Pol ζ is involved in the majority of error-prone bypass of the 5,6-dihydrouracil-6-sulfonate intermediate of bisulfite-induced cytosine deamination. by Kin Chan (111493)

“…Taken together with previously published biochemical findings <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003149#pgen.1003149-Hayatsu2" target="_blank">[27]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003149#pgen.1003149-Hayakawa1" target="_blank">[48]</a>, these results suggest that the 5,6-dihydrouracil-6-sulfonate intermediate exists in significant quantities <i>in vivo</i> as a consequence of the bisulfite reaction with cytosine. …”

Image5_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…Luciferase activity analysis confirmed heightened NF-ĸB transcriptional activity in FGFR1-overexpressing BEAS-2B cells and BEAS-2B cells treated with 5-Aza-CdR. Additionally, a decrease in methylation levels in the FGFR1 DNA promoter was detected in the serum of asthma patients using the MassARRAY technique.…”

Table_5_Evaluating the effects of antimicrobial drug use on the ecology of antimicrobial resistance and microbial community structure in beef feedlot cattle.csv by Enrique Doster (2926866)

Table_5_Changes in Sea-Ice Protist Diversity With Declining Sea Ice in the Arctic Ocean From the 1980s to 2010s.docx by Haakon Hop (320767)

Table_5_Changes in Sea-Ice Protist Diversity With Declining Sea Ice in the Arctic Ocean From the 1980s to 2010s.docx by Haakon Hop (320767)

Image_5_Evaluating the effects of antimicrobial drug use on the ecology of antimicrobial resistance and microbial community structure in beef feedlot cattle.png by Enrique Doster (2926866)

Image_5_Tetracyclines Diminish In Vitro IFN-γ and IL-17-Producing Adaptive and Innate Immune Cells in Multiple Sclerosis.jpeg by Despoina T. Florou (11759171)

“…The effect of TCs on cell viability and apoptosis was further assessed by flow cytometry with Annexin V staining.</p>Results<p>Both tetracyclines significantly decreased, in a dose dependent manner, IFN-γ production in NKT and CD4⁺ T lymphocytes from MS patients (naïve or treated) stimulated with IL-12/IL-18 but did not decrease IFN-γ producing CD8⁺ T cells from naive MS or treated RRMS patients. …”

DataSheet_1_Increased Expression of Tim-3 Is Associated With Depletion of NKT Cells In SARS-CoV-2 Infection.docx by Jingzhi Yang (830379)

“…However, a decrease of circulating NKT cells has been observed in COVID-19 different stages, of which the underlying mechanism remains to be elucidated. …”

Table 5_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.docx by Ilona Dudka (8857529)

“…</p>Results<p>Benign samples near high-grade tumors (B ISUP 3 + 4) exhibited altered metabolic profiles compared to those close to low-grade tumors (B ISUP 1 + 2). The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. …”

Climate change losses over time. by Oladipo S. Obembe (10987724)

Table_5_Validation of Candidate Gene-Based Markers and Identification of Novel Loci for Thousand-Grain Weight in Spring Bread Wheat.xlsx by Deepmala Sehgal (738391)

“…The reported favorable alleles of TaGs3-D1 and TaTGW6 genes decreased TGW in the datasets. …”

DataSheet_1_25-hydroxyvitamin D3 generates immunomodulatory plasticity in human periodontal ligament-derived mesenchymal stromal cells that is inflammatory context-dependent.docx by Christian Behm (14494487)

“…Inhibition of two of them, prostaglandin E2 and indoleamine-2,3-dioxygenase-1, partially abolished some of the hPDL-MSCs-mediated effects of 25(OH)D₃ on CD4⁺ T lymphocytes.…”

EGF enhances cyclin G2 degradation. by Stefanie Bernaudo (4167634)

“…A dose-dependent decrease of cyclin G2 stability was also observed. …”

Data Sheet 1_Case series: effects of an induced molting protocol using levothyroxine in five captive banded penguins (genus Spheniscus).pdf by Ji-Hyung Park (2244055)

“…The planned levothyroxine dosing protocol was to start with 25 μg/kg PO q24h for 7 d, then increase it gradually to 50 μg/kg PO q24h for the next 7 d and 75 μg/kg PO q24h for 7 d, followed by a gradual decrease to 50 μg/kg PO q24h for 7 d, and 25 μg/kg PO q24h for the final 7 d. …”

Angiogenesis is not defective in LPP1 KO mice. by John Nakayama (701809)

Video_5_Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model.MOV by Mateusz Rytelewski (529418)

Data Sheet 5_Global trends in ambient particulate matter-attributable ischemic heart disease among the elderly (1990–2021).csv by Yangxi Zeng (20710481)

Image5_Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients.tif by Craig P. Collins (14508710)

Systemic and cardiovascular oxidative-nitrative stress. by Bálint Bányai (16384614)

Table_2_The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.XLSX by Yuxiao Zeng (770249)

“…In the present study, using the hEROs as the model, the influences and the mechanisms of PM2.5 on the developing retina were analyzed. It demonstrated that the formation rate of the hERO-derived neural retina (NR) was affected by PM2.5 in a concentration dosage-dependent manner. …”