Potent Suppression of Kv1.3 Potassium Channel and IL-2 Secretion by Diphenyl Phosphine Oxide-1 in Human T Cells by Ning Zhao (84707)

“…<div><p>Diphenyl phosphine oxide-1 (DPO-1) is a potent Kv1.5 channel inhibitor that has therapeutic potential for the treatment of atrial fibrillation. …”

Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development by Erik Koppes (779493)

“…Using this novel system, we undertook a broad and inclusive approach to identifying key ICRs involved in placental development by correlating loss of imprinted DNA methylation with abnormal placental phenotypes in a mid-gestation window (E12.5-E15.5). …”

Data_Sheet_1_Effects of dietary tryptophan supplementation on rectal temperature, humoral immunity, and cecal microflora composition of heat-stressed broilers.ZIP by Qiufen Li (17056989)

“…Dietary supplementation of Trp decreased the rectal temperature, serum dopamine (DA), EPI, and the levels of CRH and L-kynurenine (p < 0.05), increased the bursal index, the levels of serum IgA, IgM, and 5-HT as well as the relative abundance of Ruminococcus torques group in cecum of heat-stressed broilers (p < 0.05) compared to HS group. …”

Data Sheet 1_Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma.xlsx by Zhaoguang Song (20778602)

“…Moreover, C1 and C2 subtypes had different immune characteristic. Furthermore, a telomere prognostic model including six genes (PDK2, PPARG, MORC4, SP110, TERT and MAP3K5) was established to predict the prognosis of OS patients. …”

Data_Sheet_1_Methacholine-Induced Cough in the Absence of Asthma: Insights From Impulse Oscillometry.pdf by Nilita Sood (9463229)

“…Increased peripheral airway resistance and decreased resonant frequency are associated with a decreased DI Index. …”

YorkU.Grassland.Disturbed.Oct3-2016 by Maryam Yazdi (3113931)

“…Which may be either week 5 = census 1, week 7 = census 2 or week 8 = census 3</p><p><u>Calendar date:</u> its a continuous variable which represents the date that the data collection took place. …”

GPV index. by Maria-Teresa Bosch-Badia (734329)

“…Each one of the five sets of six decreasing points corresponds to each one the five columns under T = 5 for the set of volatilities: 0.10, 0.20, 0.30, 0.40 and 0.50. …”

Different vascular density in humeri of adult <i>Nothosaurus</i> and <i>Cymatosaurus</i> (histotype A). by Nicole Klein (164099)

“…E–F) Samples of <i>Nothosaurus</i> morphotype II humeri in normal light. Vascular density decreases from E) to F). …”

Genes with altered expression in H1.2 knock-down cells. by Mónica Sancho (108376)

“…The nomenclature of genes is shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000227#pgen.1000227.s009" target="_blank">Table S5</a>.…”

Detection of apoptotic cells in the penumbra. by George E. Barreto (195389)

“…<p>(A) Apoptotic cells identified by staining for cleaved caspase 3 show few apoptotic cells in the core and some in the penumbra on day 3, contrasting with a striking increase in apoptotic cells in the core on day 7. …”

Development time and pupal mass. by Mariana Abarca (6792434)

“…<p><b>A)</b> Development time (instar 1 to prepupae; LS means ± SE) and <b>B)</b> pupal mass (mean ± SE) of individuals kept at each of three oscillating temperature regimes (mean ± 5), feeding on either a high quality (green, open circles, kudzu, <i>Pueraria montana</i>) or a low quality (yellow, solid circles, wisteria, <i>Wisteria sinensis</i>) host. …”

Two-dimensional representation of the null model of isolation-by-geographic and temporal distance. by Ron Pinhasi (42876)

“…The LGF model (solid lines) is a variant of the null model, which expects decreased gene flow between contemporaneous Mesolithic (OTUs 9, 10 and 12) and Neolithic (OTUs 4, 5, 6 and 7) populations as a result of cultural barriers imposed by the adoption of agricultural practices.…”

Direct maintenance of acinar cell activity in lacrimal glands (LGs) by orally administrated royal jelly. by Sachiko Inoue (3621764)

“…<p>A: Effects of RJ on decreased tear secretion after postganglionic denervation (PGD; six mice). …”

Congo red staining. by Neel R. Nabar (295865)

“…Aβ Burden was significantly decreased in the Tg PDFM group compared to the control group in the Cortex (57.5%) and the Hippocampus (65.9%) (<i>P<</i>0.05). …”

Phosphorylation model depicting ChREBP response to glucose. by Lisa G. McFerrin (172548)

“…<p>Image adapted from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034803#pone.0034803-Sakiyama1" target="_blank">[29]</a>. 1) In low glucose conditions, sites S140/S196/S626/T666 are phosphorylated and block the NLS and DNA binding activity. 2) Upon glucose stimulation, X5P activates PP2A to dephosphorylate S140/S196 in the cytosol, unblocking the NLS, and allowing ChREBP to enter the nucleus. 3) Nuclear PP2A dephosphorylation of S626/T666 increases DNA binding. 4) Decreased glucose levels increase PKA activity to phosphorylate S140/S196 and shuttle ChREBP back to the cytoplasm.…”

Level of ADL according to ICF staging. by Toshie Manabe (302244)

“…Each item was scored from 1 to 5, with decreasing score values (lower digit items presented difficult conditions).…”

Electrical hearing thresholds. by Verena Scheper (538613)

“…<p>EABR thresholds in AP+ES treated animals (A) increased in 3 and decreased in 3 individuals. …”

Avoiding enzyme overload. by Qaiser Waheed (5095328)

“…All other rate constants are as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0262371#pone.0262371.g007" target="_blank">Fig 7</a>, except that in panel (a) the total amount of enzyme Ez has been increased by one order of magnitude to Ez₀=10⁻⁵, while in panel (b) Ez₀=10⁻⁶, but <i>k</i>₅ and <i>k</i>₆ have been decreased in phase 2 by one order of magnitude to 1.0 and 2.0, respectively. …”

Bioactive Sesquiterpenoids from the Peeled Stems of <i>Syringa pinnatifolia</i> by Ruifei Zhang (3714817)

“…The new sesquiterpenoids represent three skeletons: a rare 2,2,5,9-tetramethylbicyclo[6.3.0]-undecane (<b>1</b>), a humulane-type (<b>2</b>–<b>8</b>), and a caryophyllene-type (<b>9</b>) skeleton. …”

Bioactive Sesquiterpenoids from the Peeled Stems of <i>Syringa pinnatifolia</i> by Ruifei Zhang (3714817)

“…The new sesquiterpenoids represent three skeletons: a rare 2,2,5,9-tetramethylbicyclo[6.3.0]-undecane (<b>1</b>), a humulane-type (<b>2</b>–<b>8</b>), and a caryophyllene-type (<b>9</b>) skeleton. …”