the majority of dried commercial cannabis samples contained <1,000–5,000 cfu/g. Our findings indicate that TYM in cannabis inflorescences are the result of a dynamic interaction between genotype, environment, and post-harvest handling methods. …”

Data_Sheet_1_Real-Time Multifrequency MR Elastography of the Human Brain Reveals Rapid Changes in Viscoelasticity in Response to the Valsalva Maneuver.docx by Helge Herthum (10748307)

“…Group mean VM values showed an early overshoot of | G^∗| 2.4 ± 1.2 s after the onset of the maneuver with peak values of 6.7 ± 4.1% above baseline, followed by a continuous increase in stiffness during VM. A second overshoot of | G^∗| occurred 5.5 ± 2.0 s after the end of VM with peak values of 7.4 ± 2.8% above baseline, followed by 25-s sustained recovery until the end of image acquisition. φ was constantly reduced by approximately 2% during the entire VM without noticeable peak values. …”

Data_Sheet_1_Extreme Levels of Ocean Acidification Restructure the Plankton Community and Biogeochemistry of a Temperate Coastal Ecosystem: A Mesocosm Study.docx by Carsten Spisla (6395477)

Alteration of RRM1 expression after gemcitabine exposure in pancreatic cancer cells. by Tomotaka Kato (5916590)

“…The numbers at the bottom indicate the relative intensity of the bands for upper band shifted RRM1 expression after gemcitabine exposure comparting to corresponding controls of original RRM1 intensity with no gemcitabine treatment (normalized by GAPDH). <b>(D)</b> Effects of gemcitabine treatment on RRM1 expression level in PSN1, MIAPaCa2, and Panc1 cells. …”

Table1_Uncovering the clinical relevance of unclassified variants in DNA repair genes: a focus on BRCA negative Tunisian cancer families.xlsx by Maroua Boujemaa (5350577)

“…The pathogenicity of VUSs identified within 26 DNA repair genes was assessed using different in silico prediction tools including SIFT, PolyPhen2, Align-GVGD and VarSEAK. Effects on the 3D structure were evaluated using the stability predictor DynaMut and molecular dynamics simulation with NAMD. …”

Image1_Uncovering the clinical relevance of unclassified variants in DNA repair genes: a focus on BRCA negative Tunisian cancer families.pdf by Maroua Boujemaa (5350577)

“…The pathogenicity of VUSs identified within 26 DNA repair genes was assessed using different in silico prediction tools including SIFT, PolyPhen2, Align-GVGD and VarSEAK. Effects on the 3D structure were evaluated using the stability predictor DynaMut and molecular dynamics simulation with NAMD. …”

Data_Sheet_2_Mechanistic Target of Rapamycin Complex 2 Regulation of the Primary Human Trophoblast Cell Transcriptome.pdf by Fredrick J. Rosario (9692354)

“…In contrast, the protein expression of Osteopontin and SLC5A6 was decreased and positively correlated to mTORC2 signaling in human IUGR placentas. …”

DataSheet_1_Turbulence affects larval vertical swimming in the cold-water coral Lophelia pertusa.pdf by Vilhelm Fagerström (14234933)

“…Previous studies have shown that the planktonic larvae of the cold-water coral Lophelia pertusa in still water swim upwards at a speed of ca. 0.5 mm s^-1 during a pre-competency period of 3–5 weeks. …”

Data_Sheet_1_Ion Channel Targeted Mechanisms of Anti-arrhythmic Chinese Herbal Medicine Xin Su Ning.PDF by Taiyi Wang (6305579)

“…Our main findings are: (1) On ECG recorded in isolated rat, in the presence of XSN the amplitude of R wave was significantly decreased and the amplitude of T wave was increased significantly; (2) XSN blocked hNaV1.5 channel stably transfected cell line in a dose-dependent manner with an IC₅₀ of 0.18 ± 0.02 g/L; and (3) XSN suppresses hERG channels in a dose-dependent manner with an IC₅₀ of 0.34 ± 0.01 g/L. …”

Protein production levels under various conditions by Joe GG Vethanayagam (6252)

“…B. 10% PAGE of cell lysates from BL21(λDE3) containing pJGGV. Arrow indicates proOmpA migration. Lane 1, molecular weight marker; lanes 2 (uninduced) and 3 (induced) are samples from cells immediately after transformation; lanes 4 (uninduced) and 5 (induced) are the same strain after 3 subculturings; lanes 6 (uninduced) and 7 (induced) are BL21(λDE3) retransformed with the plasmid rescued from the strain in lane 4.…”

Table 1_Litter quality outweighs climate in driving grassland root decomposition.docx by Jingjing Yang (119262)

“…With respect to biotic factors, grazing (+7.51%) significantly increased decomposition, whereas vegetated soil (−27.84%), increased plant species richness (−4.99%), increased root litter richness (−5.93%), home-field decomposition (−4.34%), and soil biota exclusion (−10.40%) decreased it.…”

Nutritional Composition, Metabolisable Energy and Total Use of Sunflower Seed Cake for Meat Quail by CN Cordeiro (12652797)

“…For the performance trial, 432 quails were assigned to six treatments (dietary inclusion of 0, 5, 10, 15, 20 and 25% SC) in a CRD with six replicates of 12 birds. …”

Table_1_Turbulence affects larval vertical swimming in the cold-water coral Lophelia pertusa.pdf by Vilhelm Fagerström (14234933)

“…Previous studies have shown that the planktonic larvae of the cold-water coral Lophelia pertusa in still water swim upwards at a speed of ca. 0.5 mm s^-1 during a pre-competency period of 3–5 weeks. …”