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point decrease » point increase (Expand Search)
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2 de » 2 d (Expand Search), _ de (Expand Search), i de (Expand Search)
point decrease » point increase (Expand Search)
de decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
2 de » 2 d (Expand Search), _ de (Expand Search), i de (Expand Search)
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16441
DataSheet1_Enhancing human islet xenotransplant survival and function in diabetic immunocompetent mice through LRH-1/NR5A2 pharmacological activation.pdf
Published 2024“…The discovery that pharmacological activation of the nuclear receptor LRH-1/NR5A2 can reverse hyperglycemia in mouse models of T1D by altering, and not suppressing the autoimmune attack, prompted us to investigate whether LRH-1/NR5A2 activation could improve human islet function/survival after xenotransplantation in immunocompetent mice. …”
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16442
In silico evaluation of the inhibitory potential of nucleocapsid inhibitors of SARS-CoV-2: a binding and energetic perspective
Published 2022“…In addition, the frustration changes due to drug binding brings a decrease in local frustration and this decrease is mainly observed in α-helix, β3, β5, and β6 strands and are important for drug binding. …”
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16445
Two-dimensional bifurcation diagrams of Eq (13) with initial conditions <i>q</i><sub>1</sub>(0) = <i>q</i><sub>2</sub>(0) = 1 in (a) <i>a</i> − <i>b</i>, (b) <i>c</i><sub>1</sub> −...
Published 2023“…<p>The white, yellow, and dark blue regions represent unbounded, chaotic, and fixed point solutions. Each panel is obtained by simulating a grid of 1000 × 1000 parameters that are changing, and the remaining parameters are kept fixed at <i>a</i> = 6, <i>b</i> = 0.5, <i>c</i><sub>1</sub> = 2, <i>c</i><sub>2</sub> = 1, <i>d</i><sub>1</sub> = 0.5, <i>d</i><sub>2</sub> = 1, <i>v</i><sub>1</sub> = 0.1, and <i>v</i><sub>2</sub> = 1. …”
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16449
Effect of Cytosolic pH on Inward Currents Reveals Structural Characteristics of the Proton Transport Cycle in the Influenza A Protein M2 in Cell-Free Membrane Patches of <i>Xenopus...
Published 2014“…<div><p>Transport activity through the mutant D44A of the M2 proton channel from influenza virus A was measured in excised inside-out macro-patches of <i>Xenopus laevis</i> oocytes at cytosolic pH values of 5.5, 7.5 and 8.2. …”
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16451
Representative activity cliffs for the proprietary hERG blocker series 1 (see text) comprised of R1 (corresponding to BP) and R2/R3 (corresponding to BC).
Published 2020“…<p>The large decrease in percent inhibition @ 1 μM for structure 3 compared with structures 1 and 2 is putatively attributable to the greater re-solvation cost of Cl versus F, together with increased polarity and solubility/de-solvation cost of the ortho- versus meta-pyridyl nitrogen, (consistent with the lack of hERG-contributed H-bond replacements for the water solvating this moiety in the unbound state).…”
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16452
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16453
DataSheet_1_Acute infection with Brachyspira hyodysenteriae affects mucin expression, glycosylation, and fecal MUC5AC.pdf
Published 2023“…</p>Results<p>Colonic mucin glycosylation during SD has an overall increase in fucose, a spatially different distribution of GlcNAc with more expression within the crypt lumens of the upper colonic mucosa, and decreased expression or a decreased trend of sialic acids in α-2,6 or α-2,3 linkages, and NeuGc compared to the controls. …”
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16454
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16455
Lateral ventricular wall whole mount immunofluorescence from brains of 2f1 <i>Lrig1</i><sup><em>T2A-iCreERT2/+</em></sup><i>; Rosa26</i><sup><em>Ai14/+</em></sup> mice at 7 days, 1...
Published 2025“…<p dir="ltr">An experiment in Nam and Capecchi, 2020 performed with the <a href="https://doi.org/10.6084/m9.figshare.18092849.v84" rel="noreferrer" target="_blank">line 1c2 mice</a> was repeated with the <a href="https://doi.org/10.6084/m9.figshare.12401006.v129" rel="noreferrer" target="_blank">line 2f1 mice</a> to ensure that the line 2f1 behaves the same as the line 1c2. …”
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16459
Determinants of dietary diversity of pregnant women in the Southern Province of Rwanda.
Published 2024Subjects: -
16460