Morpholino-mediated knockdown of <i>lin-28a</i> and <i>lin-28b</i> affects early development. by Yasuo Ouchi (54268)

“…C. D. The efficacy of MO was validated by RT-PCR using primers as indicated in A, B. …”

DataSheet1_N and C Isotope Variations Along an Extreme Eutrophication and Salinity Gradient in the Coorong Lagoon, South Australia.pdf by Stacey C. Priestley (8820455)

Expression of miRNAs and downstream heterochronic genes in <i>lin-28a</i> and <i>lin-28b</i> morphant embryos. by Yasuo Ouchi (54268)

“…<i>lin-28a</i> MO, control MO vs. <i>lin-28b</i> MO, two-tailed test, n = 4, mean ± SEM). D. Semiquantitative RT-PCR analysis of <i>lin-41</i> gene expression in control MO-, lin-28a MO- and lin-28b MO-injected embryos. …”

Figure S1 from PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer by Li-Li Long (14963775)

“…(c) The proportion of each immune cell type in K vs KL. (d) UMAP of sub-clustered cells from lung tumor samples of KP and KPL mice, colored by their 10 major cell types. …”

METTL3 and ALKBH5 oppositely regulate m⁶A modification of <i>TFEB</i> mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes by Huiwen Song (755791)

“…Mechanistically, METTL3 methylates <i>TFEB</i>, a master regulator of lysosomal biogenesis and autophagy genes, at two m⁶A residues in the 3ʹ-UTR, which promotes the association of the RNA-binding protein HNRNPD with <i>TFEB</i> pre-mRNA and subsequently decreases the expression levels of TFEB. …”

MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma by Livia Garzia (266719)

Assessment of weight gain, growth, stunting, pancreas weight and liver weight in C57BL/6 mice fed a low protein diet (LPD, malnutrition diet) or isocaloric normal protein diet (NPD... by Prasad S. Dalvi (405608)

“…Weight of NPD-fed mice was significantly higher than the LPD-fed mice starting at week 1 through week 13 (All data are presented as means ± SD, n ≥ 4 mice per group; two-way ANOVA; interaction *<i>P</i> < 0.05, Tukey’s <i>post hoc</i> test). …”

Enrichment of Treg cells at the disease site of visceral leishmaniasis (VL) patients: by Ambak K. Rai (185132)

“…However, the frequency of Teff cells at disease site (BMMNCs) is decreased as compared to peripheral compartment (PBMCs) (Mean±SEM, <i>p = 0.023, paired t test</i>). ii) FACS plot shows <i>in vivo</i> proliferating (Ki67⁺; an intra nuclear cells proliferating antigen) CD4⁺FoxP3⁻ (Teff) cells in blood and BM of freshly diagnosed VL patients. iii) Significant reduction in the proliferating Teff cells obtained from the disease site of VL patients was observed (<i>n = 3</i>; Mean±SD, <i>p = 0.049, unpaired t test</i>).…”

EHBP-1 is required for the endosomal localization of SID-3. by Jinghu Gao (8816759)

“…(<b>C</b>) Co-immunoprecipitation experiments showing the interaction between SID-3 and EHBP-1. (<b>D</b>) Western blot showing GST pulldown with <i>in vitro</i> translated HA-tagged proteins. …”

CenRICH is suitable for long read sequencing and DNA methylation analysis. by Riccardo Gamba (3458696)

“…WT and KO indicate the genotype of the two HCT116: wild-type or DNMT1 and DNMT3B knock-out, respectively. …”

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults by Nowell H, Phelps

Get full text
Get full text
Get full text