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100901
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100902
Scoparone Exerts Anti-Tumor Activity against DU145 Prostate Cancer Cells via Inhibition of STAT3 Activity
Published 2013“…Western blot and quantitative real-time PCR analyses demonstrated that scoparone suppressed the transcription of STAT3 target genes such as cyclin D<sub>1</sub>, c-Myc, survivin, Bcl-2, and Socs3. …”
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100903
Image_3_Serum pro-inflammatory biomarkers associated with improvement in quality of life in pulmonary tuberculosis.tiff
Published 2023“…</p>Methods<p>We measured serum pro-inflammatory cytokines (TNF-α and IL-8), eicosanoids (PGE2, LTB4, RvD1, Mar1, and LXA4), a marker of tissue damage (cell-free nucleosomes), and indicators of redox status (malonaldehyde, 8-isoprostane, total oxidants, and antioxidants), as well as a score of radiological abnormalities (SRA) and a QoL questionnaire, in 25 patients with pulmonary TB at the time of diagnosis (t0) and two months after the initiation of treatment (t2).…”
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100904
Table_1_Serum pro-inflammatory biomarkers associated with improvement in quality of life in pulmonary tuberculosis.xlsx
Published 2023“…</p>Methods<p>We measured serum pro-inflammatory cytokines (TNF-α and IL-8), eicosanoids (PGE2, LTB4, RvD1, Mar1, and LXA4), a marker of tissue damage (cell-free nucleosomes), and indicators of redox status (malonaldehyde, 8-isoprostane, total oxidants, and antioxidants), as well as a score of radiological abnormalities (SRA) and a QoL questionnaire, in 25 patients with pulmonary TB at the time of diagnosis (t0) and two months after the initiation of treatment (t2).…”
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100905
Experimental Investigation on the Flexural Capacity of Reinforced Concrete Beams with Treated Wastewater and Recycled Concrete Aggregates
Published 2023“…In addition, the utilization of FA at a 20% replacement ratio enhanced the flexural strength by 5% to 7%.…”
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100906
Global and local distances for several configurations of the system.
Published 2015“…(a) For global distance, we observe the smallest value when <i>p</i> = 0 and <i>r</i> ≈ 0.5, then the distance increases as <i>r</i> increases or decreases. …”
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100907
Programmed Cell Death Progresses Differentially in Epidermal and Mesophyll Cells of Lily Petals
Published 2015“…A second peak of proteinase activity was observed on day 6, and the number of mesophyll cells decreased again from days 4 to 7. …”
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100908
Block of S-phase progression at the S0 to S1 transition arrests the erythroid differentiation program.
Published 2010“…Differences between Epo+ aphidicolin and Epo control samples are significant (paired two-tailed <i>t</i> test) for GATA-2 (<i>p</i> = 0.004) and for PU.1 (<i>p</i> = 0.002). …”
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100909
<i>Rac1−/−</i> hyperproliferation in involution is linked to inflammation.
Published 2023“…Error bars: +/− SEM of <i>n =</i> 4 mice per group (P18) and <i>n</i> = 3 mice per group (Inv D2 and 4). ** <i>P</i> ≤ 0.01, * <i>P</i> ≤ 0.05. …”
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100910
3D motility of the Δ<i>phil1</i> parasites.
Published 2014“…The Δ<i>phil1</i> parasites also exhibited significantly decreased mean velocity compared to the RH parasites (<b>E</b>) and significantly reduced maximum velocity compared to both RH and Comp parasites (<b>F</b>) (paired t-test, significance indicated by asterisks). …”
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100911
Supplementary Figure S3 from TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation
Published 2023“…<p>Supplementary Figure S3 MiR-424 increases classical EMT phenotypes while decreasing TIC phenotypes. Stable miR-424 expressing MCF12A cells displaying: (A) distance migrated over 8 hours; (B) cell cycle analysis, by BrdU/PI staining; (C) adhesion to fibronectin-coated wells; and (D) ALDH1 activity quantification. …”
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100912
Table_1_Remote bednet use monitoring to describe patterns of use and exposure to female Anopheles mosquitoes in an Ugandan cohort.DOCX
Published 2022“…There was no difference between children under 5 years and adults > 30 years. LLIN use averted 50.3% of female Anopheles mosquito exposure (95% CI: 40.0–60.0%), with decreasing point estimates of efficacy across age groups: from 61.7% (95% CI: 42.6–80.7%) in children under 5 years to 48.0% (95% CI: 29.1–66.8%) in adults over 30.…”
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100913
Effects of metabolic perturbations.
Published 2022“…<p>We decreased <b>(left)</b> and increased <b>(right)</b> each reaction <i>V</i><sub>max</sub> value (<i>y</i>-axis) by a factor of two and assessed the impact on all metabolites and insulin (<i>x</i>-axis). …”
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100914
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100915
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100916
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100917
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100918
Self-renewal of AML1-ETO9a-transduced bone marrow cells is impaired in absence of <i>Inca1</i>.
Published 2014“…Two months after transplantation, <i>Inca1<sup>+/+</sup></i> cells had a clone forming frequency of 1/31, while the frequency was much lower in <i>Inca1<sup>−/−</sup></i> cells (1/164; p = 0.0001) (<b>D</b>). …”
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100919
CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin
Published 2020“…Our results show that CSC decreased the expression of both CD44 and its downstream targets CTTN and BIRC5 in MSCs, and that HA reversed these effects. …”
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100920
PowerPoint Slides for: Cognitive Impairment in Advanced Chronic Kidney Disease: The Canadian Frailty Observation and Interventions Trial
Published 2016“…Cognitive impairment was defined as a MoCA score of ≤24. We determined the prevalence and risk factors for cognitive impairment in patients with CKD stages G4-G5, not on dialysis. …”