Data Sheet 1_Polarization of Vδ2 T cells to a Th2-like phenotype promotes plasmablast differentiation and possesses pro-fibrotic properties in IgG4-related disease.docx by Jieqiong Li (327149)

“…</p>Results<p>Patients with IgG4-RD exhibited decreased peripheral Vδ2 T cells displaying a Th2-like phenotype characterized by elevated Th2 cytokine production and activated IL-21—STAT3—Blimp-1—GATA3 pathway. …”

Tamoxifen decreases fasting glucose and improves glucose tolerance in C57Bl/6J mice; Tamoxifen significantly reduces β-cell proliferation in C57Bl/6J mice. by Surl-Hee Ahn (7354373)

Data_Sheet_1_RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2.PDF by Farhad Vesuna (354371)

“…However, evolving variants of the virus appear to be more transmissive and vaccine efficacy toward them is waning. As a result, SARS-CoV-2 will continue to have a deadly impact on public health into the foreseeable future. …”

Study of myelin structure changes during the nerve fibers demyelination - Fig 6 by Natalia N. Rodionova (4452793)

Mitotic catastrophe is dependent on CRM-1 dysregulation. by Zachary J. Hough (20840430)

Fig 2 - by Carla Schenker (6661655)

ROS reduces the expression of Akt3, WDR12 and Aurora B leading to micronuclei. by Zachary J. Hough (20840430)

Image_1_Case Report: Difficulties in the Treatment of a 12-Year-Old Patient With Homozygous Familial Hypercholesterolemia, Compound Heterozygous Form − 5 Years Follow-Up.JPEG by Lyudmila Vladimirova-Kitova (11537353)

“…Initial treatment, based on European recommendations, included Atorvastatin 20 mg and Ezetimibe 10 mg and led to a decrease in LDL-C by 46% for 5 months; however, the patient developed severe statin intolerance. …”

Supplemental data 3. by Zachary J. Hough (20840430)

“…Akt3 null hearts at midgestation (E14.5), a stage in which proliferation is occurring, have decreased Aurora B expression, increased CRM-1 expression, decreased proliferation, and increased apoptosis. …”

V1 developmental data appear to challenge the canonical sparse coding models. by Joel Zylberberg (340947)

“…<p>Multi-unit activity in primary visual cortex (V1) of awake young ferrets watching natural movies shows decreasing sparseness over time. …”

Pharmacological induction of mitochondrial dysfunction results in micronuclei and nuclear blebbing. by Zachary J. Hough (20840430)

Open data. by Larissa Brazolotto Ferreira (17671168)

“…</p><p>Results</p><p>There was a significant decrease in BMD in the lumbar spine (1.107 ± 0.109 and 1.075 ± 0.112 g/cm²; <i><i>p</i></i> < 0.001), total body (1.135 ± 0.086 and 1.119 ± 0.085 g/cm²; <i><i>p</i></i> < 0.001), and total proximal femur over the six months of EBF compared to the values obtained from the same EBF group at 15 days postpartum (mean percentage decreases in BMD of −3.4 ± 3.7% (<i><i>p</i></i> < 0.001) in lumbar spine, −2.5 ± 3.4% (<i><i>p</i></i> < 0.001) in total proximal femur, and −1.7 ± 1.9% (<i><i>p</i></i> = 0.001) in total body). …”

Spatial variation within and across lakes in chl-a trends (1997–2020). by Benjamin M. Kraemer (7526225)

Unbiased search for lipid droplet-associated lipases involved in HCV assembly. by Gabrielle Vieyres (409404)

“…Arrows pointing upwards, arrows pointing downwards and the equal sign indicate respectively an increased, decreased or unchanged lipid droplet association upon HCV infection [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008554#ppat.1008554.ref039" target="_blank">39</a>]. …”

Future ozone-related acute excess mortality under climate and population change scenarios in China: A modeling study by Kai Chen (129938)

“…Using historical ozone monitoring data, we performed bias correction and spatially downscaled future ozone projections at a coarse spatial resolution (2.0° × 2.5°) for the period April 27, 2053, to October 31, 2055 (2053–2055), from a global chemistry–climate model to a fine spatial resolution (0.25° × 0.25°) under 2 Intergovernmental Panel on Climate Change Representative Concentration Pathways (RCPs): RCP4.5, a moderate global warming and emission scenario where global warming is between 1.5°C and 2.0°C, and RCP8.5, a high global warming and emission scenario where global warming exceeds 2.0°C. …”

Heterogeneity analysis. by Ying Zhao (16546)

“…Heterogeneity tests, horizontal pleiotropy tests, and the leave-one-out method were applied to evaluated the robustness of the MR analysis results. A total of 117 SNPs were employed as instrumental variables (<i>P</i> < 5 × 10⁻⁸). …”

Reverse MR analysis data. by Ying Zhao (16546)

“…Heterogeneity tests, horizontal pleiotropy tests, and the leave-one-out method were applied to evaluated the robustness of the MR analysis results. A total of 117 SNPs were employed as instrumental variables (<i>P</i> < 5 × 10⁻⁸). …”

SNP dressing by screening. by Ying Zhao (16546)

“…Heterogeneity tests, horizontal pleiotropy tests, and the leave-one-out method were applied to evaluated the robustness of the MR analysis results. A total of 117 SNPs were employed as instrumental variables (<i>P</i> < 5 × 10⁻⁸). …”

Image_1_Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Pr... by Celia Di Munno (10230458)

Image_6_A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins.TIF by Sarra El-Soussi (11228799)

“…The protein expression of tumorigenic NMYC, Sox-2, Oct-4, FABP5, and HMGA1 significantly decreased 48 h post-drug treatment, whereas cleaved PARP1/caspase-3 and γH2AX increased 72 h post-drug treatment, compared with vehicle-treated cells in the MYCN-amplified IMR-32 cell line. …”