P2X4 receptors are enrolled in macrophage inflammatory pathway activation. by Graciana de Azambuja (20707502)

“…<p>A) Gene expression of cd86, arg1, tnf, il1b and p2rx4 in RAW 264.7 macrophages stimulated with LPS, LPS +  IL-4 or PBS (one-way ANOVA, Tukey post hoc; F (2, 8) =  18.80; F (2, 8) =  97.12; F (2, 8) =  251.5; F (2.8) =  84.27), respectively). “*” indicates difference for the PBS group, “+” indicates difference with the IL-4 group. …”

Data_Sheet_1_Coupling Root Diameter With Rooting Depth to Reveal the Heterogeneous Assembly of Root-Associated Bacterial Communities in Soybean.PDF by Wen Luo (513300)

“…Bacterial community assembly was explored across 156 samples from three rhizocompartments (the rhizosphere, rhizoplane, and endosphere) for different diameters (0.0–0.5 mm, 0.5–1.0 mm, 1.0–2.0 mm, and>2.0 mm) and depths (0–5 cm, 5–10 cm, 10–15 cm, and 15–20 cm) of soybean [Glycine max (L.) …”

Effects of Exhaustive Aerobic Exercise on Tryptophan-Kynurenine Metabolism in Trained Athletes - Fig 2 by Barbara Strasser (498431)

“…<p><b>Divergent effects of moderate vs. exhaustive physical exercise on the production of neurotransmitters:</b> Pro-inflammatory cytokines like interferon-y (IFN-y) stimulates several enzymes including [a] indoleamine 2,3-dioxygenase-1 (IDO1), which degrades tryptophan (TRP) and serotonin (5HT), [b] NADPH oxidase (NOx), which produces reactive oxygen species (ROS), and [c] GTP-cyclohydrolase-1 (GCH1), which in human macrophages forms neopterin and in other cells tetrahydrobiopterin (BH₄), the necessary cofactor of several amino acid hydroxylases, including tryptophan 5-hydroxylase (TH) for the production of 5-hydroxytryptamine (5HT, serotonin) and phenylalanine 4-hydroxylase (PAH) for the production of tyrosine, precursor of dopamine, adrenaline and noradrenaline. …”

Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques by Pingchao Li (543008)

“…Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 10⁵ genome copies per ml plasma, SIV^hi) but not in macaques with low viral loads (< 10⁵, SIV^low). …”

COUP-TFII Mutants Are Defective in Decidualization by Isao Kurihara (96147)

“…<div><p>(A–E) <i>PR^Cre/+ COUP-TFII^flox/flox</i> mutants have decidualization failure. …”

hMSC adjunctive therapy failed to alter weight loss or improve survival compared to antiviral therapy alone in experimental severe influenza. by Ilyse Darwish (446378)

“…<p>Eight-week old male C57Bl/6 mice infected with 425 EID₅₀ influenza A/PR/8 virus were administered 2.5 mg/kg oseltamivir in 100 ul ddH2O via gavage, 1×daily for 5 days, beginning day 2 P.I., with or without hMSC administration (5×10⁵ cells) on day 2 P.I. …”

Data_Sheet_1_Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese.ZIP by Ping Xu (122619)

“…<p>The effects of brewers’ spent grain (BSG) diets on the fatty liver deposition and the cecal microbial community were investigated in a total of 320 healthy 5-day-old Landes geese. …”

Data_Sheet_1_Significant Global Yield-Gap Closing Is Possible Without Increasing the Intensity of Environmentally Harmful Nitrogen Losses.docx by Andrew Smerald (12416149)

“…To do this we use the process-based, biogeochemical model LandscapeDNDC to perform global simulations on a 0.5° grid, and evaluate the response of yields and environmental N-losses to changes in N-inputs. …”

Assessing enrichment of known antigens. by Santiago J. Carmona (110864)

“…From the top-left: comparison of different prioritization strategies (ordered by decreasing AUC values): 1) our composite method, 2–9) a number of prioritizations using a single criteria in each case: 2) Codon Usage bias (CAI), 3) Internal repeats, 4) Proteomic evidence of expression, 5) natively unstructured regions, 6) antigenicity (Bepipred), 7) surface localization (GPI), 8) O-Glycosylation, 9) antigenicity (EMBOSS antigenic). p-value, p-value (p-values based on a random permutation test, n = 10,000).…”

Suppressive effect of EP agonists on TGF-β1-induced actin stress fiber formation and migration. by Erina Takai (465811)

“…<p>(A) A549 cells were incubated with TGF-β1 (5 ng/mL) and PGE2 (10 µM), vehicle (methyl acetate), sulprostone, butaprost or PGE1-OH (20 µM) for 12 h. …”

Difference of neural activity among neurons located at recording sites with different movement thresholds for intracortical microstimulation (ICMS). by Noriyuki Higo (364990)

“…The numbers of neurons for ≤5 μA, ≤10 μA, ≤20 μA, ≤30 μA and ≤50 μA were 23, 40, 26, 22, and 22, respectively.…”

Co-culture of wild-type HSC on <i>Tle4</i> null stromal cells impairs long term colony forming ability. by Justin C. Wheat (621068)

“…WT LKS were plated and used in LTC-IC experiments (b) Bar graph showing a dramatic decreased frequency of Sca-1⁺c-Kit⁺ cells after two weeks of co-culture on the stroma from Tle4 null mice with representative flow plots (n = 2 biological replicates per genotype, in triplicate *: <i>P</i></p><p>P<.0001></p><p></p>…”

ActRIIB-Fc robustly accelerated fracture healing and callus mineralization. by Tero Puolakkainen (4247116)

“…There were no significant differences in bone structure between the groups at the two-week time point. (E-I) At four weeks, ActRIIB-Fc treatment resulted in greater increases bone volume/tissue volume, trabecular numbers and volumetric bone mineral density as well as decreased trabecular separation and structural model index-* = p<0.05, ** = p<0.01, *** = p<0.001. n = 8 for PBS 2 weeks, 7 for ActRIIB-Fc 2 weeks, 8 for PBS 4 weeks and 6 for ActRIIB-Fc 4 weeks.…”

Prolonged exposure to oxytocin enhances neuronal but impairs astrocytic and oligodendrocytic differentiation. by Arvind Palanisamy (3159156)

Hybrid wind-diesel-battery system planning considering multiple different wind turbine technologies installation by Rakhshani, E.

“…Furthermore, the total yearly energy generated by diesel generator is decreased by 700 kWh, meaning higher renewable penetration and less emissions.…”
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Table_4_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

Table_1_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

Table_2_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

Table_3_Owner and Cat-Related Risk Factors for Feline Overweight or Obesity.DOCX by Meredith Wall (7272419)

“…Owner-reported body condition scores (BCS) of cats were assessed using images adapted from a 5-point BCS system and categorized as a binary dependent variable: overweight/obese (BCS 4–5) and not overweight (BCS 1–3). …”

miRNAs that are most highly regulated in proliferating CD4⁺ T cells. by Connie L. Sommers (426576)

“…<p>a. miRNAs that are increased (↑) or decreased (↓) in expression more than 5-fold relative to C57BL/6 naïve CD4⁺ T cells. miRNAs that are increased or decreased in LAT Y136F CD4⁺ T cells more than 10-fold are shown in bold. b. miRNAs that are increased (↑) or decreased (↓) in expression more than 5-fold relative to C57BL/6 memory CD4⁺ T cells.…”