Image1_Hyperglycemia exerts disruptive effects on the secretion of TGF-β1 and its matrix ligands, decorin and biglycan, by mesenchymal sub-populations and macrophages during bone r... by Norhayati Yusop (16443786)

“…Short-term glucose exposure increased TGF-β₁ and decorin secretion by committed osteoblasts but had a lesser effect on transit-amplifying cells. In contrast, the long-term exposure of CB-MSCs to high glucose was associated with decreased TGF-β₁ and increased decorin secretion. …”

Data_Sheet_1_In-hospital major bleeding in patients with acute coronary syndrome medically treated with dual anti-platelet therapy: Associated factors and impact on mortality.docx by Yihong Sun (442494)

“…Multivariable analysis showed advancing age (RR = 1.52 for every 10 years increase, 95% CI: 1.13, 2.05), impaired renal function (RR = 1.79, 95% CI: 1.10, 2.92), use of fibrinolytic drugs (RR = 2.93, 95% CI: 1.55, 5.56), and severe diseases other than cardiovascular and renal diseases (RR = 5.56, 95% CI: 1.10, 28.07) were associated with increased risk of major bleeding, whereas using renin–angiotensin system inhibitors (RR = 0.54, 95% CI: 0.36, 0.81) was associated with decreased risk of major bleeding. …”

Image_1_Stimulatory Effect of Tofacitinib on Bone Marrow Adipocytes Differentiation.jpeg by Jean-Guillaume Letarouilly (10035939)

“…</p>Results<p>In non-inflammatory conditions, the gene expression of Runx2 and Dlx5 decreased in Ob treated with Tofa (p <0.05). …”

Data_Sheet_1_Revisiting the complex time-varying effect of non-pharmaceutical interventions on COVID-19 transmission in the United States.docx by Gonghua Wu (14821738)

“…</p>Results<p>We found that (i) the empirical reduction in reproduction number attributable to integrated NPIs was 52.0% (95%CI: 44.4, 58.5%) by August and September 2020, whereas the reduction continuously decreased due to the relaxation of NPIs in following months; (ii) international travel restrictions, stay-at-home requirements, and restrictions on gathering size were important NPIs with the relative contribution higher than 12.5%; (iii) vaccination alone could not mitigate transmission when the fully vaccination coverage was less than 60%, but it could effectively synergize with NPIs; (iv) even with fully vaccination coverage >60%, combined use of NPIs and vaccination failed to reduce the reproduction number below 1 in many states by February 2022 because of elimination of above NPIs, following with a resurgence of COVID-19 after March 2022.…”

Demographic data of the study cohort. by Chuan-Hsun Chang (20348083)

“…</p><p>Results</p><p>The average age was 65.1 years, with a median follow-up time of 5.7 years and a median duration of endocrine therapy of 4.5 years. …”

Loss of <i>AmyD</i> reduces larval size in the <i>AKHRi</i> model. by Audrey Nicol (19500765)

“…Metabolites were measured from a heat-treated lysate consisting of 5 larvae per sample and quantified for N = 5–10 samples per group. …”

<i>B</i>. <i>burgdorferi</i>–induced metabolic changes in memory macrophages. by Diego Barriales (4890067)

“…The data underlying the graphs in Fig 5 can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001062#pbio.3001062.s013" target="_blank">S5 Data</a> and GSE125503. …”

Data_Sheet_1_Mixed silage with Chinese cabbage waste enhances antioxidant ability by increasing ascorbate and aldarate metabolism through rumen Prevotellaceae UCG-004 in Hu sheep.d... by Chuang Li (2010226)

“…<p>Silage is rich in nutrients, which can make up for the lack of seasonal roughage, and has a certain promotion effect on the intensive feeding of ruminants. …”

Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders by Eva C. Schulte (213836)

“…RLS: p = 0.0001 to 5.80x10^-9) and general population controls (PD vs. …”

Histogram of mass spectra from the CH and CR groups. by Chang Tian (636710)

“…<p>Histogram of mass spectra from the CH (A) and CR (B) groups before and after treatment showed increased expression of peptides at 1489.3, 1079.1, 3358.6, and 1589.2 Da and decreased expression of those at 3037.1, 2620.6, 3162.0, 2483.2, 3290.4, 2877.7, 2258.6, 2346.2, 2021.6, 1721.7, and 2184.9 Da in the CH group, and increased expression of peptides at 1774.3 Da and decreased expression of those at 3192.5, 1721.3, and 2591.4 Da in the CR group (p < 0.05).…”

Estimating germline maintenance. by Mareike Koppik (4489318)

“…Data represent Bayesian posterior means and 95% credible intervals from Baur and Berger (2020) [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002049#pbio.3002049.ref007" target="_blank">7</a>]. …”

Effects of <i>C</i>. <i>obtusa</i> essential oil on survival of dendritic cells (DCs) and peripheral blood mononuclear cells (PBMCs). by Seung-Heon Shin (5566055)

“…<p>DC survival decreased significantly with 0.1% of the essential oil (A), and PBMC survival decreased significantly at concentration exceeding 0.5% (B). …”

tPA and PAI-1 level in MCAo mouse IBZ astrocytes respond to MSC. by Hongqi Xin (367360)

“…<p>(5a) presents the individual IBZ astrocytes dissected using LCM (before and after dissection), and tPA and PAI-1 mRNA level in these astrocytes with or without MSC treatment are shown in (b). …”

Evolutionary changes in bacterial maximum population size and resistance against ancestral PPV-phage. by Ville-Petri Friman (140973)

“…The data is pooled over temperature treatments and the error bars denote ± s.e.m. (N = 5).</p>…”

Epidemic and Non-Epidemic Hot Spots of Malaria Transmission Occur in Indigenous <i>Comarcas</i> of Panama by William Lainhart (2793463)

“…<div><p>From 2002–2005, Panama experienced a malaria epidemic that has been associated with El Niño Southern Oscillation weather patterns, decreased funding for malaria control, and landscape modification. …”

Stability of encapsulated and non-encapsulated anthocyanin in yogurt produced with natural dye obtained from Solanum melongena L. Bark by Flavia Jamille de Figueiredo Paes Barretto (10379300)

“…<div><p>Abstract This research evaluated the stability of non-encapsulated and spray-dried encapsulated anthocyanin from Solanum melongena L. bark as a natural dye in yogurts. Anthocyanin was extracted using 70% cereal alcohol acidified with citric acid at pH 2.0. …”

Preliminary estimates of changes in the occurrence of shifting cultivation between today and 2030, 2060 and 2090. by Andreas Heinimann (761681)

“…<p>This visualization is based on the estimation of landscapes showing signs of shifting cultivation around 2010 (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0184479#pone.0184479.g005" target="_blank">Fig 5</a>) as base year and estimated decreases of shifting cultivation (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0184479#pone.0184479.t003" target="_blank">Table 3</a>) based on the expert surveys and observed trend between the Butler map and our 2010. …”

The Genome of the Toluene-Degrading <i>Pseudomonas veronii</i> Strain 1YdBTEX2 and Its Differential Gene Expression in Contaminated Sand - Fig 6 by Marian Morales (3331785)

“…Line width linearly decreasing between 100 and 1 for ²log CPKM between 50 and 5. …”

TRPA1-mediated insulin release is independent of voltage-gated Na⁺, Ca²⁺ and K_ATP channels. by De-Shou Cao (160865)

“…</b> In the presence of Ca²⁺ channel blocker nimodipine (5 µM) basal insulin release is decreased significantly (n=6, * p<0.05), but there is a significant increase when challenged with AITC+nimodipine (n=6,** p<0.01). …”

datasheet1_Spatio-Temporal Variability of Peat CH4 and N2O Fluxes and Their Contribution to Peat GHG Budgets in Indonesian Forests and Oil Palm Plantations.docx by Erin Swails (10323518)

“…The GHG budget was also ten times higher in the secondary forest (10.2 ± 4.5) than in the primary forests (0.9 ± 3.9) on the account of a larger peat C budget and N₂O emission rate. …”