Ab Initio Study of the Substituent Effects on the Relative Stability of the <i>E</i> and <i>Z</i> Conformers of Phenyl Esters. Stereoelectronic Effects on the Reactivity of the Car... by Helmi Neuvonen (2643793)

“…ED/EW substituents adjust the availability of the π*_C__O antibonding orbital to interact with the lone pair orbital of the attacking nucleophile and therefore affect the reactivity:  EW substituents increase and ED substituents decrease it. Excellent correlations were observed between the rate coefficients of nucleophilic acyl substitutions and π*_C__O occupancies of the ester series <b>4 </b>and <b>5</b>.…”

siRNA knockdown of PP6R1 significantly decreases DNA-PK kinase activity. by Jun Mi (374600)

Mechanical loading decreased cortical porosity in <i>Bmpr1a</i> cKO bones. by Ayaka Iura (816567)

IL-2 accumulation decreases in response to viable <i>P. gingivalis</i> and its derived supernatant. by Hazem Khalaf (308041)

Transient fever and decreased spontaneous activity in response to rat recombinant (rr) IL-1β injection. by Masanori Yamato (534076)

Mutation of Ser-489 in GC-B to alanine but not glutamate decreases CNP-stimulated guanylyl cyclase activity. by Andrea R. Yoder (165684)

C/EBPε-deficient mice have decreased PMNs but develop equivalent hypoxemia and edema with VILI. by Heather D. Jones (476855)

HPLC METHOD IMPROVEMENT FOR 4-NONYLPHENOL DETERMINATION IN ANAEROBIC REACTORS: DECREASING SOLVENT CONSUMPTION AND WASTE GENERATION by Henrique S. Dornelles (10381255)

Table1_Exercise-Induced Atrial Remodeling in Female Amateur Marathon Runners Assessed by Three-Dimensional and Speckle Tracking Echocardiography.DOCX by Zofia Lasocka (12993621)

“…We aimed to elucidate exercise-induced changes in atrial morphology and function in female amateur marathon runners using three-dimensional (3D) echocardiography and two-dimensional (2D) speckle tracking echocardiography (STE). …”

Genome wide decrease of DNA replication eye density at the midblastula transition of <i>Xenopus laevis</i> by Marie Platel (750508)

Mitochondria-targeted antioxidants decrease intracellular and mitochondrial ROS induced by serum deprivation in RKO cells and in HDFs. by Evgeny R. Galimov (533580)

Demethylation of HPV16 LCR CpG sites decreases E6 and E7 expression. by Chunlin Zhang (663063)

“…<p>Demethylation of the CpG sites induced by 0.5 μM 5-aza-dc for 96 h decreased E6 and E7 expression, which was detected by reverse transcription PCR <b>A)</b> and quantitative real-time PCR <b>B)</b>; E6 and E7 were clearly decreased in UM-SCC47 and CaSki cells, but there was no obvious change in SiHa cells. …”

Impact of age and CMV status on repertoire clonality and richness. by Sarah A. Johnson (11355817)

Elevated IDO activity in HD mouse brains is decreased by <i>ex-vivo</i> iron chelation. by David W. Donley (3111198)

“…Iron increases levels of IDO2 in striatum (<b>E</b>) and cortex (<b>F</b>) but there was no significant effect of HD on IDO2 mRNA. …”

uPAR and cathepsin B downregulation retards nuclear translocation and decreases DNA binding activity of CREB. by Ramarao Malla (238420)

expression of primitive endoderm cell fate markers gradually increased and nanog decreased in developing embryoid bodies. by Gail Doughton (584818)

“…Statistical analysis is a one-way Anova with a Tukey’s post-hoc test, (*P = 0.1–0.5, **p = 0.001–0.01, ***p<0.001). …”

Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice by Cristina Sastre (503532)

“…</p><p>Methods</p><p>We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein E knockout (ApoE KO) mice fed with a normal chow diet (ND) or a Western-type high cholesterol-fat diet (HC) for 5 to 10 weeks, respectively.…”

Knockdown of ERRγ decreases ACEA-mediated induction of <i>FGF21</i> gene expression. by Yoon Seok Jung (1675108)

Overexpression of miR-338-3p decreases <i>in vitro</i> proliferation of GBM cells. by James R. Howe VI (4020899)

Advancing the science of NOWS research. by Sarah E. Maylott (14560785)

“…Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. …”