RpoS-regulated <i>SEN1538</i> gene promotes resistance to stress and influences <i>Salmonella enterica</i> serovar enteritidis virulence by Aryashree Arunima (8518125)

“…Here, we identified <i>SEN1538</i> as a conserved RpoS-regulated gene belonging to the KGG protein superfamily. …”

Signal pathway enrichment analysis. by Signe E. Cremer (7861373)

“…Proteins are ranked within a pathway from high to low frequency, and the pathways* are ranked according to the significance-level of enrichment (decreasing enrichment-level left to right). …”

Patterns of Gene Expression in Peripheral Blood Mononuclear Cells and Outcomes from Patients with Sepsis Secondary to Community Acquired Pneumonia by Patricia Severino (5658397)

“…Microarray-based expression profiling is a powerful approach for the investigation of complex clinical conditions such as sepsis. …”

Data_Sheet_1_Association of Early and Supernormal Vascular Aging categories with cardiovascular disease in the Chinese population.pdf by Qiuyu Cao (12559153)

“…We aimed to investigate the association between vascular aging categories and cardiovascular events in a Chinese cohort.</p>Methods<p>We explored the association of vascular aging categories with incident cardiovascular disease in a community cohort in Shanghai, China, which included 10,375 participants following up for 4.5 years. …”

Video4_Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation.MP4 by Serena Van (11276529)

“…A single rapid infusion of DOX (10 mg/kg i.v.) reduced positive volumetric lymph flow to 29.7 ± 10.8% (n = 7) of baseline in mesenteric LVs in vivo. …”

Survey of polychlorinated dibenzo-<i>p</i>-dioxins, polychlorinated dibenzofurans and non-<i>ortho</i>-polychlorinated biphenyls in US meat and poultry, 2012–13: toxic equivalency... by Sara J. Lupton (1439035)

“…<p>The US Department of Agriculture (USDA) conducts a statistically based survey of the domestic meat supply (beef, pork, chicken and turkey) to determine current levels of polychlorinated dibenzo-<i>p</i>-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and non-<i>ortho</i>-polychlorinated biphenyls (<i>no</i>-PCBs) every 5 years. …”

KLF4 is required for suppression of histamine synthesis by polyamines during bone marrow-derived mast cell differentiation by Kazuhiro Nishimura (713297)

“…We found that the efficiency of KLF4 synthesis in response to DFMO treatment was enhanced by the existence of a GC-rich 5′-untranslated region (5′-UTR) on <i>Klf4</i> mRNA, regardless of the recognition of the initiation codon. …”

Image2_Ethyl 2-Succinate-Anthraquinone Attenuates Inflammatory Response and Oxidative Stress via Regulating NLRP3 Signaling Pathway.TIF by Burong Feng (11661529)

“…In vivo, we revealed that the LHD, in different doses (6.25 mg/kg, 12.5 mg/kg, 25 mg/kg, 50 mg/kg), has a protective effect on stress physiological responses by assessing the body temperature of mice. …”

Autophagy Is Involved in the Cardioprotection Effect of Remote Limb Ischemic Postconditioning on Myocardial Ischemia/Reperfusion Injury in Normal Mice, but Not Diabetic Mice by Zhihua Han (28856)

“…</p><p>Methodology and Results</p><p>Streptozocin (STZ) induced DM mice model and myocardial IR model were established. Using a noninvasive technique, RIPostC was induced in normal mice (ND) and DM mice by three cycles of ischemia (5 min) and reperfusion (5 min) in the left hindlimb. …”

Video2_Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation.MP4 by Serena Van (11276529)

“…A single rapid infusion of DOX (10 mg/kg i.v.) reduced positive volumetric lymph flow to 29.7 ± 10.8% (n = 7) of baseline in mesenteric LVs in vivo. …”

Effectiveness of XP-Endo Finisher in the reduction of bacterial load in oval-shaped root canals by Maria Cristina Carvalho (6745535)

“…ANOVA, Tukey's test, and Bonferroni post-hoc test were used at a 5% significance level. Culturable bacteria were present in all S1 samples (p>0.05). …”

Comparative pharmacokinetic analysis of levonorgestrel-releasing intrauterine systems and levonorgestrel-containing contraceptives with oral or subdermal administration route by Birte Maria Hofmann (9454366)

“…<p> To compare systemic exposure to levonorgestrel (LNG) released from commercially available intrauterine systems (IUSs), a subdermal implant, and oral contraceptives.</p> <p> An integrated population pharmacokinetic (popPK) analysis of data from over 3400 individuals in ten clinical studies with six different LNG-releasing contraceptives (four long-acting reversible contraceptives [LARCs: LNG-IUS 8, 12, and 20, initially releasing LNG 14, 17.5, and 20 μg/day, a subdermal implant initially releasing LNG 100 μg/day according to label]; progestin-only pill [POP: LNG 30 μg/day]; and combined oral contraceptive [COC] pill [LNG 100 μg/day and ethinylestradiol 20 μg/day]), was conducted to generate a popPK model. …”

Data_Sheet_1_Prophylactic feeding of neomycin to Holstein calves alters gut microbiota, bile acid metabolism, and expression of genes involved in immunometabolic regulation.docx by Lautaro R. Cangiano (16910664)

“…The expression of FXR and TGR5 in the liver was increased in the ST group compared with CTL, and in adipose tissue, 5 genes related to triglyceride, gluconeogenesis, and immune activation were differentially expressed between CTL and ST. …”

Image2_The Preventive Role of Hydrogen-Rich Water in Thioacetamide-Induced Cholangiofibrosis in Rat Assessed by Automated Histological Classification.TIF by Chaofu Li (9733762)

“…RNA-seq analysis revealed that H₂ results in a decline in glycolysis. Moreover, in the third experiment, the incidence of microscopic or suspicious tumors and the ratio of liver lesions was decreased after long-term use of H₂ (12.5%, 0.57% ± 0.45) compared with untreated group (100%, 0.98% ± 0.73). …”

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin by Rance Nault (3847747)

“…Phosphatidylserines, phosphatidylethanolamines, phosphatidic acids, and cardiolipins decreased 4.1-, 5.0-, 5.4- and 7.4-fold, respectively, while ceramides increased 6.6-fold. …”

CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis by Baoping Deng (9081380)

“…To evaluate the biological functions of circFNDC3B, assays were employed including 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT), flow cytometry, and Caspase-3 activity assays. …”

Moist-Retaining, Self-Recoverable, Bioadhesive, and Transparent in Situ Forming Hydrogels To Accelerate Wound Healing by Jun Li (6494)

“…The physicochemical properties of M-CMCS/O-HES hydrogels with various ratios were investigated, and M-CMCS/O-HES hydrogel with a volume ratio of 5:5 exhibited appropriate gelation time, notable water-retaining capacity, self-recoverable conformal deformation, suitable biodegradability, and good biocompatibility for wound-healing application. …”

Table 1_Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels of Clausena lansium L. Skeels.docx by Zhichang Zhao (8545662)

“…</p>Results<p>The PP (purple peel) has higher levels of a-carotene and b-carotene but lower levels of chlorophyll a, chlorophyll b, and lutein compared to BP. …”

Video1_Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation.MP4 by Serena Van (11276529)

“…A single rapid infusion of DOX (10 mg/kg i.v.) reduced positive volumetric lymph flow to 29.7 ± 10.8% (n = 7) of baseline in mesenteric LVs in vivo. …”

Supplemental data and data sets for: Extracellular Na+ and Orai1 contribute to endothelial wound healing (Xu et al) by Ningyong Xu (6330494)

“…We found that PAEC monolayers migrated into wound areas and achieved confluence within 24 hours post-scratch. There was a fast healing phase within 5 hours, followed by a slow-healing phase between 5 and 24 hours. …”