GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

Reduction of Acc1 protein level decreases glucose-deprived stress granule formation. by Meaghen Rollins (3776008)

An ATM-specific inhibitor decreases HBoV1 infection of HAE-ALI. by Xuefeng Deng (138723)

An ATR-specific inhibitor decreases HBoV1 infection of HAE-ALI. by Xuefeng Deng (138723)

Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver. by Nicole K. Polinski (10947787)

“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”

Homozygous deletion of <i>ERG251</i> leads to the decreased ergosterol accumulation in the absence of FLC and decreased production of toxic dienol in the presence of FLC. by Xin Zhou (54275)

Pan-neuronal <i>dMaf1</i> knockdown decreases <i>dMaf1</i> mRNA level in brains and consistently extends lifespan. by Bowen Xu (5903801)

Ludmila Belayev 12-point scoring between groups. by Guangxiao Ni (19713106)

Subjects:

Cathepsin B and uPAR knockdown decreases Cdk2 activity and the expression of αVβ3 integrin. by Sreelatha Gopinath (238422)

2-CDA decreases PIN 1 protein levels in 7WD10 cells. by Crystal D. Hayes (304487)

“…(B) ImageJ quantitation revealed significantly decreased PIN 1 protein levels at 0.1 mM (39%, p<0.001), at 0.5 µM (30%, p<0.001), 1.0 µM (24%, p<0.001), 5.0 µM (19%, p<0.001) and 10.0 µM (29%, p<0.001) compared to untreated control cells n = 4 in each group. *, p<0.05, **, p<0.01, vs. untreated controls.…”

Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

Subjects:

Fig 5 - by Sheona Isobel Shankland (19976311)

V2 vasopressin receptor abundance. by Sophie Constantin Lütken (689916)

Subjects:

2-ME decreases blood pressure in Sprague Dawley rats. by Weiyu Chen (2216251)

No significant sex differences in Iso-induced decrease of CaD₈₀. by Gregory S. Hoeker (650231)

“…B) Summary data for the decrease in CaD₈₀ (versus baseline values) as a function of the dose of Iso (1, 10, 31.6, 100, 316.2 nM) in the LV base <i>(left)</i> and apex <i>(right)</i> with pacing at 3 (<i>top</i>) and 5.5 Hz (<i>bottom</i>) for female (n = 5) and male (n = 5) hearts. …”

Grb2 silencing decreases phagocytic uptake in RPE cells. by Shameka J. Shelby (279119)

AICAR-activated AMPK decreased SREBP-2 protein levels. by Shudong Liu (733425)

Cumulative effects and geographic distribution of mCHG-decreasing alleles. by Eriko Sasaki (501178)

“…<b>(D)</b> The number of recent transposon insertions [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010345#pgen.1010345.ref022" target="_blank">22</a>] as a function of <i>NRPE1’</i> genotype and the number of mCHG-decreasing alleles. …”

CDDO-Me radioprotection decreases with progressive oncogenic manipulations in HBECs and in a matched NSCLC line. by Mariam El-Ashmawy (678638)

“…Immortalized HBECs with (A) lenti-<i>KRas</i>^V12, (B) lenti-<i>KRas</i>^V12 and sh<i>p53</i> knockdown, and (C) lenti-<i>KRas</i>^V12, sh<i>p53</i>, and <i>myc</i> overexpression. …”

G0S2 stability is decreased in mice lacking ATGL. by Bradlee L. Heckmann (2818306)