datasheet1_Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome.zip by Chengcong Wei (10077199)

“…The expression of endogenous RVD1 was decreased whereas A20 and NLRP3 levels were increased after SAH. …”

image1_Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome.jpg by Chengcong Wei (10077199)

“…The expression of endogenous RVD1 was decreased whereas A20 and NLRP3 levels were increased after SAH. …”

RhoA gene expression and activity are impacted with increased intracellular 5HT. by Celeste M. Sheftel (9557588)

“…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …”

m⁶A mRNA methylation controls autophagy and adipogenesis by targeting <i>Atg5</i> and <i>Atg7</i> by Xinxia Wang (301455)

“…Mechanistically, knockdown of FTO, a well-known m⁶A demethylase, decreased the expression of ATG5 and ATG7, leading to attenuation of autophagosome formation, thereby inhibiting autophagy and adipogenesis. …”

DataSheet1_Vitamin D supplementation is effective for olanzapine-induced dyslipidemia.docx by Zijian Zhou (1449097)

“…Consequently, the expression of cholesterol-biosynthesis-related genes was reduced in calcifediol- and calcitriol-treated C2C12 cells, which was likely to be mediated by activating the vitamin D receptor that subsequently inhibited the cholesterol biosynthesis process via insulin-induced gene 2 regulation. …”

Effect of RAC1b overexpression on the subcellular location of NF-kB-p65 subunit. by Márcia Faria (3779359)

Table_2_Decreased Functional Connectivities of Low-Degree Level Rich Club Organization and Caudate in Post-stroke Cognitive Impairment Based on Resting-State fMRI and Radiomics Fea... by Guofu Miao (11271528)

“…The feeder and local connections of significantly between-group difference were positively related to MMSE and MoCA scores, primarily distributed in the sensorimotor network (SMN) and visual network (VN) in hPSCI, SN, and DMN in iPSCI. Additionally, decreased local connections and low-degree ϕ_norm(k) were correlated to 3D shape features and first-order statistics of stroke lesions.…”

Real-time RT PCR confirmation of selected genes: <i>F13a1</i>, <i>Nr4a1</i>, <i>Adamts5</i>, <i>Phlda2</i>. by Veronica Ulici (76661)

“…<p>Real-time PCR demonstrates that relative transcript levels for <i>F13a1</i> and <i>Phlda2</i> were decreased in LY294002 treatment after 24 hours while <i>Adamts5</i> and <i>Nr4a1</i> transcripts were increased in response to LY294002. …”

Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

“…Spermidine is required for the hypusine-dependent activation of eukaryotic translation initiation factors 5A1 (eIF5A1) and 5A2 (eIF5A2) and connects the MYC/ODC-induced deregulation of spermidine to eIF5A1/2 protein translation, which is increased during cancer cell proliferation. …”

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

BPA is a blocker of human heart sodium channels (hNav1.5). by Andrias O. O’Reilly (148537)

“…<p>A: Dose response curve of tonic block of hNav1.5 by BPA is shown as the relative decrease of sodium current response to a square voltage step to −10 mV (see inset) at various concentrations of BPA from a V_hold of −120 mV (green circles) or −90 mV (blue circles). …”

A new resource allocation model partitions the genome in five expression sectors. by Mónica Chagoyen (4253800)

“…<p><b>A)</b> Top. Resource allocation model (Model 1) based on three sectors in which the expression of their constituent genes increases (positive genes, blue), decreases (negative genes, red), or remains constant (invariant genes, brown) with increasing growth rate. …”

Images of 3D organotypic cell cultures of PC3 cells, embed in Matrigel, after segmentation and subsequent image analysis using the AMIDA software package. by Saeid Alinezhad (2795053)

“…D. In contrast, silencing of the TDRD1 gene results in significant induction of invasive properties, further loss of the structural organization or maturation of organoids, and decreased cell density.…”

The heatmap of two types high alcohol use-related Stroke showing ASMR (A), ASDR (B), Age-Standardized Rate of YLDs (C), and Age-Standardized Rate of YLLs (D) across 21 GBD regions... by Nannan Qian (10650782)

Steady state voltage, concentrations and electrochemical potentials for the nanopore in Fig 5a. by Liesbeth van Oeffelen (511929)

“…<p>The values shown are those in a plane through the axis of the nanopore, with <i>V</i>_<i>L</i>−<i>V</i>_<i>R</i> = 0.5 V and a surface charge density of −50mC/m². …”

Effects of NDGA on the expression of JA synthesis-related genes. by Hiroaki Tamaki (758505)

Increased histone acetylation, and decreased global transcription and histone H3K4 methylation in <i>Hdac1^−/+/Hdac2^−/−</i> growing oocytes. by Pengpeng Ma (389371)

Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (5) by J B Sudharsan (557453)

“…</strong> Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (<a href="http://iopscience.iop.org/0953-4075/46/15/155302/article#jpb466473eqn05" target="_blank">5</a>).…”