Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes by Shiliang Li (298790)

“…The long-term antidiabetic efficacies of <b>5</b> (10 mg/kg, qw) were better than those of the once-weekly trelagliptin and omarigliptin, especially in decreasing the hemoglobin A1c level.…”

Gene Ontology network analysis of differentially-enriched Vpu-proximal protein subsets. by Charlotte A. Stoneham (10819125)

Uncertainty analyses of unadjusted data from Scenarios 1–3: each dot represents one simulation. by Jie Lou (535356)

IC₅₀ values of REJO SP mutants vs. WT by MAbs targeting V2i, V3, V2q, and the CD4bs and by CD-IgG2. by Chitra Upadhyay (817121)

Longitudinal associations between baseline CVR and 2 years changes in BDI-II score in participants with a BDI-II score <18 in the PREDIMED-PLUS trial at baseline. by Sandra Martín-Peláez (11353470)

Association between cardiovascular risk and a) depressive status (BDI-II ≥18) and b) BDI-II score, in the PREDIMED-PLUS trial, stratified by CVR factors, at baseline. by Sandra Martín-Peláez (11353470)

Table_5_New evidence for the effect of type 2 diabetes and glycemic traits on testosterone levels: a two-sample Mendelian randomization study.xlsx by Chengyang Jiang (1540369)

Scheme [37] and photo of a device for extracting tritium from plants’ tissue free water (1 –organic glass container; 2 –lid; 3 –cone-shaped refrigerator; 4 –receiving tank holder;... by Yelena Polivkina (14341291)

Inflammatory phenotype of APN-/- mice from a second strain. by Sri Harshini Goli (20889928)

<i>Prss21</i>^<i>-/-</i> mice display a hemorrhagic phenotype during vascularization of the corpus luteum. by Raymond J. Peroutka (8946971)

PM26, a specific antagonist of DC-SIGN, can inhibit DC-SIGN/S protein interaction and trans-infection of VSV/SARS-CoV-2. by Michel Thépaut (7462022)

“…The IC₅₀ value for PM26 was estimated using GraphPad Prism v8 with a 95% confidence interval and settings for normalize dose-response curves (IC₅₀ = 94 nM, 95%CI = 35 nM– 249 nM).…”

Image_5_A Fenton-like cation can improve arsenic trioxide treatment of sclerodermatous chronic Graft-versus-Host Disease in mice.tif by Charlotte Chêne (11221620)

“…In vivo, in a cGvHD mouse model, daily injections of ATO 2.5 µg/g + CuCl₂ 0.5 µg/g induce a decrease in lymphocyte activation and fibrosis that was equivalent to that induced by ATO 5 µg/g. …”

DataSheet1_High-Temperature Tribological Behavior of Al0.3Cr0.5Fe1.5Mn0.5Ni High-Entropy Alloys With Addition of Titanium and Carbon.PDF by Chun-Hao Peng (11935217)

“…After high-temperature wear testing, the HEAs demonstrated exceptional oxidation resistance and a lower friction coefficient than M2 steel since the dense glazed layer on the surface of the HEAs served as a lubricant to decrease the friction coefficient, and protected the substrate from oxidation.…”

Map of study sites, village locations, and treatment allocation. by Myra Hardy (6871334)

Health outcomes and adherence to a healthy lifestyle after a multimodal intervention in people with multiple sclerosis: Three year follow-up by Claudia H. Marck (693293)

“…Furthermore, participation in a lifestyle intervention is not associated with a decrease in MS medication use.…”

Model performance comparison. by Shayla Naznin (13014015)

“…<div><p>Background</p><p>Under-5 mortality remains a critical social indicator of a country’s development and economic sustainability, particularly in developing nations like Bangladesh. …”

Fig 3 - by George Rucker (17101889)

“…Colors range from blue to white to red (with white representing no change in RMSF, blue representing RMSF decrease, and red representing RMSF increase). The ΔRMSF is in the range from -0.5 (totally blue) to 0.5 (totally red).…”

Supplement figure 3 by Anthony Tam (9465092)

DataSheet_1_Methylation of SPRED1: A New Target in Acute Myeloid Leukemia.docx by Nan Su (323312)

“…To determine the possible mechanism of SPRED1 methylation in AML, we performed in vitro experiments using THP-1 cells, as the latter showed the highest methylation level (determined by utilizing bisulfite modification) among the three AML cell lines we tested. When treated with 5-AZA and lentivirus transfection, upregulated SPRED1 expression, decreased cell proliferation, increased cell differentiation and apoptosis, and inactivated phosphorylated extracellular signal-regulated kinase (p-ERK) were detected in THP-1 cells. …”

(a) Concentration of total soluble solids (TSS; °Brix), (b) acid (%), and (c) °Brix:acid ratio of Redlands Joy strawberry fruit arising from unassisted self-pollination (Autogamy)... by Cao Dinh Dung (11401910)