Various stereological parameters characterizing lung parenchyma and AEII before, during and after alveolarization as well as in adults. by Julia Hüttmann (22656283)

“…PLoS One. 2024 Mar 14;19(3):e029. b) The total number of alveolar epithelial cells type II (N(AEII, lung)) shows a significant increase after the end of bulk alveolarization and in adults compared to 3 days old rats. c) During alveolarization the number of AEII per mm² alveolar surface (N(AEII, lung)/S(alveoli, lung)) decreases continuously reaching the significant lowest values in adults. d) The number of AEII related to lung volume decreases continuously during alveolarization. …”

Suppression of DNA methyltransferases is sufficient to induce demethylation. by Guolin Chai (49048)

“…(D) A schematic diagram showing the <i>p21^Waf1/Cip1</i> promoter, with the black region indicating the fragment which underwent bisulfite sequencing (−233 to +2 relative to transcription start site). …”

DeepTrajectory method overview. by Erik Pfeiffenberger (5714645)

“…(C) These temporal features are used to perform supervised mini-batch training (<i>b</i>₁, ⋯, <i>b</i>_<i>k</i>) to train an RNN with several layers of GRUs that is able to classify each snapshot of the trajectory into three classes: improved state (<i>I</i>), no-change state (<i>N</i>), decreased state (<i>D</i>). Predictions for the trajectory of a new protein system, for which this state change assignment is unknown, are assigned by applying the trained DeepTrajectory model to every snapshot. …”

A transgenic synthetic 21U RNA shows characteristics of endogenous 21U RNAs. by Allison C. Billi (170245)

“…(C–E) 21UR-synth is a <i>prg-1</i>-dependent, germline-enriched 21U RNA. 21UR-synth detection by Taqman RT-qPCR (C) and northern blot (D,E) is greatly decreased in <i>prg-1(tm872)</i> and <i>glp-4(bn2)</i> germline-deficient mutant animals, but intact in <i>rde-4(ne301)</i> mutant animals. …”

Low oxygen induces TSP-1 expression by different mechanisms. by Chen Zhao (225070)

“…The ratio of repressed TSP-1 mRNA over free mRNA decreases more than tenfold in the condition of 2% oxygen. …”

Administration of soluble Robo4 (sR4) shifts the Robo4 knockout to the WT phenotype. by Fernanda Gimenez (840629)

“…(B) SK lesions and angiogenesis severity was decreased in R4 KO mice treated with sR4. (C) Representative eye photos show that R4 KO mice treated with sR4 do not develop the severe phenotype that R4 KO control animals do (D) Hematoxylin and eosin staining was carried out on 6-μm sections, and pictures were taken 40 x magnification. …”

miR-720 promotes odontogenic differentiation of DPCs. by Emilio Satoshi Hara (393519)

“…. * P<0.05, *** P<0.001, unpaired <i>t</i>-test, compared to si-control group. C–D) Knockdown of miR-720 decreased the differentiation of DPCs. …”

Fear conditioning-induced changes in proBDNF and Arc/Arg3.1 protein in the CA1 of hippocampus. by Philip Barnes (270610)

“…(c) Arc/Arg3.1 protein in CA1 was selectively decreased in rats receiving BDNF ASO, but not PBS or BDNF MSO (MSO) infusions prior to conditioning. n = 4 (d) A separate group of rats (n = 11) were fear conditioned to two contexts (A and B), they received intrahippocampal infusions of tPA-STOP 90 m in before conditioning in one of the contexts and vehicle prior to training in the other. …”

Figure S1 - Aleuria Aurantia Lectin (AAL)-Reactive Immunoglobulin G Rapidly Appears in Sera of Animals following Antigen Exposure by Songming Chen (135195)

MiR-34a and miR-34c overexpression or PDGFR-α/β silencing increases the response of NSCLC cells to TRAIL-induced apoptosis. by Michela Garofalo (276614)

“…MiR-34a or miR-34c and not miR-34b forced expression decreases PDGFRβ expression levels and reduces the activation of the ERK1/2. …”

Time course of adiponectin level in the explants incubation medium and serum. by Hongying Ye (130762)

“…<p>At the age of 5w, 6w and 7w, adiponectin level in the explants incubation medium (EIM) of the db/db mice was significantly lower than that of lean mice(P<0.01) (Fig. 8A), indicating that adiponectin production from the epididymal adipose tissue was decreased in db/db mice; Adiponectin in the serum was comparable between db/db mice and lean mice at each point (Fig. 8B).…”

Effect of the MRP on the accumulated number of infected nodes. by Damian Tago (2833622)

“…<p>When the disease can be transmitted only through the trade network (green line), the MRP is a very efficient tool to stop the spreading of the disease. …”

FIGURE 3 from Multi-institutional Prognostic Modeling in Head and Neck Cancer: Evaluating Impact and Generalizability of Deep Learning and Radiomics by Michal Kazmierski (16044758)

“…Spearman rank correlation of the predictions of each model with tumor volume against performance in terms of AUROC (<b>A</b>) and <i>C</i>-index (<b>B</b>), respectively. …”

DataSheet13_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.ZIP by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

DataSheet10_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.ZIP by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Presentation1_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.PPTX by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image7_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

DataSheet7_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.ZIP by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Presentation3_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.PPTX by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”

Image14_Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways.TIF by Mi Zhou (9884)

“…</p><p>Results: Valsartan rescued LPS-reduced cell viability of BEAS-2B cells, improved the pulmonary function, ameliorated pathological lung injury in mice with ALI, ameliorated LPS-induced neutrophil recruitment in BALF and lung tissue of mice, attenuated oxidative stress by increasing the level of SOD and decreasing that of MDA and GSSG, inhibited LPS-induced MUC5AC overproduction, decreased the LPS-induced increase in expression of pro-inflammatory cytokines/chemokines including TNF-α, IL-6, IL-1β, CXCL-1 and CXCL-2, and restored the expression of anti-inflammatory IL-10. …”