Identification and characterization of a robust suppressor that ameliorates the locomotion defects in the <i>C</i>. <i>elegans</i> model of SOD1-associated ALS. by Goran Periz (645823)

“…The western blot lanes are from the same gel and exposure. (<b>D</b>) Sequence analysis of the M1 strain, revealing that independent mutations in two genes, a lysine-specific demethylase, <i>spr-5 (R646Q)</i>, and a ubiquitin ligase, <i>ufd-2 (W824X)</i>, are required for the full suppressor phenotype. …”

Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021 by GBD 2021 Europe Life Expectancy Collaborators (21408850)

Functional validation of highly-expressed gametophyte genes by quantification of transmission rates in <i>Ds-GFP</i> insertional mutants. by Cedar Warman (8654994)

“…In this class, an increase in log2(FPKM) was significantly associated with a decrease in marker transmission (linear regression, p = 0.0120).…”

Image 1_A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors.pdf by Huiyi Hu (11226995)

“…Moreover, survival analysis revealed the prognostic significance of this four-gene signature: high TOP2A with low ABLIM1, FHL5, and MAP3K8 expression correlated with decreased overall survival in ULMS, implicating their potential role as diagnostic and prognostic markers. …”

Removal of <i>Bmp2, Bmp4, and Bmp7</i> from the AER resulted in an initial broadening and then loss of <i>Fgf8</i> expression in the AER but normal <i>Fgf10</i> expression. by Kyung-Suk Choi (162073)

“…In E11.5 limb buds, <i>Fgf8</i> expression was severely decreased in the central and anterior AER in embryos that contained only a single allele of <i>Bmp7</i> (E and K; <i>Bmp7^f/+</i>; <i>Bmp2^f/f, Bmp4^f/f, Msx2-cre</i>) or no functional <i>Bmp</i> alleles (F and L; <i>Bmp7^f/f</i>; <i>Bmp2^f/f, Bmp4^f/f, Msx2-cre)</i>. …”

Supplementary Material for: Diagnosis Accuracy of Transcutaneous Bilirubinometry in Very Preterm Newborns by Rubio A. (2916437)

“…<div><div><div><div><strong><em>Background:</em></strong> Transcutaneous bilirubin (TcB) is a validated test for systematic screening of neonatal hyperbilirubinemia and monitoring term and near-term infants under phototherapy. …”

Table1_Is the duration of dual antiplatelet therapy (DAPT) excessive in post-angioplasty in chronic coronary syndrome? Data from the France-PCI registry (2014–2019).docx by A. Mezier (14835628)

“…</p>Results<p>Post-percutaneous coronary intervention (PCI) DAPT duration was > 12 months for 53.1% of patients treated for CCS; 30.5% had a DAPT between 7 and 12 months, and 16.4% a DAPT ≤ 6 months. …”

Supplementary Material for: Effects of Sex and Physical Activity Level on Serum Biomarker-Based Physiological Dysregulation: The Impact to Predict Frailty and Mortality in the Queb... by Ghachem A. (10489754)

“…<b><i>Conclusion:</i></b> Our results showed that both sex and PAL have a significant effect on physiological dysregulation levels and rates of change. …”

<b>Data from: </b><b>Experimentally increased food availability allows for earlier departure in a long-distance migratory shorebird</b> by Thomas Lameris (20888213)

“…We only included detections that showed a typical pattern of a ‘departure event’, with a peak in signal strength followed by a gradual decrease in signal strength (Müller <i>et al.…”

Low iodine diet does not improve the efficacy of radioiodine for the treatment of Graves’ disease by Vanessa A. Santarosa (6140990)

“…Results The LID group experienced a 23% decrease in urinary iodine after 1 week on the diet and a significant 42% decrease after 2 weeks on the diet. …”

Supplementary Material for: Magnetic Resonance Spectroscopy following Mild Traumatic Brain Injury: A Systematic Review and Meta-Analysis on the Potential to Detect Posttraumatic Ne... by Eisele A. (9071537)

“…Group analyses were performed per metabolite using a random-effects model. <b><i>Results:</i></b> Four and 2 out of 5,417 articles met the inclusion criteria for the meta-analysis and systematic review, respectively. …”

Expression of ‘muscle’ genes in the tendon during early postnatal development. by Heather L. Dingwall (14573796)

“…<p>A) Heatmap showing RNA expression of muscle-associated genes in Clusters 1, 2, and 5 with specific genes indicated. …”

Changes in Microbial Communities, Including both Uncultured and Culturable Bacteria, with Mid-Ocean Ballast-Water Exchange during a Voyage from Japan to Australia by Akiko Tomaru (511024)

“…Uncultured (i.e., total) and culturable bacteria were counted and were characterized by using denaturing gradient gel electrophoresis (DGGE). There was a clear decrease over time in numbers of uncultured microorganisms, except for heterotrophic nanoflagellates, whereas the abundance of culturable bacteria initially decreased after the ballast-water exchange but then increased. …”

Table_1_Impact of the COVID-19 Pandemic on Mental Well-Being. A Nationwide Online Survey Covering Three Pandemic Waves in Poland.pdf by Mateusz Babicki (9136071)

“…There was no significant effect on the subjective quality-of-life assessment. Moreover, there was a gradual decrease in anxiety about being infected with COVID-19 as well as reduced adherence to the Minister of Health's recommendations. …”

Model for a role of monomeric and fibrillar β₂-microglobulin (β₂m) cytotoxicity in dialysis related amyloidosis. by Morwenna Y. Porter (197770)

“…<p>(1) Elevated levels of circulating β₂m monomer form amyloid deposits in osteoarticular tissues. (2) Circulating monocytes are able to differentiate into both macrophages and osteoclasts. (3) Monocyte-derived macrophages infiltrate β₂m amyloid deposits, but the resistance of the amyloid fold to proteolysis in combination with β₂m amyloid cytotoxicity, prevents the clearance of the amyloid deposits. (4) β₂m amyloid induced monocyte/macrophage cell death also contributes to reduced osteoclast formation, causing a decrease in the resorption of old bone. (5) Osteoblast cell death in the presence of β₂m monomer and/or fibrils causes decreased bone formation. (6) Decreased bone resorption and formation contribute to pathological alterations to normal bone homeostasis. (7) Chondrocyte cell death in the presence of β₂m monomer and/or fibrils causes decreased cartilage formation, which could allow gradual loss of this tissue and exposure of bone to cytotoxic β₂m monomer and fibrils.…”

Supplementary Material for: IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia by Schauer A.E. (4098916)

Supplementary Material for: The Effect of Improved Dysphagia Care on Outcome in Patients with Acute Stroke: Trends from 8-Year Data of a Large Stroke Register by Suntrup-Krueger S. (3917630)

“…Pneumonia incidence was higher in dysphagic stroke cases (adjusted OR 5.4 [5.2–5.5], <i>p</i> < 0.001), accompanied by a worse mRS at discharge (adjusted OR for mRS ≥3: 3.1 [3.0–3.1], <i>p</i> < 0.001) and higher mortality (adjusted OR 3.1 [3.0–3.2], <i>p</i> < 0.001). …”

Table1_Risk factors and early markers for echovirus type 11 associated haemorrhage-hepatitis syndrome in neonates, a retrospective cohort study.docx by Ping Wang (42415)

“…Progressive decrease in haemoglobin levels (per 10 g/L; OR, 1.5; 95% CI, 1.1–2.0) and platelet (PLT) < 140 × 10⁹/L at early stage of illness (OR, 17.7; 95% CI, 1.4–221.5) were associated with the development of haemorrhage-hepatitis syndrome. …”

FIGURE 7 from Signaling Pathway Alterations Driven by BRCA1 and BRCA2 Germline Mutations are Sufficient to Initiate Breast Tumorigenesis by the PIK3CA^H1047R Oncogene by Poornima Bhat-Nakshatri (15293182)

“…<b>D,</b> Immortalized BRCA1 or BRCA2 mutant cells but not cells from non-carriers are sensitive to DMAPT. …”

Supplementary Material for: Comparing efficacies of different exercises on androgen deprivation therapy adverse effects in prostate cancer patients: a network meta-analysis by Hu S. (5689703)