Activin expression network at ovulation. by Christopher J. Martyniuk (243374)

“…Red indicates that the gene is increased and green indicates that the gene is decreased. The abbreviations are provided in the supplementary abbreviation list (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059093#pone.0059093.s005" target="_blank">File S5</a>).…”

Effects of SIL treatment on the Notch signaling pathway, mitochondrial apoptotic pathway, and pro-survival factors in HCC cells (24 h). by Song Zhang (180477)

“…<p>Representative Western blot results are shown. SIL treatment decreased Notch1, RBP-Jκ, Hes1, Bcl2, cyclin D1, and survivin expression, and increased Bax expression. …”

Bland-Altman plots of choroid thickness estimated from fundus photographs. by Yusuke Arai (1849039)

“…<p>A: 125, B: 250, C: 500, D: 1,000, and E: 2,548 images. Black dots: Estimated choroidal thickness from validation photographs. …”

Open Field. by Raina D. Pang (345662)

“…<p>A) 5-HTT KO mice show significantly decreased distance traveled throughout the arena in a novel open field. …”

HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells by Tanveer Sharif (329961)

“…Mechanistically, HDAC6 KD in CSCs decreases pluripotency by promoting autophagy, whereas the inhibition of pluripotency via retinoic acid treatment, POU5F1 or autophagy-related gene (<i>ATG7</i> and <i>ATG12</i>) KD in CSCs decreases HDAC6 expression and promotes differentiation. …”

Data Sheet 1_Effects of chili straw on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacteria diversity in sheep.docx by Jinlong Li (388896)

“…Fifty F1 Dorper×Hu lambs (29.58 ± 2.06 kg) were randomly assigned to five groups, fed pelleted feed with 0%, 5%, 10%, 15%, or 20% CS over a 63-day period, including a 7-day pre-test. …”

Data_Sheet_1_Association of folate and vitamin B12 imbalance with adverse pregnancy outcomes among 11,549 pregnant women: An observational cohort study.doc by Xiaosong Yuan (6683027)

“…A higher SFVB12R increased birthweight (β 60.99; 95% CI 29.52–92.45) and was associated with a higher risk of large-for-gestational-age (LGA) newborns (OR 3.08; 95% CI 1.63–5.83); a lower SFVB12R decreased birthweight (β −43.81; 95% CI −75.62, −12.00) and was associated with a lower risk of LGA newborns (OR 0.75; 95% CI 0.56–1.00), and with higher risks of ICP (OR 2.03; 95% CI 1.54–2.67) and pregnancy-induced hypertension (PIH, OR 1.81; 95% CI 1.09–3.00).…”

Data_Sheet_1_Proportion and trend in the age of cigarette smoking initiation among adolescent smoking experiencers aged 13–15 years in 148 countries/territories.doc by Shuhui Xing (14181710)

“…</p>Results<p>Among 99,728 adolescent smoking experiencers aged 13–15 years, the proportions of initiating cigarette smoking when aged ≤ 9 years, 10–11 years, 12–13 years, and 14–15 years were 22.8% (95%CI 21.3–24.4), 18.8% (17.3–20.2), 36.8% (34.5–39.2), and 21.6% (19.9–23.2), respectively. The average age of cigarette smoking initiation decreased by 0.44 years per 5 calendar-years averagely in 17 (11.5%) of 148 countries, was unchanged in 95 (64.2%) countries, and increased by 0.38 years per 5 calendar-years averagely in 36 (24.3%) countries. …”

Determining the cell type associated with increased collagen production in Mx-cKO mice. by Nina Kawelke (194831)

“…Experiments shown in panels C–F were performed in Mx-cKO mice lacking fibronectin in both hepatocytes and stellate cells to determine which cell type is involved in increased matrix production (shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028181#pone-0028181-g002" target="_blank">figures 2D and 2E</a>). <b><u>Experiments in Alb-cKO mice:</u></b> (<b>A</b>) ELISA for circulating fibronectin shows that deletion of fibronectin in hepatocytes only by using the albumin promoter to drive cre expression (Alb-cKO) results in decreased circulating fibronectin levels in Alb-cKO mice. …”

Interactions between Notch and Wnt signaling during the activation of Müller cells. by Carolina Beltrame Del Debbio (243080)

“…The proportion of SP cells increased to 0.5% in retinal explants treated with Jag1+Wnt3a (<b>D</b>), which was decreased to 0.1% (<b>E</b>) when DAPT was added to the culture, suggesting a synergistic interaction between Notch and Wnt signaling in the activation of SP cell phenotype in Müller cells (<b>F</b>).…”

Attenuated transcription for <i>Hox</i> genes moved towards the centromeric end of the cluster. by Patrick Tschopp (266480)

“…<p>Expression patterns of <i>Hoxd3</i>, <i>Hoxd4</i> and <i>Hoxd9</i> in embryos carrying deletions in 5′ of these genes. Schemes and colors are as for <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000398#pgen-1000398-g003" target="_blank">Figure 3</a>. …”

DataSheet1_Phyllosphere bacterial community and metabolomic analysis revealed the mechanism of Cd tolerance in the bryophyte Tortella tortuosa (Hedw.) Limpr.docx by Yongqi Zhu (11733367)

“…</p>Results<p>The results showed that the maximum Cd absorption capacity of T. tortuosa was 5.0135 mg·kg^-1. The contents of leaf chlorophyll a (Chl a) and chlorophyll b (Chl b) in T. tortuosa decreased (p < 0.05) with the increase of Cd concentration. …”

Measuring intracellular viscosity. by Kelly Aubertin (502991)

“…For these two examples, the viscosity around the observed chain slightly increased after treatment, from </p><p></p><p></p><p><mn>0.11</mn><mo>±</mo><mn>0.01</mn> Pa.s</p><p></p><p></p>to0.18±0.03 Pa.s Pa.s in the mTHPC case, and from <p></p><p></p><p><mn>0.25</mn><mo>±</mo><mn>0.05</mn> Pa.s</p><p></p><p></p>to <p></p><p></p><p><mn>0.55</mn><mo>±</mo><mn>0.04</mn> Pa.s</p><p></p><p></p>in the TPCS2a case. (B) Mean viscosity (averaged over 25 independent measurements at least) is shown for each condition (for unlabeled control cells, for unlabeled cells exposed for 20s, for unlabeled cells treated with nocodazole (10µM, 30min), for cells treated with m-THPC (without exposition, or exposed for 1s and 5s), for cells treated with TPCS2a (without exposition, or exposed for 1s, 5s, and 20s). …”

Revisits, readmissions, and outcomes for pediatric traumatic brain injury in California, 2005-2014 by Renee Y. Hsia (8357220)

“…Population growth adjusted TBI visits increased by 5.6% while those for Other Trauma decreased by 40.7%. …”

Developmental expression and differentiation-related neuron-specific splicing of (Mtss1) in normal and transformed cerebellar cells-2 by Alexander Glassmann (38448)

“…Upon induction of differentiation with increasing doses of retinoic acid (0.1, 0.5 and 1.0 μM for 4 days), the intensity of the band indicative of usage of exon 12 gradually decreases, whereas that indicative of exon 12a remains unchanged, i.e. there is a relative shift towards the latter. …”

Sequence Homology at the Breakpoint and Clinical Phenotype of Mitochondrial DNA Deletion Syndromes by Bekim Sadikovic (56562)

“…In conclusion, sequence homology at the deletion flanking regions is a consistent feature of mtDNA deletions. Decreased levels of sequence homology and increased levels of deletion mutant heteroplasmy appear to correlate with earlier onset and more severe disease with multisystem involvement.…”

Estimation of actomyosin active force maintained by tropomyosin and troponin complex under vertical forces in the <i>in vitro</i> motility assay system by Shuya Ishii (4840320)

“…We find that the angle-corrected force per unit filament length in the active condition (pCa = 5.0) decreases as the angle between the filament and the glass surface increases; i.e. as the force in the vertical direction increases. …”

Understanding the determinants of maternal mortality: An observational study using the Indonesian Population Census by Lisa Cameron (636941)

“…</p><p>Conclusion</p><p>Indonesia has employed a strategy over the past several decades of increasing the supply of midwives as a way of decreasing maternal mortality. …”

Table_1_Association of thyroid function, within the euthyroid range, with cardiovascular risk: The EPIPorto study.docx by João Sérgio Neves (5772401)

“…We aimed to evaluate the association between thyroid function levels within the euthyroid range and cardiovascular risk in a population-based cohort.</p>Methods<p>Eight hundred thirty-five subjects aged ≥45 years from the EPIPorto population-based cohort were included. …”

Replication of the main behavioral patterns of actions and judgments in Experiment 3. by Claire Lugrin (21156528)

“…The blue line and interval represent the mean and its confidence interval across participants. (<b>c, d</b>) Effects of prosocial action Efficiency (pB - b) and score of the worst-off player (min (pA, pB)) on the mean appropriateness judgments of selfish actions rescaled to 0–1 interval (c) and prosocial action rate (d) for the two different task orders: Action 1st in red and judgment 1st in blue. …”