Image1_Liver Kinase B1 Regulates Remodeling of the Tumor Microenvironment in Triple-Negative Breast Cancer.TIF by Connor T. King (5277398)

“…The proteomic analysis determined that LKB1 overexpression preferentially decreased all major and minor fibril collagens (collagens I, III, V, and XI). …”

Half-toning demonstration of minimum feature spacing. by Daniel J. Cohen (259554)

“…<p>Half-toning was used to produce a 2-D, graded template (left) with the feature density decreasing towards the top of the pattern. …”

Representative NMR spectra of native LDL, oxLDL and eLDL. by Paul Ramm Sander (282481)

“…NMR spectral parameters: 800 MHz spectrometer frequency, 1D-NOESY pulse sequence with water presaturation (noesygppr1d), 7.7 s repetition time, 10 ms mixing time, temperature: 25°C. …”

Synaptophysin levels were significantly increased in spinal cord dorsal horns and were inhibited by roscovitine. by Hong-Hai Zhang (304558)

“…There were no significant differences between the roscovitine and DMSO treated groups treated with saline between 6 h and 3 d post CFA injection (p>0.05). Significant liner correlation was found between synaptophysin expression levels and the PWL thermal threshold (R² = 0.845, p<0.001). …”

Spatial principal components analysis of the distribution of pMAPK labeling in the LAd. by Hadley C. Bergstrom (233247)

“…<p>(A) Photomicrograph (4x magnification) of the LaD with grid overlay. (B) Grid showing the numerical layout of bins (120 <i>µ</i>m²) for the LAd. …”

Effect of detachment procedures on B16F10-luc tumor cells. by Pierre Danhier (180165)

“…<p>OCR values (%O₂/minute) (A, D) of adherent B16F10-luc and detached B16F10-luc. …”

Email activity. by Rachel Curtis-Robles (835328)

“…Peaks generally correspond with a media event featuring Chagas disease and/or kissing bugs: A) July 17/18, Amarillo, Texas newscast and National Public Radio website article; B) July 24, articles about Chagas disease in Virginia; C) July 27, USA Today online article; D) August 2, Arkansas newscast; E) August 11, Cat Channel online article; F) August 18, Lubbock, Texas newscast. …”

Specific inhibition of DNMT1 and DNMT3b induced cellular senescence. by Ah-Young So (221707)

“…(c–d) The expression levels of p16^INK4A and p21^CIP1/WAF1 were confirmed by real-time qPCR (c) and western blot analysis (d).…”

The effects of Hh protein and agonist on vertebrate Smo and Ptc proteins by Maria Frank-Kamenetsky (26382)

“…Blots in (b) and (c) were reprobed with anti-tubulin antibody as a sample loading control. Anti-HA protein blot of cell extracts, fractionated by SDS-polyacrylamide gel electrophoresis, from cells treated with decreasing concentrations of Hh protein (lane 1, 100 nM; lane 2, 50 nM; lane 3, 25 nM; lane 4, 12.5 nM; lane 5, 6.25 nM; lane 6, 3.12 nM), or with vehicle (lane 7), or with increasing concentrations of Hh-Ag 1.2 (agonist; lane 8, 15 nM; lane 9, 31.25 nM; lane 10, 62.5 nM; lane 11, 250 nM; lane 12, 500 nM; lane 13, 1 μM) for 22 hours. …”

Impact of coverage on detection of recombination. by Thibault Corneloup (16293971)

“…These points are then connected to dots that shift their colour to blue and report the number of recombined fragments found when coverage used to detect the recombinants was artificially decreased with tool seqtk to 50%, 40%, 25%, 17.5% or 10% of the initial value. …”

Data_Sheet_1_Investigation of Electrically Evoked Auditory Brainstem Responses to Multi-Pulse Stimulation of High Frequency in Cochlear Implant Users.ZIP by Ali Saeedi (4815120)

“…At a fixed stimulation amplitude, an increasing number of pulses caused increasing wave eV amplitudes up to a certain, subject-dependent number of pulses. …”

Comparative expression analysis of SOX9 and TSHZ3 in the developing ureter. by Elise Martin (409931)

“…(C, F, I) SOX9 expression overlaps with that of TSHZ3 in undifferentiated mesenchymal precursors from early stages whereas SOX9 signal decreases from E15.5 in the cm of the ureter. Broken line in A, B, C, D, E, G, H delineates metanephric mesenchyme (mm), ureter (ur), ureteric epithelium (ue), condensed ureteric mesenchyme (cm), loose ureteric mesenchyme (lm).…”

Table_1_Genetic background determines synaptic phenotypes in Arid1b-mutant mice.XLSX by Hyosang Kim (3410366)

“…In the second paper, in contrast, we did not observe any inhibitory synaptic change in layer 5 mPFC pyramidal neurons, but instead saw decreased excitatory synaptic transmission in layer 2/3 mPFC pyramidal neurons without any inhibitory synaptic change. …”

Image1_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.TIF by Michael A. David (12111687)

“…The in vivo elbow rat (n = 3–10/group) injury model evaluated the effects of orally administered SV and LS at two dosing strategies [i.e., low dose/high frequency/short duration (D1) vs. high dose/low frequency/long duration (D2)] on post-mortem elbow range of motion (via biomechanical testing) as well as capsule fibrosis and cartilage damage (via histopathology). …”

Image3_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.TIF by Michael A. David (12111687)

“…The in vivo elbow rat (n = 3–10/group) injury model evaluated the effects of orally administered SV and LS at two dosing strategies [i.e., low dose/high frequency/short duration (D1) vs. high dose/low frequency/long duration (D2)] on post-mortem elbow range of motion (via biomechanical testing) as well as capsule fibrosis and cartilage damage (via histopathology). …”

DataSheet1_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.DOCX by Michael A. David (12111687)

“…The in vivo elbow rat (n = 3–10/group) injury model evaluated the effects of orally administered SV and LS at two dosing strategies [i.e., low dose/high frequency/short duration (D1) vs. high dose/low frequency/long duration (D2)] on post-mortem elbow range of motion (via biomechanical testing) as well as capsule fibrosis and cartilage damage (via histopathology). …”

Levels of UNC-104 motor in cargo binding variant alleles depends on ubiquitination. by Jitendra Kumar (144555)

“…<p>Ubiquitination is reduced using the mutant <i>uba-1(it129ts)</i> at 22°C. (A1,A2) Anti-UNC-104 western blots. (A1) Total UNC-104 levels increase in <i>unc-104(e1265)</i> upon reducing ubiquitination. …”

Paneth cells are more adherent to laminin than other crypt cells. by Alistair J. Langlands (3164235)

“…Left panels in (A) and (B) indicate the Imaris-rendered surfaces that were used to measure β4 Integrin signal intensity. ± SEM, <i>p</i> < 0.001 (<i>t</i> test), <i>n</i> = 59 Paneth cells (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002491#pbio.1002491.s002" target="_blank">S2 Data</a>.) (D) The number of mouse small intestinal crypt cells attached to laminin-coated surfaces before (Plated) and after (Adherent) shaking decreases (<i>p</i> = 0.0078, Wilcoxon’s paired <i>t</i> test of eight independent experiments, <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002491#pbio.1002491.s003" target="_blank">S3 Data</a>). …”

Table1_Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture.DOCX by Michael A. David (12111687)

“…The in vivo elbow rat (n = 3–10/group) injury model evaluated the effects of orally administered SV and LS at two dosing strategies [i.e., low dose/high frequency/short duration (D1) vs. high dose/low frequency/long duration (D2)] on post-mortem elbow range of motion (via biomechanical testing) as well as capsule fibrosis and cartilage damage (via histopathology). …”

Image_2_mt tRFs, New Players in MELAS Disease.TIF by Salvador Meseguer (834307)

“…Among them are those derived from mt tRNA LeuUUR containing or not the m.3243A>G mutation (mt 5′-tRF LeuUUR-m.3243A>G and mt 5′-tRF LeuUUR), whose expression levels are, respectively, increased and decreased in both MELAS cybrids and fibroblasts. …”