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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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SH-11052 decreases the expression of NF-κB target genes.
Published 2014“…(C) qRT-PCR using TaqMan probes showed that mRNA levels of NF-κB target genes <i>IL8</i> (interleukin-8) (<i>left panel</i>), <i>CCL2</i> (MCP-1) and <i>PTGS2</i> (COX2) (<i>right panel</i>), all induced by TNF-α, were decreased in the presence of <b>2</b> in a dose dependent manner. …”
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GFRα2 expression was dramatically decreased in Runx1 knockout mice.
Published 2013“…GFRα2 and Runx1 decreased concurrently. GFRα1 and GFRα3 increased at 6 d post transection confirming previous rat ISH studies. …”
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The 2lox Lsd1 variant shows decreased binding to known interactors.
Published 2013“…(B) The relative coimmunoprecipitation of the Lsd1 binding partner CoREST was quantitated using ImageJ software. Data represent the mean +/− SD for two independent experiments. (C) Purification of endogenous Lsd1 complexes from MEF lines confirmed a decrease in Lsd1-CoREST interaction in cells expressing the mutant Lsd1. …”
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<i>Cdkl5</i> -/Y mice show an increased freezing time and a decreased distance traveled during the pretone period in the altered context.
Published 2018“…There are no significant differences upon the second and third footshock between two genotypes. (B) <i>Cdkl5</i> -/Y mice show a significantly decreased freezing time during conditioning. …”
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