G0S2 stability is decreased in mice lacking ATGL. by Bradlee L. Heckmann (2818306)

HAI-2 deficiency leads to decreased proliferation of intestinal epithelium. by Roman Szabo (138655)

Loss of Cntnap2 decreases specifically stabilization of new spines. by Amos Gdalyahu (3213810)

“…<p><b>a.</b> From left to right: Chronic imaging through a cranial window of L5 pyramidal neuron. …”

A decreased neurovirulence is observed for rOC/S_G758R variant in 21 day-old BALB/c female mice infected by the intracerebral route. by Alain Le Coupanec (421447)

Distinct effects on calcium channel activation of <i>CACNA1I</i> disease-associated amino acid substitutions A398E/V and M1425V/I. by Yousra El Ghaleb (22075892)

Subjects:

Berberine inhibits 4-AP-induced glutamate release from rat cerebrocortical nerve terminals; this effect is due to a decrease in vesicular exocytosis. by Tzu-Yu Lin (423761)

“…<p>Glutamate release (+Ca²⁺; A) and Ca²⁺-independent glutamate release (-Ca²⁺; C) was measured under control conditions or in the presence of 10 µM berberine added 10 min prior to the addition of 4-AP. …”

PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Rac and PKB activities are required for a late phase of cerebellar LTP. by Claire Jackson (362873)

“…Data are mean ± s.e.m. Single sample <i>t</i> test was used to test for a significant increase in mean amplitude of five consecutive pulses at 10 min and 30 min post 1 Hz tetanus; <i>p</i> values were as indicated. …”

Increased BBB disruption, with a decrease in endothelial ZO-1, claudin-5 and occludin, avoided by GM6001. by Saran Feng (345936)

Ibuprofen and diclofenac decrease migration. by Verena Leidgens (815986)

Vectorized siRNA TMPRSS2-ERG IV-SQ impaired tumour growth and restored differentiation <i>in vivo</i>. by Giorgia Urbinati (554921)

“…<b>d.</b> Immunohistochemical analysis revealed a decreased Ki67 positive nuclei only in the tumours treated with NPs siRNA TMPRSS2-ERG IV-SQ. …”

IFN-β signalling pathway stimulation by Poly(I:C) decreased 5’terminally deleted CVB3 RNA forms viral loads, cardiac lesions and mortality in DBA/2J mice. by Domitille Callon (17723936)

Decreased ubiquitination in the dTAK1^K156R mutant. by Merennege Dilan Anush Fernando (525297)

“…Expression vectors encoding dTAK1-V5 or dTAK1^K156R -V5 were transfected along with dTAB2-HA and cMyc-Ub in combinations shown in S2 cells. …”

Data_Sheet_1_Risk of psychological distress by decrease in economic activity, gender, and age due to COVID-19: A multinational study.PDF by Minji Kim (1722313)

“…With 7,090 of female (49.8%), mean age 40.67, 5,734 (12.75%) lost their job and 5,734 (40.26%) suffered from psychological distress.…”

Ibuprofen and diclofenac decrease proliferation. by Verena Leidgens (815986)

“…<p>Proliferation was analyzed using crystal violet staining and results were verified via the CyQuant Direct Cell Proliferation assay in HTZ-349. (A) Starting at 72 h, all ibuprofen concentrations (0.5, 1, 2 mM) resulted in significant reduction of HTZ-349 proliferation (compared to non-treated Ctrl, 95% CI, p < 0.05). 2 mM ibuprofen caused significant proliferation inhibition at 24 h (0.01 > p ≤ 0.001) and 48 h (p < 0.0001). …”

Depletion of PfPKAc in NF54/AP2-G-mScarlet/PKAc cKD parasites leads to a block in merozoite invasion and decreases gametocyte rigidity. by Eva Hitz (10877688)

Success rates increase and number of topics decrease as research activity levels increase. by Mark D. Lindner (748770)

Annual number of outpatient visits in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…<p>In the recurrence group, mean outpatient visits (± standard deviation) decreased from 13.6 ± 3.0 to 11.9 ± 5.0, 8.1 ± 3.9, and 7.8 ± 3.2 at 1, 2, and 3 years postoperatively, respectively (Kruskal-Wallis test, P < 0.001; Dunn’s test, **P < 0.01). …”

SUR1Δ/LDLR^-/- mice have increased fasting glucose levels and impaired glucose tolerance with decreased insulin secretion. by Erika Gurzeler (4781904)

Image4_Immunization of Broiler Chickens With a Killed Chitosan Nanoparticle Salmonella Vaccine Decreases Salmonella Enterica Serovar Enteritidis Load.pdf by Keila Acevedo-Villanueva (10531191)

“…Chitosan nanoparticle (CNP) vaccines can be used to deliver Salmonella antigens orally. We investigated the efficacy of a killed Salmonella CNP vaccine on broilers. …”