Structure–Activity Relationships and Discovery of (<i>S</i>)‑5‑(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2′,1′:2,3]imidazo[4,5‑<i>h</i>]quin... by Dimitar Gotchev (1893928)

“…Optimization of a novel series of PAPD5/7 inhibitors that decrease HBsAg levels led to the tetracyclic 2-pyridone <b>AB-161</b>, which was similarly potent to <b>AB-452</b> <i>in vitro</i> and <i>in vivo</i> but showed dramatically higher rodent liver-to-plasma ratios. …”

Treatment of CHIKV-infected mice with PPS improves grip strength and hind-foot swelling. by Penny A. Rudd (10298691)

Distribution of miRs with a greater than two fold-change. by Stephanie L. Samani (17896610)

qqplots of the variables used to create virtual patient dataset. by Yasunori Aoki (339027)

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Fig 9 - by Yasunori Aoki (339027)

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Distribution of baseline patient characteristics in SAVOR-TIMI 53 trial-based dataset used for the clustering and stratified by the resulting clusters. by Yasunori Aoki (339027)

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Patient disposition flow diagram for the dataset for our secondary analysis. by Yasunori Aoki (339027)

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Sankey flow diagram showing the change in distribution comparing when the patients are subtyped according to Ahlqvist et al.’s original methodology (k-means clustering with HbA1c,... by Yasunori Aoki (339027)

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Fig 7 - by Yasunori Aoki (339027)

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Plots of within sum of suqares and Silhouette width both for SAVOR-TIMI 53 trial dataset and virtual patient dataset. by Yasunori Aoki (339027)

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Distribution of the clustering-based diabetes subtypes stratified by the region and race. by Yasunori Aoki (339027)

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Rapamycin treatment decreases α-SMA and Ki67 expression in livers of BDL-Ra rats. by Weijie Wang (247184)

Model example of exponential decay of temporal masking thresholds (normalized to amplitude of 1) at two different temporal masking half-lifes <i>T</i>_<i>½</i> (0.5 ms in... by Eugen Kludt (9962590)

“…At this stimulation rate, <i>T</i>_<i>½</i> of 0.5 ms or 1.1 ms leads to a decrease of the temporal masking threshold by 50% or 20% in the following frame, respectively.…”

Schematic model for the role of JMJD2D in protecting colonic epithelial cells from <i>C</i>. <i>rodentium</i> infection. by Yong Zhang (5893)

Subjects: “…histone demethylase jmjd2d…”

For most sites, observed abundance decreases with size class. by Sarah L. Becker (6631253)

EphA7-FL and EphA7-T1 isoforms have distinct and dynamic expression patterns during cortical development. by Carrie E. Leonard (9732664)

“…D. Quantification of mRNA puncta revealed that the average number of EphA7-FL puncta per cell (blue bars) decreased from DIV7 to DIV21, while the average number of EphA7-T1 puncta (red bars) increased over time in culture. …”

Serum concentrations of semaphorins in patients with chronic hepatitis C (CHC) and healthy controls. by Neven Papic (407314)

“…Serum concentration of SEMA5A decreases with fibrosis progression (<b>B</b>), while serum concentrations of SEMA3C (<b>C</b>) and SEMA6D (<b>D</b>) increase with fibrosis stage. …”

Molecular modeling of BPP-BrachyNH₂ and human ACE and <i>in silico</i> docking studies. by Daniel Dias Rufino Arcanjo (536744)

Effects of supplemental light on tomato rapid chlorophyll fluorescence induction kinetic curves. by Xiaoling Yang (27940)

SOX2-KO decreases HCMV gene transcription. by Le Wen (14587872)