Image3_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.JPEG by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Supplementary Material for: Amphetamine-Type Stimulant Dependence and Association with Concurrent Use of Cocaine, Alcohol, and Cannabis: A Cross-Sectional Study by Berndt S. (11717951)

“…<b><i>Results:</i></b> The study population was on average 28.9 years old (SD = 7.7), with the majority being male (63.5%). In model 1, the adjusted odds ratio (aOR) for frequent alcohol use was 0.70 (confidence interval [CI] 0.41–1.20). …”

Table_1_Association between water source and chronic gastrointestinal diseases in Chinese: A cross-sectional and longitudinal study.DOCX by Hehua Zhang (849673)

“…The decreased risk of CGD followed a linear trend (P_fortrend < 0.01). …”

Image4_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.JPEG by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Table2_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.DOCX by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Image1_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.JPEG by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx by Zewudu Andualem (8602434)

“…Air pollution, particularly particulate matter (PM2.5 and PM10), temperature, and altitude were reported as a significant contributor. …”

Inhibition of Endothelin system during the postnatal nephrogenic period in the rat. Its relationship with hypertension and renal disease in adulthood by María Florencia Albertoni Borghese (8525688)

“…This salt sensitivity would be mediated by an increase in renomedullary expression and activity of AQP2 and α-ENaC as a consequence of increased AC6 expression and cAMP production and/or a decreased ET-1 production in the renal medulla. …”

Response assessment categories. by Mette Motzfeldt Jensen (20521593)

“…</p><p>Results</p><p>ChatGPT-4o extracted a total of 484 data points across 11 papers. The AI’s data extraction was 92.4% accurate (95% CI: 89.5% to 94.5%) and produced false data in 5.2% of cases (95% CI: 3.4% to 7.4%). …”

Aging alters ASM proliferation and extracellular matrix (ECM) deposition. by Sarah A. Wicher (11204226)

“…Aging increased deposition of collagen III (C), and fibronectin (D). Immunoblots showed aging-associated decrease in matrix modifying proteins MMP9 (E) and MMP2 (F). …”

The Formation of Social Conventions in Real-Time Environments - Fig 3 by Robert X. D. Hawkins (2579269)

Data Sheet 1_CPR knowledge among rural grassroots healthcare workers in Xinjiang, China: a cross-sectional analysis.pdf by Jin Ma (335456)

“…In the OLS model, having any prior training (+23.9; p < 0.0001), self-rated “very clear” knowledge (+13.7; p < 0.0001), and AED awareness (+5.0; p = 0.019) independently increased readiness, whereas middle-school education (−9.10; p = 0.0095) and married status (−7.77; p = 0.010) decreased readiness. …”

Data_Sheet_1_Exaggerated Exercise Blood Pressure as a Marker of Baroreflex Dysfunction in Normotensive Metabolic Syndrome Patients.PDF by Akothirene C. Dutra-Marques (10944429)

“…Introduction<p>Exaggerated blood pressure response to exercise (EEBP = SBP ≥ 190 mmHg for women and ≥210 mmHg for men) during cardiopulmonary exercise test (CPET) is a predictor of cardiovascular risk. Sympathetic hyperactivation and decreased baroreflex sensitivity (BRS) seem to be involved in the progression of metabolic syndrome (MetS) to cardiovascular disease.…”

The effect of a miR-762 antagomir on gene expression in human corneal epithelial cells and on <i>P. aeruginosa</i> invasion. by James Mun (383662)

“…<p>a Transfection of human corneal epithelial cells with an antagomir of miR-762 (antago-762) decreased the expression of miR-762 relative to a control (scrambled) antagomir, and b increased the expression of Rab5a mRNA, a predicted target of miR-762. c Antago-762 also increased the expression of RNase7 and ST-2 mRNA suggesting that miR-762 negatively regulates these innate defense genes. …”

Table_1_ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.docx by Yinshuang Wu (10057936)

“…Furthermore, ST3Gal IV overexpression enhanced the expression of several Notch pathway components such as Jagged1, Notch1, Hes1 and Hey1, while cell cycle protein expression like Cyclin D1, Cyclin E1, CDK2 and CDK4 were decreased. These results indicate that expression of ST3Gal IV is reduced in cervical cancer and plays a negative role in cell proliferation via Notch/p21/CDKs signaling pathway. …”

Cellular and molecular characterization of <i>lincRNA-uc002kmd</i>.<i>1</i>. by Xiaoli Wu (58959)

Figure S1 - Hypoxia Inducible Factor 3α Plays a Critical Role in Alveolarization and Distal Epithelial Cell Differentiation during Mouse Lung Development by Yadi Huang (381866)

“…Scale bars: 2 mm (A, B, E, F) or 200 µm (C, D, G, H).</p> <p>(TIF)</p>…”

Resistance to Erythropoiesis Stimulating Agents in Patients Treated with Online Hemodiafiltration and Ultrapure Low-Flux Hemodialysis: Results from a Randomized Controlled Trial (C... by Neelke C. van der Weerd (151348)

“…Mean transferrin saturation ratio and ferritin levels during the study tended to be lower in patients treated with HDF (−2.52% [−4.72 to −0.31]; P = 0.02 and −49 ng/mL [−103 to 4]; P = 0.06 respectively), although there was a trend for those patients to receive slightly more iron supplementation (7.1 mg/week [−0.4 to 14.5]; P = 0.06).…”

Table 1_Efficacy and safety of levetiracetam in preventing postoperative seizures in adult patients with brain tumors: a meta-analysis.docx by Yongyi Zhang (1800337)

“…The meta-analysis was conducted using RevMav 5.3 software.</p>Results<p>After the literature search and screening, nine English-language studies involving a total of 2,433 patients were analyzed. …”

Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx by Chengna Wang (21535973)

“…Meta-analysis was done with Revman 5.4. The GRADE technique assessed evidence reliability. …”