Structure–Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of <i>N</i>‑Acylphosphatidylethanolamine Phospholipase D by Elliot D. Mock (9930184)

“…Previously, we reported <i>N</i>-(cyclopropylmethyl)-6-((<i>S</i>)-3-hydroxypyrrolidin-1-yl)-2-((<i>S</i>)-3-phenylpiperidin-1-yl)­pyrimidine-4-carboxamide (<b>1</b>, <b>LEI-401</b>) as the first potent and selective NAPE-PLD inhibitor that decreased NAEs in the brains of freely moving mice and modulated emotional behavior [Mock Nat Chem. …”

Polymer Coatings in 3D-Printed Fluidic Device Channels for Improved Cellular Adherence Prior to Electrical Lysis by Bethany C. Gross (498246)

“…Cell viability was maintained on the device over a 5 day period (98% viable), though cell coverage decreased after day 4 with static media delivery. Optimal lysis potentials were obtained for the two fabricated device geometries, and selective cell clearance was achieved with cell lysis efficiencies of 94 and 96%. …”

S1 Raw data - by Dao-Cheng Zhou (20314697)

“…We aimed to explore these associations in a national prospective cohort study from NHANES 2005–2018.…”

<b>Artificial cilia for </b><b>360° </b><b>direction-sensitive acoustic</b><b> sensing</b><b> through additive micromanufacturing</b> by Yikang Li (19213120)

“…In this paper, we have prepared a series of artificial cilia <a href="" target="_blank">using </a><a href="" target="_blank">additive micro-manufacturing</a> <a href="" target="_blank">technologies</a> for direction-sensitive acoustic sensing, including <a href="" target="_blank">electrospray and three-dimensional </a><a href="" target="_blank">(3D) micro-direct ink writing</a>. The response of the artificial cilia at resonance is significantly enhanced, while the resonance frequencies decrease with increasing length. …”

eIF5a interacts with Mfn1 and preserves mitochondrial integrity. by Dong Ma (584680)

Stress responsive pathways in <i>clk-1</i> worms are upregulated during larval development and decline with age. by Claire E. Schaar (691681)

“…The upregulation of the oxidative stress response decreases with age. <b>B</b>. The increase in mitoUPR in <i>clk-1</i> worms continues to increase until day 3 of adulthood and then decreases with age. …”

Neutralization fingerprinting of nAbs on a neutralization sensitive Env mutant panel (SENSE-19). by Caio Foulkes (20592250)

GCN2 is required for TPA-induced lytic EBV reactivation and differentiation in WT EBV-infected NOKs. by Deo R. Singh (4784112)

Conditional doxycycline-dependent Pgp-EGFP-expressing hCMEC/D3-MDR1-EGFP cells. by Andreas Noack (519906)

“…Bands were analysed densitometrically and Pgp signals were normalized on actin (D). (E) Induction of Pgp-EGFP by doxycycline (1 µg/ml) significantly decreases Rho123 accumulation in hCMEC/D3-MDR1-EGFP cells confirming that Pgp-EGFP fusion protein is functional. …”

Segment structure prediction and binding site identification for DDLB and CAT-III. by Yang Jiang (46459)

Distention scores. by Akitoshi Inoue (4752867)

Representative absorbance spectra of AMB-PEG 2 and unconjugated AMB formulations prepared in buffers with varying hydrophobicity. by Tessa Rui Min Tan (110571)

Non-native entanglement was formed due to loss of the native entanglement. by Yang Jiang (46459)

Exercise as an Intervention to Reduce Study-Related Fatigue among University Students: A Two-Arm Parallel Randomized Controlled Trial by Juriena D. de Vries (2586829)

<i>clk-1</i> worms are sensitive to acute exposure to oxidative stress but resistant to chronic exposure. by Claire E. Schaar (691681)

“…Chronic assays of oxidative stress could only be performed with paraquat because the toxicity of juglone is decreased within 8 hours. During development, <i>clk-1</i> L2 larvae have decreased survival compared to wild-type worms under conditions of oxidative stress: <b>A</b>. 200 mM paraquat or <b>B</b>. 180 μM juglone. …”

Histological analysis of the effects of dietary chitosan on the kidneys (A and B) and liver (C and D) of <i>B</i>. <i>gonionotus</i>. by Mohammad Abdus Salam (11726108)

Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer’s Agents: Synthesis and Biological Evaluation by Mahesh Shidore (2827802)

“…Furthermore, compound <b>44</b> demonstrated in vivo neuroprotection by decreasing Aβ_1–42-induced toxicity by attenuating abnormal levels of Aβ_1–42, <i>p</i>-Tau, cleaved caspase-3, and cleaved PARP proteins. …”

Supplementary Material for: Topo-Proteomic in situ Analysis of Psoriatic Plaque under Efalizumab Treatment by Bonnekoh B. (4106116)

“…At the ‘EfaBS-centered, double colocation level’ a corresponding decrease was observed for CD2, CD3, CD4, CD8, CD11a, CD13, CD26, CD44, CD45, CD45R0, CD54, CD62L, HLA-DR, and TIA-1. …”

Ligand destabilizing native closed loop rescues misfolded CAT-III. by Yang Jiang (46459)

Non-covalent lasso entanglements in native and misfolded proteins. by Yang Jiang (46459)