Data Sheet 7_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Data Sheet 1_Large, but short-term, increase in fecal indicator bacteria following extreme flooding from Hurricane Harvey in Houston, TX.docx by Maitreyee Mukherjee (10860393)

“…Due to concerns over fecal contamination of floodwaters, surface water samples were collected at six locations in the southeastern Houston area immediately before and after the hurricane and then every 1 to 2 weeks thereafter over a 2-month period. Total E. coli was enumerated using the IDEXX Quanti-Tray/2000 system. …”

Data Sheet 3_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Electron microscopic Analysis of Hippocampal CA1. by Hiroaki Nabeka (485031)

“…Rat that received a PS18 injection (0.2 mg/kg) after a KA injection (C). Rat that received a PS18 injection (2.0 mg/kg) after a KA injection (D). …”

Data Sheet 4_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Data Sheet 1_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Overexpression of miRNA-584 and miRNA-1290 induced intestinal metaplasia in knock-in mice. A. Determination of miRNA-584 and miRNA-1290 in knock-in mice. by Yongliang Zhu (169964)

“…However, gastric epitheliums were replaced by intestinal metaplasia under light microscopy (×100). <b>D. Determination of </b><b><i>Muc</i></b><b> 2 and </b><b><i>Muc</i></b><b> 6.…”

Data Sheet 1_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Systemic Delivery of Anti-amyloid-β antibody, 6E10, binds differently in brain tissue of amyloid-β expressing TgCRND8 mice vs. that of native wild type mice. by Daniel McLean (108306)

“…(B) PEG-modification of 6E10-⁶⁴Cu (squares) increases brain penetration and can distinguish between TgCRND8 and wild type mice at 10 min (p = 0.001) and 2 h (p = 0.009). (C) PET signal in the brain tissue of TgCRND8 mice decreases over time, whereas the reference tissue (triangles) stays constant, after injection with PEG-modified 6E10. …”

Effect of low cross-linked matrices on osteoblast and osteoclast. by Takako Ida (5787254)

“…(e) Gene expression of <i>Cbfa1/Runx2</i>, type I collagen α2 chain (<i>Col1a2</i>), alkaline phosphatase (<i>Alpl</i>), and osteocalcin (<i>Spp1</i>) significantly increased in these matrices at 3 and 7 days of culture. …”

Alteration of mitochondria-associated apoptotic proteins after cisplatin treatment. by Li Yang (6520)

“…(B) γ-H₂AX and p-p53(pS15) proteins were increased in SiHa shREV3L cells and decreased in ME180 REV3L cells, compared with control cells after cisplatin treatment. …”

Transwell co-culture of RAW 264.7 macrophages induces metastatic gene expression by A549 cells. by Xiuling Li (130607)

“…After 12 h of co-culture with macrophages, the expression of several metastatic genes in control A549 and A549-TPα cells, including MMPs, VEGF and MCP-1 mRNA, were examined by RT-PCR as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054073#s2" target="_blank">Materials and methods</a>. <b>D</b> Co-culture of RAW 264.7 macrophages decreased E-cadherin expression by A549 cells. …”

Supplementary file 1_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.pdf by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Type III IFNs have a lower transcriptional activity compared to type I IFNs. by Kalliopi Pervolaraki (6019664)

“…Data are normalized to TBP and HPRT1 and visualized in a heatmap using R after sorting the fold change of expression in response to type I IFN (β) in decreasing order. (D) Comparison of expression values (log2 (Fold Change)) for all genes induced at the indicated times with type I IFN (β) versus type III IFN (λ1−3). …”

EBNA3C enhances the protein stability of Gemin3. by Qiliang Cai (180057)

“…(C) The protein level of Gemin3 is decreased in BJAB10 and LCL1 cells with EBNA3C stable knockdown. …”

Spontaneous replay switches between multiple environments. by Bastian Pietras (14295598)

“…Nonlocal replay events (NLEs) occur randomly in exclusively one of three environments, while activity in the respective other two is suppressed. The resulting activation sequences of replayed environments—in (A) the activation sequence reads 313123122312321—are analyzed with respect to (C) the transition probabilities between subsequently active environments and (D) sequential activation patterns. …”

MCF7-luc-GFP-mCherry breast tumor response to administration of BPR0L075 observed by bioluminescence. by Li Liu (75607)

“…Control mice show highly reproducible signal, though with significant increase after 24 hours, whereas treated mice show severely decreased signal at the 2 hour time point, though with progressive recovery over 24 hours; (F) The control mice in “E” (dashed lines same symbol designation) were treated with drug on the second day and maximum light emission is plotted. …”

Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of Progression by Heather Pressler (220737)

Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”