The involvement of ERK5 in statin-induced Nrf2 signaling in VSMCs. by Ae-Rang Hwang (4040408)

Subjects:

(A) The temperature sensitive allele of <i>HEM1</i> leads to a significant decrease in the endogenous levels of Cia2 and Mms19. by Ifat Lev (469072)

Stimulation of α2-adrenergic receptors inhibits hippocampal precursor activity and decreases neurogenesis. by Dhanisha J. Jhaveri (577341)

“…<p>(A) Treatment of hippocampal precursor cells with α2-adrenergic receptor agonist at 10 uM significantly decreased neurosphere formation compared to the control. …”

MicroRNA-146a-5p enhances T helper 17 cell differentiation via decreasing a disintegrin and metalloprotease 17 level in primary sjögren’s syndrome by Xiaoyan Wang (8433)

Increased apoptosis and decreased necrosis after BCL-W and BCL2 and autophagy inhibition. by Anatasha C. Crawford (255140)

Continuous passage of SARS-CoV-2_Engl2 in RDV selects for partial resistant populations. by Agnieszka M. Szemiel (10196243)

Subjects:

Effect of CLK2 and SRPK1 KD in HBV-infected dHepaRG cells. by Florentin Pastor (19852287)

TLR2-mediated inhibition of IFN-γ induction of CXCL11 and CIITA decreases expression of protein products. by Sarah A. Benson (371554)

dN/dS ratio for all SARS-CoV-2 open reading frames, ORF1ab and spike for the <i>in vitro</i> continually passaged SARS-CoV-2. by Agnieszka M. Szemiel (10196243)

Subjects:

DN1 and DN2 cells are preferentially increased by TSLP in FTOC and decreased in TSLPRFTOC by Qi Jiang (33521)

Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation. by Arindam P. Ghosh (317870)

“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Downregulation of CHOP decreases apoptosis by activation of ER stress-induced autophagy. by Yan Lei (535846)

MET knockdown decreases EGFR activation and does not influence EGFR expression. by Karolin Ebert (7434713)

Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria by Patricia A. Reis (109310)

Postnatal decrease in PV+ cortical interneurons in Fgfr1 mutant mice. by Karen Müller Smith (613941)

“…Immunostaining for GFAP, Neun, Ng2, Olig2 and GFP in cortex of adult TgFgfr1-GFP mice (<b>D, E, F</b>). …”

Decreased expression of DYRK2 in paraffin-embedded colorectal cancer tissues and advanced colorectal cancer. by Haiyan Yan (2993082)

A decrease in the invasiveness of <i>Candida albicans</i> into Caco-2 cells parallels the differentiation of intestinal epithelial cells. by Marianne Goyer (2550589)

“…D. Caco-2 cell differentiation increased throughout the culture as highlighted by the increase in TEER measurements (Ω.cm²) (full line), which correlated with a decrease in <i>C</i>. …”

Rab7A decreases BST2 cell surface expression and is required for Vpu-induced BST2 cell surface downregulation. by Marina Caillet (198168)

“…<p>(<b>A</b>–<b>B</b>) Rab7A decreases BST2 cell surface expression. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”