Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

“…The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”

shRNA-mediated knockdown of syntaxin-4 (Syn4) decreases expression of KCa2.3 at the plasma membrane (PM) in HeLa cells. by Claudia A. Bertuccio (309866)

“…Knockdown of Syn4 resulted in a decreased PM expression of KCa2.3 (top blot and panel <b>(B)</b>), whereas total KCa2.3 expression was unaffected (middle blot and panel <b>(C)</b>). …”

Absence of PML decreases the co-localization of DAXX and ATRX but not HIRA and UBN1 with latent/quiescent HSV-1 genomes. by Camille Cohen (2440810)

Relative Aggrecan mRNA expression levels, as measured by qPCR, in lentiviral-transduced control cells and 5 AggKD cell lines confirm decreased Aggrecan expression in the AggKD cell... by Juanita K. Hodax (6848540)

Drop point and rebound rounds^a effects for groups in the empirical and simulated data. by Daniel B. Shank (709756)

Fig 5 - by Jens Panse (350046)

<i>Cbp</i> inhibition decreases hypothalamic glycolytic markers. by Cesar L. Moreno (3341927)

Coordinates of A_i and B_i points in cylindrical coordinate system. by Weiliang Zhang (11231646)

Expression and stability of EspA are decreased in the absence of <i>escA.</i> by Ching-Nan Lin (508587)

Inducible expression of DTA in nestin-lineage stem/progenitor cells decreases the number of Ki67+ and DCX+ cells 12 days (d) post-tamoxifen (TAM), but DCX+ cell number is normalize... by Sanghee Yun (450232)

Hydroxyl Defects in LiFePO₄ Cathode Material: DFT+<i>U</i> and an Experimental Study by Dmitry A. Aksyonov (4918594)

“…The presence of D (H) at both Li and P sites for hydrothermally synthesized deuterium-enriched LiFePO₄ is confirmed by joint X-ray and neutron powder diffraction structure refinement at 5 K that also reveals a strong deficiency of P of 6%. …”

Summary of metabolic analysis of <i>Opn5</i>^<i>cre</i><i>; Gnas</i>^<i>+/+</i> and <i>Opn5</i>^<i>cre</i><i>; Gnas</i>^<i>fl/fl</i> mice by... by Kevin D. Gaitonde (15411707)

Subjects:

The decrease of ULK1 expression by miR-17-5p from BCG infection. by Xiangguo Duan (423329)

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

Subjects:

TG mice hearts show decreased ISO response. by Mayilvahanan Shanmugam (691549)

Effect of 5-HTR blockade on error pattern in the reward-size task. by Yukiko Hori (299784)

Effect of 5-HTR blockade on reaction time in the reward-size task. by Yukiko Hori (299784)

Effects of TGF-β1 on the expression of fibrosis indicators in HBdSMCs and the effects of MEL on the expression of fibrosis indicators in HBdSMCs induced by TGF-β1. by Yang Zhang (30734)

<i>NAB3</i> reduces the level of <i>IMD2</i> CUT terminator readthrough product from a reporter and native <i>IMD2</i> CUT and readthrough RNA, but <i>NAB3</i> does not significant... by Milo B. Fasken (659389)

“…As a control, <i>AIR1</i> significantly decreases Pol II occupancy downstream of the <i>IMD2</i> CUT in <i>air1-C178R air2</i>Δ cells at Primer Pair 4 and 5 positions compared to <i>air1/2</i> cells containing vector alone (<i>p</i>-value ≤ 0.05), indicating that Air1 significantly affects termination and suggesting that <i>air1/2</i> cells have a termination defect. …”

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)