Tumor inhibition in mouse model, and effects on EGFR expression and Akt phosphorylation. by Satoshi Inoue (221875)

“…<p>(5a) Tumor growth inhibition in mice. MDA-MB-468 subcutaneous breast tumors treated systemically with P/AON/2C5, or P/AON/2C5/TfR were significantly inhibited compared with PBS (control), P(polymer only), or P/2C5 (without anti-tumor component) (P<0.03). …”

IGF-1-induced enhancement of <i>PRNP</i> expression depends on the activation of PI3K-Akt signaling pathway. by Ting Liu (45625)

“…The LY294002-treated cells (lanes 2 and 6) showed a remarkable decrease in the PrP^C protein level compared with the DMSO-treated group (lanes 1 and 5). …”

Loss of <i>Hes1</i> impairs neural crest development. by Francesca Rochais (371680)

“…<p>(A) In situ hybridization at E9.5 showing decreased <i>Crabp1</i> transcript accumulation in the caudal pharyngeal region of <i>Hes1</i>^−/− compared to <i>Hes1</i>^+/+ embryos (arrowheads). …”

RMS-error. by Roger Abächerli (812650)

“…<p>The mean RMS-error decreases for increasing DC-gain, M, here shown on a log-log plot. …”

Reduced Susceptibility of DNA Methyltransferase 1 Hypomorphic (Dnmt1^N/+) Mice to Hepatic Steatosis upon Feeding Liquid Alcohol Diet by Huban Kutay (144581)

“…<div><h3>Background</h3><p>Methylation at C-5 (5-mdC) of CpG base pairs, the most abundant epigenetic modification of DNA, is catalyzed by 3 essential DNA methyltransferases (Dnmt1, Dnmt3a and Dnmt3b). …”

Measures of emphysema. by Steven Zhou (440982)

“…<p>1A: Mean airspace size is increased by a similar amount in young and old animals. 1B. …”

Serological response to rabies virus induced by commercial vaccines in cattle by Mathias Martins (4649428)

“…However, the titers decreased, reaching titers <0.5UI/mL in approximately 70% of animals within the interval before the recommended booster. …”

Table 1_New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis.doc by Alexander Rodero-Romero (20172186)

Model results of the effects of developmental interactions on transient alpha diversity and stationary beta diversity in an environment discretized into 25 patches (see S9 Fig). by Fernando W. Rossine (8599806)

“…In a stochastic environment with mean starvation time = 430 hours (symbol with black boundary in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000642#pbio.3000642.g005" target="_blank">Fig 5E</a>), the mean extinction time decreases (decreased transient alpha diversity), but the variability in the winner across patches increases compared to segregated development (increased stationary beta diversity). …”

Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia by Shao-Qing Kuang (217209)

“…Aberrant methylation of Notch3 and Hes5 in B-ALL was associated with gene silencing and was accompanied by decrease of H3K4 trimethylation and H3K9 acetylation and gain of H3K9 trimethylation and H3K27 trimethylation. 5-aza-2′-deoxycytidine treatment restored Hes5 expression and decreased promoter hypermethylation in most leukemia cell lines and primary B-ALL samples. …”

TNF-Tg male mice have greater tissue area compared to WT litter mates measured via histomorphometry. by Richard D. Bell (4752660)

“…Interestingly, when normalized to total area, there was a significant decrease in the White area at 3, 4, and 5.5 months in TNF-Tg mice compared to WT littermates (<b>K;</b> *p<0.0125, **p<0.01, ***p<0.001, M±SD, n = 4–6).…”

Residual intake and gain for the evaluation of performance, non-carcass components, and carcass characteristics of confined crossbred Texel lambs by Mayara Mitiko Yoshihara Carneiro (5380289)

“…The first phase included 47 lambs with an initial average weight of 29.9±5.5 kg, and the second phase included 30 lambs with initial average weight of 22.4±3.3 kg. …”

Gal-9 attenuates pulmonary emphysema induced by PPE. by Yuko Horio (4243405)

“…PPE- or saline-treated mice were further subdivided and treated subcutaneously with Gal-9 in PBS or PBS alone once a day from one day before PPE instillation to day 5. …”

The effect of neutralizing endogenous TGF-β on RV replication. by Nicole Bedke (137686)

“…<p>PBECs from 8 asthmatic donors or 6 non-asthmatic control subjects were pretreated for 24 h in the presence of a neutralizing anti pan TGF-β antibody or isotype control antibody before infection with RV1B (1000 units/10⁵ cells) for 48 h. …”

Graph to show numbers of cells observed on the articular cartilage surface by Frances MD Henson (78253)

“…At day 11 and day 20 there was a significant decrease in the number of cells on the cartilage surface in the samples cultured in the presence of 100 ng/ml BMP-2 (*) compared to both control and SIL sections.…”

Outcomes of curtailing fishing for penguins by SSMU. by Emily S. Klein (4811307)

“…Points below the dashed 1:1 line indicate a decrease in depletion risk owing to a cessation in fishing. …”

MicroRNA profile of nicotine-treated vs non-treated cells. by Michael Andrew Yu (292167)

“…Genes were excluded based on the criteria of having at least 20% of expression values showing a 1.5 fold increase or decrease relative to the median. …”

Treatment of xenograft tumors by chemotherapy. by Wolfgang Jäger (394799)

“…<p>A. Mice bearing UM-UC13 luc tumors showed a remarkable decrease in tumor volume after systemic therapy with a combination of gemcitabine and cisplatin starting on day #28 after inoculation, compared to PBS control (** = P<0.01). …”

Temporal changes of TH levels in the striatum of PD-induced rats. by Gabriela P. Chaves-Kirsten (468145)

“…<p>TH levels in striatum of rats submitted to unilateral intrastriatal injections of 6-OHDA after 1, 5, 10, 20, and 60 days post-lesion (DPL). (A) Digital images of coronal sections of the dorsolateral striatum shows a decrease in the expression of TH on the 6-OHDA side, with a peak in 10 DPL (B) Digital images of coronal sections of the dorsolateral striatum at 60 DPL; the arrow indicates the site of infusion. …”

Perceived effort for motor control and decision-making - Fig 1 by Ignasi Cos (838096)

“…<p><b>(A)</b> Utility function traces (solid traces) resulting from trading off benefits (black solid trace) minus their associated costs (dashed-dot traces) as a function of movement time (T) for reaching movements of path distance (D) between 5 and 25 cm. …”