Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects by Alsaad A.M.

“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Theoretical insight into effect of cation–anion pairs on CO2 reduction on bismuth electrocatalysts by Sun Hee, Yoon

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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…Our predictions revealed that E17K, R67W, V164G, E319G, R391G, D32Y, L52H, L52R, and W80R were the most pathogenic mutations. …”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events by Raj, K. Diraviya

“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. by Seidel, Monika

“…The negatively-charged side chains of two aspartate residues (D179 and D180) within the β8-β9 loop are crucial for the N-terminal inter-subunit interaction. …”
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The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection by Anwardeen, Najeha R.

“…Furthermore, data indicated a decrease in sarcosine synthesis from glycine and choline and increase in spermidine synthesis in the BCG vaccinated cohort in T2D and non-T2D groups, respectively. …”
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Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population by Al AdAwi R.M.

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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria by Al-Sadeq, Duaa W.

“…Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). …”
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Impacts of CO2-induced seawater acidification on coastal Mediterranean bivalves and interactions with other climatic stressors by Range, P.

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Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells by Abdulrahman, Nabeel

“…The combination of cisplatin and BI-D1870 also resulted in the inhibition of LC3 II to LC3 I expression when compared to BI-D1870. …”
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS by Hourani, Shireen Bayan

“…The autophagy p62 gene was 61% upregulated, whereas the ATG and LC3-activated cells were lower by 33% at the protein level and 78.3% by flowcytometry, respectively. Nonetheless, CYP3A4, and CYP2D6 were lower in CSCs by 75%, 23%, 43%, 23.8%, and 17%, respectively. …”
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Sliding mode control based dtc of sensorless parallel-connected two five-phase pmsm drive system by Kamel T.

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Biochar of spent coffee grounds as per se and impregnated with tio2: Promising waste-derived adsorbents for balofloxacin by El-Azazy, Marwa

“…Surface morphology, functional moieties, and thermal stabilities of both adsorbents were scrutinized using SEM, EDS, TEM, BET, FTIR, Raman, and TG/dT analyses. BET analysis indicated that the impregnation with TiO2 has increased the surface area (50.54 m2 /g) and decreased the pore size and volume. …”
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Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H2S: DFT study by Salih, Ehab

“…Moreover, the adsorption distance (D) between H2S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes by Abushanab, Dina

“…However, implementing interventions to decrease the T2D incidence, lower SBP, reduce the number of smokers, and improve the total cholesterol could yield gains of 200,408, 198,173, 194,725, and 113,462 PALYs, respectively. …”
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Improving Concrete Durability by Using Optimized Aggregate Gradation and Reducing Cement Content by Chung, Hung-Wen

“…The main findings from this study are as follows: (1) The cementitious content of typical Florida pavement and structural concrete can be reduced by as much as 10 to 15% without loss in workability of the fresh concrete, and without decreasing the strength and durability of the hardened concrete. (2) Portlandlimestone cement (Type IL) can be used as a substitute for ordinary Portland cement (Type I/II). (3) The OAG technique can be used to efficiently reduce the cementitious content of the concrete mixes and to improve their performance."…”
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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions by Salih, Isam M.

“…The overall rate law is represented by Eq. (2) where [CuIL]t and K 1 represent the total copper(II) complex concentration and the pre- equilibrium formation constant, respectively. d [CuL+]/dt = {(ko+k₁ [H+]) [SBr] [CuL]}/(1 + K₁ [SBr])…”
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway by Kuttikrishnan, Shilpa

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Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells by Mannino, Federica

“…These effects were counteracted by AM630 co-incubation, thus confirming that BCP’s mechanism of action is mainly related to CB2R modulation. A decrease in β-catenin regulated the impaired cell cycle and especially promoted cyclin D1 and CDK 4/6 reduction. …”
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