Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents by Ayoub, Abeer J.

“…Their IC50 values ranged from 1.2 to 9.04 µM for interleukin-6; from 1.5 to 19.3 µM for Chemokine (C-C) Ligand 2; from 2.4 to 5.2 µM for nitric oxide; and from 1.1 to 20.5 µM for prostaglandin E2. …”
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Image1_Lonicerin attenuates house dust mite-induced eosinophilic asthma through targeting Src/EGFR signaling.jpg by Zhenan Deng (14297111)

“…Finally, in vivo experiments confirmed that lonicerin inhibited activation of the Src/EGFR pathway by decreasing their phosphorylation. Taken together, the present study demonstrated that lonicerin could suppress HDM-induced eosinophilic asthma in mice through inhibiting the activation of Src/EGFR pathway, which also provides a basis for further research as a new potentially therapeutic agent for eosinophilic asthma and its underlying mechanisms in the future.…”

Table_6_Enteric nervous system damage caused by abnormal intestinal butyrate metabolism may lead to functional constipation.xlsx by Le Wang (165105)

“…<p>Functional constipation (FC) is a high morbidity gastrointestinal disease for which dysfunction in the enteric nervous system is a major pathogenesis mechanism. …”

Data_Sheet_1_Enteric nervous system damage caused by abnormal intestinal butyrate metabolism may lead to functional constipation.docx by Le Wang (165105)

“…<p>Functional constipation (FC) is a high morbidity gastrointestinal disease for which dysfunction in the enteric nervous system is a major pathogenesis mechanism. …”

Table_8_Enteric nervous system damage caused by abnormal intestinal butyrate metabolism may lead to functional constipation.xlsx by Le Wang (165105)

“…<p>Functional constipation (FC) is a high morbidity gastrointestinal disease for which dysfunction in the enteric nervous system is a major pathogenesis mechanism. …”

Table1_Lonicerin attenuates house dust mite-induced eosinophilic asthma through targeting Src/EGFR signaling.xlsx by Zhenan Deng (14297111)

“…Finally, in vivo experiments confirmed that lonicerin inhibited activation of the Src/EGFR pathway by decreasing their phosphorylation. Taken together, the present study demonstrated that lonicerin could suppress HDM-induced eosinophilic asthma in mice through inhibiting the activation of Src/EGFR pathway, which also provides a basis for further research as a new potentially therapeutic agent for eosinophilic asthma and its underlying mechanisms in the future.…”

Exercise During the First Trimester of Pregnancy and the Risks of Abnormal Screening and Gestational Diabetes Mellitus by Samantha F. Ehrlich (3873010)

“…Exercise meeting or exceeding the 75^th percentile decreased the risks of abnormal screening and GDM, by 4.8 (95% CI 1.1, 8.5) and 2.1 (0.2, 4.1) fewer cases per 100, respectively, in adjusted analyses. …”

Table2_Lonicerin attenuates house dust mite-induced eosinophilic asthma through targeting Src/EGFR signaling.xlsx by Zhenan Deng (14297111)

“…Finally, in vivo experiments confirmed that lonicerin inhibited activation of the Src/EGFR pathway by decreasing their phosphorylation. Taken together, the present study demonstrated that lonicerin could suppress HDM-induced eosinophilic asthma in mice through inhibiting the activation of Src/EGFR pathway, which also provides a basis for further research as a new potentially therapeutic agent for eosinophilic asthma and its underlying mechanisms in the future.…”

Triassic record of Paleo-Tethyan subduction: Evidence from prograde metamorphic P–T paths of the Baqing eclogite, eastern Qiangtang, central Tibet by Xin Wei (119082)

“…We calculated the peak metamorphic conditions of the Baqing eclogite using the Garnet–Omphacite–Phengite–Quartz thermobarometers to be 26.5 ± 1 kbar and 730 ± 60°C, consistent with the results (23.5–27.5 kbar, 730–750°C) calculated using a P–T pseudosection. …”

Circulating MicroRNAs as Easy-to-Measure Aging Biomarkers in Older Breast Cancer Patients: Correlation with Chronological Age but Not with Fitness/Frailty Status by Sigrid Hatse (12560)

“…Plasma levels of miR-20a-3p, miR-30b-5p, miR106b, miR191 and miR-301a were confirmed to show significant age-related decreases (all p≤0.004). …”

Impact of case/control ratio misspecification on sample size inference. by Hanna Julienne (469265)

“…For each replicate we randomly sampled 5,000 cases and 20,000 controls and tested for association between <b><i>G</i></b> and <b><i>Y</i></b> using these samples and after sub-sampling cases (i.e. using a sub-sample of the 5,000 cases and the 20,000 controls, top panel) or controls (i.e. using the 5,000 cases and a sub-sample of the 20,000 controls, bottom panel), in order to mimic situation where either cases or controls would be missing for some SNPs. …”

Table_3_Enteric nervous system damage caused by abnormal intestinal butyrate metabolism may lead to functional constipation.xlsx by Le Wang (165105)

“…<p>Functional constipation (FC) is a high morbidity gastrointestinal disease for which dysfunction in the enteric nervous system is a major pathogenesis mechanism. …”

Does wearing swimming goggles affect corneal morphology in keratoconic eyes? by Döndü Melek Ulusoy (5762939)

“…<div><p>ABSTRACT Purpose: A significant transient increase in intraocular pressure in individuals wearing swimming goggles has been demonstrated in previous studies. …”

Data_Sheet_1_The Influence of Moderate Physical Activity on Brain Monoaminergic Responses to Binge-Patterned Alcohol Ingestion in Female Mice.PDF by Trevor J. Buhr (10191398)

“…However, access to alcohol during DID eliminated wheel running-related decreases of norepinephrine, serotonin, and 5-HIAA content in the hypothalamus, but also to a lesser extent for norepinephrine in the hippocampus and caudal cortical areas. …”

Table3_Lonicerin attenuates house dust mite-induced eosinophilic asthma through targeting Src/EGFR signaling.xlsx by Zhenan Deng (14297111)

“…Finally, in vivo experiments confirmed that lonicerin inhibited activation of the Src/EGFR pathway by decreasing their phosphorylation. Taken together, the present study demonstrated that lonicerin could suppress HDM-induced eosinophilic asthma in mice through inhibiting the activation of Src/EGFR pathway, which also provides a basis for further research as a new potentially therapeutic agent for eosinophilic asthma and its underlying mechanisms in the future.…”

Table1_Growth and anemia among children with tuberculosis infection at different sites in Southwest China.docx by Zhongmin Gao (16362771)

“…Children aged 0.5–2 years exhibited the highest anemia prevalence of 70.6% (48/68) among the four age groups.The TPA group had the highest incidence of anemia (70.5%, 67/95) compared to T group and TP group.Compared with the treatment group, the abandonment group had a lower BAZ, HAZ and levels of HB and ALB, a higher rate of severe malnutrition, and higher nutritional risk scores. …”

Data_Sheet_2_Exosomes Derived From Macrophages Enhance Aerobic Glycolysis and Chemoresistance in Lung Cancer by Stabilizing c-Myc via the Inhibition of NEDD4L.DOCX by Huan Wang (109286)

“…MDE exhibited high expression level of several miRNA including miR-3679-5p. Mechanistically, miR-3679-5p was delivered to lung cancer cells by MDE, downregulating the expression of a known E3 ligase, NEDD4L, which has been identified as a key regulator controlling the stability of c-Myc. …”

Data_Sheet_1_Physiological and transcriptional responses of seed germination to moderate drought in Apocynum venetum.docx by Zhibo Wu (3826858)

“…Here, the physiological and transcriptional changes during seed germination of A. venetum under different PEG-6000 treatments (5 to 20%) were examined. …”

Data_Sheet_1_Autophagy Controls Nrf2-Mediated Dichotomy in Pressure Overloaded Hearts.pdf by Weiwei Wu (244139)

“…<p>Burgeoning evidence has indicated that normal autophagy is required for nuclear factor erythroid 2-related factor (Nrf2)-mediated cardiac protection whereas autophagy inhibition turns on Nrf2-mediated myocardial damage and dysfunction in a setting of pressure overload (PO). However, such a concept remains to be fully established by a careful genetic interrogation in vivo. …”

Table_2_Enteric nervous system damage caused by abnormal intestinal butyrate metabolism may lead to functional constipation.xlsx by Le Wang (165105)

“…<p>Functional constipation (FC) is a high morbidity gastrointestinal disease for which dysfunction in the enteric nervous system is a major pathogenesis mechanism. …”