FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”

Schematic representation of possible mechanism of action of OKN-007 in IC3752 pGBM tumor bearing mice. by Patricia Coutinho de Souza (780490)

“…By removing 6-O-sulfates on HS chains and mobilizing protein ligands from HSPG sequestration in the extracellular environment (3), the SULF-2 can increase the solubility of a variety of growth factors (e.g. PDGF) (4) thus increasing the activation of PDGFR-α and downstream signaling pathways in tumor cells (5) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134276#pone.0134276.ref098" target="_blank">98</a>]. …”

Effect of OKN-007 on the immunoexpression of decorin in IC3752 pGBM tumor bearing mice. by Patricia Coutinho de Souza (780490)

Effect of OKN-007 on diffusion measured as ADC values in IC3752 pGBM tumor bearing mice. by Patricia Coutinho de Souza (780490)

Effect of OKN-007 on perfusion rates measured as rCBF in IC3752 pGBM tumor bearing mice. by Patricia Coutinho de Souza (780490)

Brain metabolite ratios in normal and untreated vs. OKN-007 treated IC3752 pGBM tumor bearing mice. by Patricia Coutinho de Souza (780490)

Effect of OKN-007 on the immunoexpression of PDGFR-α in IC3752 pGBM tumor bearing mice. by Patricia Coutinho de Souza (780490)

Beta-catenin signaling is decreased in intermediate progenitor cells. by Christopher A. Mutch (243132)

“…<p>(<b>A</b>) Cortex from E14.5 Axin2-d2EGFP transgenic mice stained for GFP (green), Tbr2 (red), and DNA (blue). …”

VOC Alpha spike protein shows decreased proteolytic processing. by Daniela Niemeyer (199082)

CX treatment leads to decreased perfusion and increased leakage after VEGF-A induced angiogenesis. by Mattias Kalén (224600)

In the absence of chloride, two-fold decrease in [Na⁺]_e shifted GLT-1a E_rev by −28 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…<b>(C)</b> I-V curves of DHK sensitive currents obtained form <b>(B)</b> as a result of subtractions of averages of 2 I-V curves in presence of DHK from averages of 4 I-V curves in the absence of DHK at corresponding [Glu^-]_e and [Na⁺]_e. …”

Decrease of bnAb activity during cell-cell transmission is variable and strain-dependent. by Lucia Reh (546554)

Genes showing upregulated (>2-fold increase) or downregulated (0.5-fold decrease) mRNA expression by 48-hr methylglyoxal treatment. by Kiyoshi Mori (289003)

CpG/c stimulated CLL B cells exhibit decreased survival and decreased activation of the Wnt pathway. by Albert Gutierrez Jr. (342562)

PD 98059 decreases the phosphorylation of ERK in HSVEC, but does not restore ATP-induced decrease in endothelial function in RA. by Padmini Komalavilas (402160)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

Muscle-specific knockdown of <i>nSMase</i> decreases a subset of ceramide species that are decreased in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)

Increased accumulation of mutant huntingtin aggregates and decreased mobility of autophagosomes in the axon of AP-4 ε KO hippocampal neurons. by Raffaella De Pace (5147120)

TG6-44 treatment leads to a decrease in NP-positive cells and altered expression patterns of NP in A/X31 infected THP-1 cells. by Juan A. De La Cruz (11154187)