Showing 12,281 - 12,300 results of 123,301 for search '(( 2 d decrease ) OR ( 5 ((mean decrease) OR (((nn decrease) OR (a decrease)))) ))', query time: 2.01s Refine Results
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    Comparative Toxicity and Metabolism of N‑Acyl Homologues of Acetaminophen and Its Isomer 3′-Hydroxyacetanilide by Yakov M. Koen (1970593)

    Published 2016
    “…The hepatotoxicity of acetaminophen (APAP) is generally attributed to the formation of a reactive quinoneimine metabolite (NAPQI) that depletes glutathione and covalently binds to hepatocellular proteins. …”
  8. 12288

    Comparative Toxicity and Metabolism of N‑Acyl Homologues of Acetaminophen and Its Isomer 3′-Hydroxyacetanilide by Yakov M. Koen (1970593)

    Published 2016
    “…The hepatotoxicity of acetaminophen (APAP) is generally attributed to the formation of a reactive quinoneimine metabolite (NAPQI) that depletes glutathione and covalently binds to hepatocellular proteins. …”
  9. 12289

    Comparative Toxicity and Metabolism of N‑Acyl Homologues of Acetaminophen and Its Isomer 3′-Hydroxyacetanilide by Yakov M. Koen (1970593)

    Published 2016
    “…The hepatotoxicity of acetaminophen (APAP) is generally attributed to the formation of a reactive quinoneimine metabolite (NAPQI) that depletes glutathione and covalently binds to hepatocellular proteins. …”
  10. 12290

    Comparative Toxicity and Metabolism of N‑Acyl Homologues of Acetaminophen and Its Isomer 3′-Hydroxyacetanilide by Yakov M. Koen (1970593)

    Published 2016
    “…The hepatotoxicity of acetaminophen (APAP) is generally attributed to the formation of a reactive quinoneimine metabolite (NAPQI) that depletes glutathione and covalently binds to hepatocellular proteins. …”
  11. 12291

    Data Sheet 1_Metformin’s effect on metabolic dysfunction-associated steatotic liver disease through the miR-200a-5p and AMPK/SERCA2b pathway.docx by Hang Chen (23866)

    Published 2024
    “…</p>Results<p>In the PA cell model, elevated miR-200a-5p and lipid metabolism gene mRNA levels were observed, with decreased AMPK and SERCA2b protein levels. miR-200a-5p mimic reduced AMPK and SERCA2b expression. …”
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    Poly(I:C) Induces Antiviral Immune Responses in Japanese Flounder (<i>Paralichthys olivaceus</i>) That Require TLR3 and MDA5 and Is Negatively Regulated by Myd88 by Zhi-xia Zhou (660057)

    Published 2014
    “…Taken together, these results indicate that poly(I:C) is an immunostimulant with antiviral potential, and that the immune response of poly(I:C) requires TLR3 and MDA5 and is negatively regulated by Myd88 in a manner not involving NK-κB. …”
  14. 12294

    Simulated response to block of K<sub>ATP</sub> channel in type 2 diabetes (T2D). by Leonid E. Fridlyand (2636968)

    Published 2016
    “…T2D conditions were simulated by a decrease of the coefficient that is responsible for glucose dependent saturated ATP/ADP ratio (ATD<sub>m</sub>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152869#pone.0152869.e004" target="_blank">Eq 4</a>). …”
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    Schematic of how Rh5/6 pathway and IR21a/93a/25a pathway function in the transition of thermopreference in <i>Drosophila</i> larvae. by Jordan J. Tyrrell (10535989)

    Published 2021
    “…At the late third instar, expression of IR21a, IR93a and IR25a is decreased and thus insufficient to drive aversion to 18°C.…”
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    Expression of cytokines by CD3+ infiltration in PDAC. by Gerik W. Tushoski-Alemán (17951809)

    Published 2024
    “…(D) Principal component analysis plot of inflammatory signatures in different tissues, PCA was performed using 31 analytes, as 10 analytes (G-CSF, IL-9,IL-1B,IL-2,IL-3,IL-4,IL-5,MIP-1A,RANTES and TNFB) had limited detection across our patient cohort. …”