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19801
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19802
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19803
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19804
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19805
In <i>Drosophila</i> DSK and TO inhibits Gr64f gene transcription and optogenetic activation of Dsk-GAL4 neurons decreases the sensitivity of gustatory neurons in starved flies.
Published 2021“…Depletion of <i>Dsk</i> in all cells (<i>Actin5C-GAL4</i>) decreased <i>to</i> transcripts in flies. …”
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19806
Data_Sheet_1_Five-year measurement data along a 1200 m elevational gradient reveals that global warming increases soil respiration.PDF
Published 2023“…To clarify the effects of soil temperature and volumetric soil water content on soil respiration rates (R<sub>S</sub>), we examined seasonal changes in R<sub>S</sub> at five elevations of 1600–2800 m in subalpine coniferous forests in Japan for 5 years. …”
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19807
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19808
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19809
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19810
Decreases in white matter integrity in t(1;11) translocation carriers (n = 7) versus non-carriers (n = 13) and in patients (n = 34) versus controls (n = 33).
Published 2015“…To aid visualization the results (pfwe < 0.05) are thickened using the “tbss-fill” command. Statistics for FA decreases in the patient group versus controls for these peaks; cluster 1: p = 0.023 at [-3, 28, 6; left genu of corpus callosum], cluster 2: p = 0.032 at [29, 26, 15; right fronto-occipital fasciculus], cluster 3: p = 0.012 at [11, 26, 14; right genu of corpus callosum], cluster 4: p = 0.033 at [20, 25, 0; right acoustic radiation], and cluster 5: p = 0.031 at [28, -24, -8; right fornix] i.e. for clusters 1–5 respectively, see, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0130900#pone.0130900.t002" target="_blank">Table 2</a>).…”
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19811
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19812
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19813
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19814
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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19815
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19816
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19817
Influence of chemical components of PVAC during storage of RBC.
Published 2019“…In <b>(b)</b> values after 1 month (end of storage) are shown: PVA at 100 μg/mL increased hemolysis while PVAC at 2.5 mg/mL, 500 and, 100 μg/mL decreased the levels of hemolysis compared to the control.…”
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19818
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19819
Hepatic IRE1α/XBP1 pathway of the UPR is decreased in pediatric cholestatic liver disease (pCLD) samples compared to pediatric normal (pNormal) livers.
Published 2022“…<p>A) Hepatic gene expression of IRE1α, XBP1s and downstream targets EDEM1 and ERdj4 were measured via qPCR. pCLD livers (n = 10) had decreases in IRE1α, XBP1, EDEM1 and ERdj4 expression compared to pNormal livers (n = 9). …”
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19820
DataSheet_5_Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients.xlsx
Published 2021“…Overall survival was 94% with no severe (grade III-IV) graft-vs-host disease and a 22% rejection rate (graft failure). Hematological parameters, reticulocyte counts, and levels of lactate dehydrogenase (LDH), endothelin-1 and VCAM-1 normalized in SCD patients post-HSCT. …”