Image_2_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Image_4_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Table_2_Glucocorticoid Effects on Tissue Residing Immune Cells in Giant Cell Arteritis: Importance of GM-CSF.DOCX by Annette D. Wagner (6496358)

“…A decrease of CCL19 and CCL21 expression was observed after starting glucocorticoid therapy. …”

Luminex results of cytokines regulated by IL-1Ra. by Connie S. Chamberlain (440242)

“…Blockade of the IL-1 activation resulted in an accumulation of IL-1α (a) and IL-1β (b). By day 11, inhibition of the IL-1R resulted in a down-regulation of IL-1α (a) and tended to decrease IL-1β (b; p = .056). …”

Serum-differentiation leads to enhanced MMP9 expression. by Justin V. Joseph (697904)

“…</b> Western blot showing a decrease in MMP9 expression in differentiated GG16 cells following the administration of CP 471474, a chemical inhibitor of MMP9. …”

Theophylline attenuates bleomycin-induced oxidative stress in rats: The role of IL-6, NF-κB, and antioxidant enzymes by Suat Ekin (6165095)

“…Assigned into 4 groups were 32 Wistar albino rats, comprising the control group (administered 0.9% isotonic saline), BLM group (treated with BLM at a dose of 2.5 mg/kg), BLM+Theo group (treated with Theo at a dose of 75 mg/kg + BLM at a dose of 2.5 mg/kg), and Theo group (treated with Theo at a dose of 75 mg/kg). …”

Changes in economic decisions in an increasingly reward-scarce environment. by Brian M. Sweis (5434976)

“…Transition to the 1–30 s block caused a significant decrease in food intake and reinforcement rate. …”

Presentation_1_Glucocorticoid Effects on Tissue Residing Immune Cells in Giant Cell Arteritis: Importance of GM-CSF.PPT by Annette D. Wagner (6496358)

“…A decrease of CCL19 and CCL21 expression was observed after starting glucocorticoid therapy. …”

Image_3_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Ni-Assisted Transformation of Graphene Flakes to Fullerenes by Irina V. Lebedeva (347621)

“…The Ni clusters are shown to reduce the activation energy for the graphene–fullerene transformation from 4.0 eV to 1.5–1.9 eV, providing the decrease of the minimal temperature at which such a transformation can be observed experimentally from about 1400 K for free graphene flakes to about 700–800 K. …”

Orientation tuning curves of neuron pairs responding to drifting gratings were recorded in area 17 by Narcis Ghisovan (94543)

“…Color code – blue: control, red: adaptation, green: 60 minutes later (error bars denote SEM). (A) Example of an adaptation-induced shift of 18.5° to the right for the cell GM1-x1 and a small shift of 4.5° in the same direction for the other cell GM1-y1. …”

<i>IL23R</i> gene variants modulate intestinal DMBT1 expression. by Julia Diegelmann (107830)

“…<i>P</i> values in column (4) are given for the comparison of the DMBT1 expression of carriers of the <i>IL23R</i> minor allele (homozygous and heterozygous) compared to DMBT1 levels in <i>IL23R</i> wild-type carriers. Column (5) summarizes the data from column (3) and represents the fold increase or decrease in DMBT1 expression in carriers of the <i>IL23R</i> minor allele (homozygous and heterozygous) compared to DMBT1 levels in <i>IL23R</i> wild-type carriers for the respective <i>IL23R</i> SNP. …”

Ni-Assisted Transformation of Graphene Flakes to Fullerenes by Irina V. Lebedeva (347621)

“…The Ni clusters are shown to reduce the activation energy for the graphene–fullerene transformation from 4.0 eV to 1.5–1.9 eV, providing the decrease of the minimal temperature at which such a transformation can be observed experimentally from about 1400 K for free graphene flakes to about 700–800 K. …”

Image_1_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

TIME SERIES TRENDS OF STREAMFLOW AND RAINFALL IN THE SANTO ANTÔNIO RIVER BASIN, BRAZIL by Fernanda L. V. Ferreira (10383961)

Effect of SENP1 over-expression on JNK activation and cell viability after overnight or 3 h stimulation with H₂O₂. by Marco Feligioni (287395)

“…<p><b>A</b>) Representative Western blot showing decrease in P-JNK protein levels in cells overexpressing SENP1 following overnight stimulation with H₂O₂. …”

Loss of Fnip1 synergizes with loss of TSC1 resulting in accelerated PKD and mTOR activation. by Ryan Centini (5390768)

“…(D) Immunoblots of proteins isolated from whole kidney lysates derived from 5 week-old wildtype, <i>Tsc1</i>^<i>-/-</i>, and <i>Tsc1</i>^<i>-/-</i><i>Fnip1</i>^<i>-/-</i> blots showing increased p-Erk, p-S6R, and p-4E-BP in <i>Tsc1</i>^<i>-/-</i> <i>Fnip1</i>^<i>-/-</i> kidney tissue compared to <i>Tsc1</i>^<i>-/-</i> and WT mice indicating hyperactivation of the mTORC1 and Erk pathways. p-AMPK is decreased in double null mice relative to <i>Tsc1</i>^<i>-/-</i> and WT mice, suggesting decreased AMPK activation. …”

MORPHOLOGY AND PRODUCTION OF WEST INDIAN CHERRY IRRIGATED WITH SALINE WATERS UNDER COMBINATIONS OF NITROGEN-POTASSIUM FERTILIZATION by EVANDRO MANOEL DA SILVA (8369322)

“…The experiment was carried out in the CCTA/UFCG, in 60-L lysimeters installed in the field, in a randomized block design and 5 x 4 factorial scheme, referring to five levels of irrigation water salinity (ECw), i.e., 0.3, 1.3, 2.3, 3.3, and 4.3 dS m-1, and four combinations (C) of nitrogen-potassium fertilization, i.e., C1 = 70% N + 50% K2O; C2 = 100% N + 75% K2O; C3 = 130% N + 100% K2O, and C4 = 160% N + 125% K2O of the recommended dose for West Indian cherry, with three replicates and one plant per plot consisting of a lysimeter. …”

Electroretinographic evidence suggesting that the type 2 diabetic retinopathy of the sand rat <i>Psammomys obesus</i> is comparable to that of humans by Ahmed Dellaa (4840146)

“…In photopic conditions, diabetic rats showed a significant decrease in a- and b-wave (30.4%, 43.4%), photopic negative response (55.3%), 30 Hz flicker (63.7%), OP1-OP4(51.6%, 61.8%, 68.3% and 47.5% respectively) and S-cone (34.7%). …”

Image_1_CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1.JPEG by Jiayi Zhou (2228527)

“…Moreover, CD44 knockdown caused a decrease in cell clone formation, migration, and invasion of HOPM and HOPM-Snail cells.…”