Ectopic Expression of the RING Domain of the Arabidopsis PEROXIN2 Protein Partially Suppresses the Phenotype of the Photomorphogenic Mutant <i>De-Etiolated1</i> by Mintu Desai (632853)

“…Although we have not been able to detect this hypothetic peptide <i>in vivo</i>, we show in this study that, when fused with a fluorescent protein and overexpressed, the PEX2 RING domain can localize to the nucleus, where it is able to interact with HY5, and PEX2 RING domain overexpression in <i>det1</i> also partially suppresses the <i>det1</i> phenotype. …”

Decreasing patterns of P_WT scores in 6 conditions with individual values (0.05, 0.1, 0.2, 0.3, 0.4, and 0.5). by In Seok Yang (4261207)

Echocardiographic measurements in WT and AMPKα2-/- mice following transverse aortic constriction. by Anne Garnier (130125)

Subjects:

Proteome analysis of plasma from ATTR individuals. by Gonçalo da Costa (198731)

Variants enriched in an <i>Ae</i>. <i>aegypti</i> cell line <i>(</i>Aag2) have increased fitness in Aag2 cells but decreased fitness in a human cell line (MRC-5). by Chelsea Cereghino (15188341)

The variant mimicking hyperphosphorylation of human 4E-BP does not decrease its association with eIF4E. by Nathalie Oulhen (373674)

Decrease in the number of years of MDA required for 90% onchocerciasis elimination probability in an area with two or three connected villages, by treatment implemented also in the... by Anneke S. de Vos (3202548)

“…Prevalence is among those aged 5+ years. For the three village settings (blue markers), the average prevalence of Villages 2 and 3 is indicated on the x-axis, and on the y-axis the decrease in required duration by additional treatment in both of these villages (alternative comparisons with three villages are shown in Fig L in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0009011#pntd.0009011.s001" target="_blank">S1 Text</a>). …”

Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner by Qian Zhao (217607)

“…The silk ligature was tied around the maxillary second molars for 14 days, during which the CpG+CD40L mixture or PBS was injected into palatal gingiva on days 3, 6, and 9. Results: For both WT and TLR9 KO mice, CpG significantly induced B cell proliferation, increased IL-10 mRNA expression and protein secretion of IL-10 but reduced CD1dhiCD5+ B cells population; local injection of CpG+CD40L mixture significantly decreased alveolar bone loss and the number of TRAP-positive cells adjacent to the alveolar bone surface, and significantly increased the gingival mRNA expression of IL-10 and decreased RANKL and IFN-γ mRNA expression. …”

S C-terminal mutations that decrease ezrin interaction enhance transduction by pseudotyped particles in Vero E6 cells. by Jean Kaoru Millet (117227)

Comparison of WT and mutant SHC014-CoV S ectodomains. by Alexandra L. Tse (20235212)

“…Area under the curve represents protein expression. A835D-containing variants exhibit a large decrease in protein expression relative to the WT and F294L SHC014-CoV spikes. …”

(A) The proportion of fast MyHC myotubes is decreased in Igf-2 deficient mice (maternal disomy Chromosome 7 - MatDi) at E14 by Deborah Merrick (54928)

“…(B) Embryo immunoblotting for Igf-2 demonstrates a stage related increase in Igf-2 protein between E10.5 and E15.5 in WT and absence of Igf-2 in MatDi embryos at E14.5 and E15.5 Tracks 1–4 E10.5, E13.5, E14.5 and E15.5 WT embryos respectively, Track 5 E14.5 MatDi, Track 6 E15.5 MatDi and Track 7 E15.5 WT. …”

Enhanced Nrf2 activity decreases lipid clearance rate and VLDL secretion in Keap1-KD mice. by Jialin Xu (40952)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

HENMT1 loss results in decreased piRNA bulk and the absence of 3’ 2’-O-methylation and stability. by Shu Ly Lim (578590)

The effect of free rNTPs on the processivity of WT and exo^- Pol γ. by Josefin M. E. Forslund (5043218)

Decreased <i>Pax2</i> expression in <i>p53^−/−</i> embryonic kidneys. by Zubaida Saifudeen (135684)

“…<b>B</b>) In situ hybridization. Decreased expression of <i>Pax2</i> mRNA at E12.5. …”

The inflammatory process resulting from TIN is decreased in TLR 2, -4, and MyD88 KO mice. by Matheus Correa-Costa (119464)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…Anti-phospho-cofilin antibody showed that MK-STYX decreased cofilin phosphorylation in non-stimulated cells relative to the MK-STYX shRNA-A. …”

Microbiocidal activity and limited bacteria-cell contact does not provide for decreased phagocytic clearance of non-swimming bacteria. by Rustin R. Lovewell (205423)

Mutations in the QseE N-terminus impairing interaction with QseG concomitantly decrease QseE activity. by Yvonne Göpel (5549291)