Phase 1 study to evaluate the effects of rifampin or itraconazole on the pharmacokinetics of limertinib (ASK120067), a novel mutant-selective inhibitor of the epidermal growth fact... by Bei Cao (141848)

The overall structure of the device. by Xueting Ma (390540)

Mitochondrial single-stranded DNA binding protein novel <i>de novo SSBP1</i> mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, K... by Margaret A. Gustafson (2138056)

“…Size exclusion chromatography of p.E27K SSBP1 revealed it remains a stable tetramer. However, differential scanning fluorimetry demonstrated p.E27K SSBP1 relative to wild type had modestly decreased thermostability. …”

Concentration-dependent activation and inhibition of hSGLT1 measured by membrane potential-dependent changes in fluorescence. by R. Kyle Palmer (20284957)

DataSheet1_Magnesium Isoglycyrrhizinate Ameliorates Concanavalin A-Induced Liver Injury by Inhibiting Autophagy.docx by Zihao Fan (9502112)

“…In vitro experiments also showed that MgIG reduced ConA-induced hepatocyte death but did not decrease hepatocyte apoptosis by inhibiting autophagy.…”

Table1_Integrated virtual screening and in vitro studies for exploring the mechanism of triterpenoids in Chebulae Fructus alleviating mesaconitine-induced cardiotoxicity via TRPV1... by Liangliang Song (5391836)

“…Then three triterpenoids were selected to verify whether the triterpenoids had the effect of lowering the cardiotoxicity of MA using H9c2 cells combined with MTT, Hoechst 33258, and JC-1. …”

Expression of CPE-ΔN in embryos, embryonic neurons and adult brain. by Xiao-Yan Qin (666512)

“…N = 3. D. Representative Western blot (N = 3) showing the expression of CPE-ΔN and CPE from hippocampus (H) (lanes: 2, 4, 6, 8) and cortex (C) (lanes 3, 5, 7, 9) of mice at PN1, 3, 6 and 12 weeks of age and positive control (Ctrl. using HCC cells transduced with cpe-<i>ΔN</i> construct) (lane 1), probed with mouse monoclonal antibody. * denotes non-specific band.…”

Insights into the Catalytic Mechanism and Selectivity of <i>S</i>‑Adenosyl Methionine (SAM)-Dependent Fluorinase toward Carbon–Halogen Bond Formation by Néstor Gutiérrez-Sánchez (21606132)

“…Therefore, as the proton affinity of the nucleophile decreases, the interaction between the nucleophile and SAM results in a higher reaction barrier.…”

Insights into the Catalytic Mechanism and Selectivity of <i>S</i>‑Adenosyl Methionine (SAM)-Dependent Fluorinase toward Carbon–Halogen Bond Formation by Néstor Gutiérrez-Sánchez (21606132)

“…Therefore, as the proton affinity of the nucleophile decreases, the interaction between the nucleophile and SAM results in a higher reaction barrier.…”

Insights into the Catalytic Mechanism and Selectivity of <i>S</i>‑Adenosyl Methionine (SAM)-Dependent Fluorinase toward Carbon–Halogen Bond Formation by Néstor Gutiérrez-Sánchez (21606132)

“…Therefore, as the proton affinity of the nucleophile decreases, the interaction between the nucleophile and SAM results in a higher reaction barrier.…”

Insights into the Catalytic Mechanism and Selectivity of <i>S</i>‑Adenosyl Methionine (SAM)-Dependent Fluorinase toward Carbon–Halogen Bond Formation by Néstor Gutiérrez-Sánchez (21606132)

“…Therefore, as the proton affinity of the nucleophile decreases, the interaction between the nucleophile and SAM results in a higher reaction barrier.…”

Activation of the IL-2 receptor is associated with induction of JAK/STAT protein expression. by Arnold H. Zea (411800)

“…N = 3 in individual groups. (D) Nuclear STAT 5a protein expression in podocytes was significantly decreased at both time points with IL-2 stimulation (*, P<0.0001) compared to unstimulated podocytes. …”

Odds ratios of switching for student attributes. by Jessica Ellis (3154071)

S1 Data - by Megumi Sato (4116994)

“…The decreased expression of <i>CLB1</i> by the <i>puf5Δ</i> mutation caused a severe growth defect of the <i>puf5Δ clb2Δ</i> double mutant. …”

RBP2 activates HIF-1α via the PI3K/Akt signaling pathway. by Lei Qi (173882)

“…<p>(A) Silencing RBP2 expression in H1975 cells significantly decreased the phosphorylation of Akt, and the forced expression of RBP2 in SK-MES-1 cells increased the activity of Akt. …”

Supplemental Tables for "Hypoxia-inducible factor 1alpha is required to establish the larval glycolytic program in <i>Drosophila melanogaster</i>" by Jason Tennessen (18762937)

Edaravone inhibits neuronal ferroptosis and alleviates acute Central nervous system injury induced by diquat <i>via</i> enhancement of METTL14-mediated m6A methylation of Aldh1l1 by Liaozhang Wu (8371008)

CDK2/Speedy A localization in <i>Cdk2</i>^{<i>−/−</i>} and <i>Speedy A</i>^{<i>−/−</i>} spermatocytes. by Nathan Palmer (264897)

“…<p>Chromosome spread preparations from adult (postnatal day 40) testes immunostained with CDK2 (green) and Speedy A (red) in conjunction with SYCP3 (blue) are shown for <i>Cdk2</i>^{<i>−/−</i>} (A–C) and <i>Speedy A</i>^{<i>−/−</i>} (D–F) spermatocytes for selected stages of meiotic prophase I. …”

Table_2_Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates.docx by Ronni A. G. da Silva (8152626)

Table_2_Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates.docx by Ronni A. G. da Silva (8152626)