Fig 5 - by Mykola Pinkevych (125551)

H2Av regulates Relish SUMOylation by interacting with Su(var)2-10. by Ruijuan Tang (11250680)

“…(C) Knockdown of H2Av and Su(var)2-10 separately or together decreases the amount of SUMOylated Relish (Rel-Smt3). …”

Secondary attack rates among 1407 close contacts based on case-patient^a characteristics, their own characteristics, and exposure setting. by Joseph Walker (4341838)

Hypothetical model for the regulation of ovule development by RNA processing. by Encarnación Rodríguez-Cazorla (689653)

Image_2_HIF2 Regulates Intestinal Wnt5a Expression.tiff by Carolina J. García García (11754761)

Table_2_HIF2 Regulates Intestinal Wnt5a Expression.xlsx by Carolina J. García García (11754761)

A deficiency of TLR9 decreases chronic stress-induced changes of pro-inflammatory cytokine levels by macrophages TLR9 knockout mice or wild type BALB/c mice aged 6 to 8 weeks were... by Yanxiao Xiang (468904)

MtDNA replacement in human oocytes with MRR-SCCT procedure. by Xiaoyu Liao (8161995)

Irradiating the lungs of young adult female FVB/N mice with either a single 12 Gy dose or fractionated 24 or 30 Gy doses of ¹³⁷Cs γ-rays leads to decreased levels of E-c... by Celine Almeida (289132)

“…<b>B, D</b>: After a fractionated 24 Gy dose, there is a slight increase in E-cadherin at 1 month postirradiation (PI) followed by a progressive decrease up to 5 months PI. …”

Quantification of GFP::2xFLAG::SEM-2 expression during M lineage development. by Marissa Baccas (20592105)

“…There is then a gradual decrease in the level of nuclear GFP::2xFLAG::SEM-2 signal in the SM descendants (D). …”

Whole-Body Prepulse Inhibition Protocol to Test Sensorymotor Gating Mechanisms in Monkeys by Patricia G. Saletti (619351)

“…<div><p>Prepulse inhibition (PPI) is the decrease of startle reflex amplitude when a slight stimulus is previously generated. …”

Mendelian randomization results with COVID-19. by Alish B. Palmos (5857379)

Expression of RBM-26 is disrupted by P80L and L13V missense mutations. by Tamjid A. Chowdhury (14149846)

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Bronchoscopic capture of complications with depiction of the midpoint of the anterior-posterior depth of the trachea. by Caterina Zagona-Prizio (14833699)

ISP2 and ISP3 define two additional novel sub-compartments of the IMC. by Josh R. Beck (242399)

“…Red: 7E8 antibody detected by Alexa488-anti-mouse IgG (pseudo-colored red). Green: mRFP-TgCentrin2 (pseudo-colored green). <b>D.</b> The base of the ISP2 compartment terminates in a jagged edge (arrows). …”

Expression of CRYAB in normal and tumor tissue samples across different cancer types. by Rasool Saghaleyni (10526301)