Dendritic spine density is reduced exclusively at dystrophic, soluble Aβ and hyperphosphorylated tau accumulating dendrites. by Tobias Bittner (237241)

“…Scale bars: 10 µm (A, G, H) 2 µm (B),</p>…”

Structural analysis of network activity and representation. by A. Ivanenko (9010331)

“…Concurrently, the sparsity (<b>C</b>) and within-sex correlation between FC representations increases (<b>D</b>, red/blue) towards the output layer, while across-sex correlation decreases (<b>D</b>, purple). …”

DEK overexpression in HNSCC cells increases glycolytic end products and TCA cycle intermediates. by Marie C. Matrka (735282)

“…<p>(A-B) PCA scores plot of C-SCC1 generated from normalized bucket intensities showing separation by metabolite presence between C-SCC1 R780 and R-DEK cells (A) and media (B). (C-D) Fold change in bucket intensities for each significantly changed metabolite between R780 and R-DEK cells (C) and media (D) arranged by magnitude of change. …”

Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense by Guoku Hu (186912)

A coarse-grained sensitivity analysis of the effect of drug-induced resistance on treatment outcome. by Erin Angelini (13149930)

“…Case C: low efficacy, low potency (<i>E</i>_<i>SR</i> = 0.02, <i>P</i>_<i>SR</i> = 50). <b>D</b>. Case D: low efficacy, high potency (<i>E</i>_<i>SR</i> = 0.02, <i>P</i>_<i>SR</i> = 10).…”

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition by Francesca Colleoni (278104)

“…Additionally, we studied placentas from sea-level and high-altitude pregnancies. After 4 d at 1% O₂ (1.01 KPa), complex I-supported respiration was 57% and 37% lower, in trophoblast-like JEG3 cells and fibroblasts, respectively, compared with controls cultured at 21% O₂ (21.24 KPa); complex IV-supported respiration was 22% and 30% lower. …”

Pharmacological manipulation of impulsive choice and action in rats. by Nienke Broos (166476)

“…<p>In rats (n = 22), the preference for the large reward in the DRT decreased with increasing delays (A) and amphetamine (0.5 mg/kg) decreased impulsive choice in rats, whereas atomoxetine (1 mg/kg) increased impulsive choice. …”

Effect of Ascophyllum nodosum seaweed extract on post-harvest 'Tommy Atkins’ mangoes by Thiago Anchieta de Melo (5313545)

“…The experiments were carried out in CRD in a 5 x 5 factorial arrangement (concentrations x days of storage) with four replications. …”

Data_Sheet_1_Evaluating the effect of the plan of national syphilis control in controlling the syphilis epidemic in Jiangsu, China 2010–2020.docx by Lingen Shi (11246098)

“…Early syphilis incidence decreased from 21.1 to 8.8 (APC: −7.5, 95%CI: −8.6, −6.5, p < 0.001) per 100,000 people, and congenital syphilis decreased from 63.6 to 4.1 (APC: −14.8, 95%CI: −20.8, −8.4, p < 0.01) per 100,000 newborns from 2010 to 2020. …”

NR4A1 plays a role in expression of Sp-regulated growth promoting and survival genes. by Erik Hedrick (748501)

“…(D) Western blot analysis of tumor lysates from athymic nude mice bearing ACHN xenografts and treated with vehicle (control) or DIM-C-pPhOH (30 mg/kg/d) was also determined. …”

Reduction in cholesterol accumulation induced by ARF6-GTP expression is coupled to endogenous ARF6-GTP levels in NPC mutant fibroblasts. by Jill Kuglin Schweitzer (265172)

“…Arrow points to region where filipin staining no longer overlaps with Lamp1. <i>D</i>, Lysates were prepared from normal (GM05659) and NPC mutant fibroblasts (GM03123, GM17923, GM18436) and subjected to the GST-MT-2 pull-down assay and probed for ARF6. …”

DataSheet_1_Drought responsiveness in six wheat genotypes: identification of stress resistance indicators.pdf by Asma Guizani (16977474)

“…For the drought-sensitive genotypes AG3 and BT, no significant changes were observed in Ψπ⁰, whereas the stomatal conductance (gs) and transpiration rate (E) decreased under stress conditions. These two varieties avoided turgor loss during drought treatment through an accurate stomatal control, resulting in a significant reduction in yield components. …”

E1AF involved in the mouse FAK gene transcription activation in B16F1 cells. by Shufeng Li (48761)

“…FAK promoter activity in B16F1 cells was decreased in the absence of E1AF binding site. (D) Stimulatory effect of E1AF overexpression on FAK promoter activation was prevented in the absence of E1AF binding site. …”

Simulated effects of inhibition loss on binaural tuning of LSO with amplitude overcompensation. by Go Ashida (717470)

“…In panels <b>C</b>, <b>D</b>, <b>F</b>, and <b>G</b>, simulated results for the uncompensated case (gray dot-dashed lines; same data as in the corresponding panels in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009130#pcbi.1009130.g002" target="_blank">Fig 2</a>) and for the perfectly compensated case (thin gray lines; same data as in the corresponding panels in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009130#pcbi.1009130.g003" target="_blank">Fig 3</a>) are shown for comparison; the filled circles show the response for the default number of inputs (M_inh = 8).…”

Domain and intensity of physical activity are associated with metabolic syndrome: A population-based study by José A. Serrano-Sánchez (5653366)

“…This reduction was blunted in those with more than 2 h/d of TV watching time. A PA level of 3 MET-h/d also nullified the risk of MetS in those with low PA and high TV consumption.…”

The effect of DDAH1 on VEGF expression in HUVEC. by Ping Zhang (86495)

“…(C) Overexpression of Ras increased VEGF expression. (D) Treatment with VEGF (50 ng/ml) for 2 days increased proliferation in HUVEC (n = 4, *p<0.05).…”

Mice with AML and MDS show immunophenotypic changes in bone marrow cell composition compared to untreated age-matched control mice. by Brian A. Jonas (61865)

“…Mice with AML and MDS have increased frequency of myeloid cells (Gr-1+ and Mac-1+) and decreased frequency of B-lymphocyte cells (CD19+) compared to control mice (* p<0.05 for controls versus AML by 2-way ANOVA test; ** p<0.05 for controls versus MDS by 2-way ANOVA test). …”

Identification of Nuclear Protein Targets for Six Leukemogenic Tyrosine Kinases Governed by Post-Translational Regulation by Andrew Pierce (156195)

Retinal degeneration phenotype in the Rp1-Q662X mice. A. by Qin Liu (59805)

“…These defects of outer segments were even more evident at 1 month of age, with disorganized membranous whirls in place of outer segments, compared to the well aligned, uniform discs in the control retina (IS, inner segments; OS, outer segments; RPE, retinal pigment epithelium; bars  = 2 µm). <b>D–F.</b> Average rod and cone ERG amplitudes for wild-type (wt/wt), heterozygous (wt/ki) and homozygous (ki/ki) <i>Rp1</i>-Q662X knock-in mice. …”

Unchanged Sho levels in mice with other neurodegenerative illnesses. by Joel C. Watts (195735)

“…(<b>D</b>) Levels of Sho in the brains of Tg4053 mice overexpressing MoPrP inoculated with the MoSP2 strain of protease-sensitive prions were similar to those in age-matched Tg4053 mice inoculated with PBS. …”