Pan-neuronal <i>dMaf1</i> knockdown decreases <i>dMaf1</i> mRNA level in brains and consistently extends lifespan. by Bowen Xu (5903801)

Tamoxifen decreases fasting glucose and improves glucose tolerance in C57Bl/6J mice; Tamoxifen significantly reduces β-cell proliferation in C57Bl/6J mice. by Surl-Hee Ahn (7354373)

Cathepsin B and uPAR knockdown decreases Cdk2 activity and the expression of αVβ3 integrin. by Sreelatha Gopinath (238422)

2-CDA decreases PIN 1 protein levels in 7WD10 cells. by Crystal D. Hayes (304487)

“…(B) ImageJ quantitation revealed significantly decreased PIN 1 protein levels at 0.1 mM (39%, p<0.001), at 0.5 µM (30%, p<0.001), 1.0 µM (24%, p<0.001), 5.0 µM (19%, p<0.001) and 10.0 µM (29%, p<0.001) compared to untreated control cells n = 4 in each group. *, p<0.05, **, p<0.01, vs. untreated controls.…”

SDG decreases iron-induced caspase 3/7 activity in H9c2 cells. by Stephanie Puukila (568109)

Exercise decreased the increased expression of cofilin in the cortex during aging. by Yan Li (23143)

LGP2 deficiency decreases intracellular dsDNA signaling. by Darja Pollpeter (353259)

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

Reversion to susceptibility was consistent with decreasing relative <i>vanA</i> copy number. by Samuel E. Blechman (19506884)

S1 Table - Non-Cellulosic Polysaccharides from Cotton Fibre Are Differently Impacted by Textile Processing by Jean-Luc Runavot (657205)

No significant sex differences in Iso-induced decrease of CaD₈₀. by Gregory S. Hoeker (650231)

“…B) Summary data for the decrease in CaD₈₀ (versus baseline values) as a function of the dose of Iso (1, 10, 31.6, 100, 316.2 nM) in the LV base <i>(left)</i> and apex <i>(right)</i> with pacing at 3 (<i>top</i>) and 5.5 Hz (<i>bottom</i>) for female (n = 5) and male (n = 5) hearts. …”

Cumulative effects and geographic distribution of mCHG-decreasing alleles. by Eriko Sasaki (501178)

“…<b>(D)</b> The number of recent transposon insertions [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010345#pgen.1010345.ref022" target="_blank">22</a>] as a function of <i>NRPE1’</i> genotype and the number of mCHG-decreasing alleles. …”

G0S2 stability is decreased in mice lacking ATGL. by Bradlee L. Heckmann (2818306)

HAI-2 deficiency leads to decreased proliferation of intestinal epithelium. by Roman Szabo (138655)

Loss of Cntnap2 decreases specifically stabilization of new spines. by Amos Gdalyahu (3213810)

“…<p><b>a.</b> From left to right: Chronic imaging through a cranial window of L5 pyramidal neuron. …”

A decreased neurovirulence is observed for rOC/S_G758R variant in 21 day-old BALB/c female mice infected by the intracerebral route. by Alain Le Coupanec (421447)

Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

Subjects:

Berberine inhibits 4-AP-induced glutamate release from rat cerebrocortical nerve terminals; this effect is due to a decrease in vesicular exocytosis. by Tzu-Yu Lin (423761)

“…<p>Glutamate release (+Ca²⁺; A) and Ca²⁺-independent glutamate release (-Ca²⁺; C) was measured under control conditions or in the presence of 10 µM berberine added 10 min prior to the addition of 4-AP. …”

PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Increased BBB disruption, with a decrease in endothelial ZO-1, claudin-5 and occludin, avoided by GM6001. by Saran Feng (345936)